Carbary Case Study

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Based on the symptoms the patient is presenting with and the knowledge that he had been gardening before becoming sick, it is likely the patient came into contact with insecticide and is being affected by the active ingredient Carbaryl. Carbaryl is an acetylcholinesterase inhibitor and muscarinic receptor agonist, so it inhibits the enzyme acetylcholinesterase from breaking down the neurotransmitter acetylcholine. This hyper activates the nicotinic and muscarinic synapses and in turn activates the sympathetic and parasympathetic nervous system. The sympathetic nervous system is what caused the initial tachycardia and hypertension. Bradycardia and hypotension along with the other main symptoms are caused by over activation of the muscarinic

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