Cancer Is The Major Cause Of Death From Cancer

Cancer is a general term for a large group of diseases that can affect any part of the body; it is caused by mutations to the original genetic code. Cancer, in its simplest explanation, is the uncontrolled growth of cells within the body resulting in the accumulation of large masses of cells, commonly known as tumours.

One significant Characteristic of cancer is the rapid multiplication of mutated cells that grows beyond their usual limits and result in tumours, some tumour cells also have the ability to break free from their original tumour and invade other parts of the body and spread to other organs, using the circulatory system as a carrier. This process is referred to as metastasis and is the major cause of death from cancer.

According to the WHO an estimated 8.2 million people die each year from cancer and cancer related issues, and this figure is expected to increase by 70% over the next two decade 1. The key focus from the WHO to try and combat this pandemic is to focus on prevention rather that cure, with the elimination/reduction key contributing factors which can lead to cell mutation e.g. tobacco, Alcohol and certain processed food types. However, this is no easy feat and control of these elements does not account for other influencing factor that lead to the growth of the rouge cells that result in cancerous tumours within the body.

The most common types of Cancer in males are Lung, prostate, colorectal, stomach, and liver cancer, while breast, colorectal, lung, uterine cervix, and stomach cancer are the most common among women. It is thought that greater than 30% of cancer deaths could be prevented by making small changes to daily routines and habits. Early detection, accurate diagnosis, and effective treatment, help...

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...optosis.

Satraplatin, like Cisplatin and other analogues, also works by the formation of DNA adducts to inhibit cell replication and lead to Apoptosis. Satraplatin has demonstrated potent antitumor activity in vitro and in vivo against various tumor cell lines, including ovarian, cervical and lungs that are sensitive or resistant to cisplatin (8). Even though Satraplatin is still in the clinical phase and its full efficacy in its specific area of treatment remains to be understood, it has the advantage over cisplatin of a better toxicity profile and oral route of administration.

With the increasing focus from the pharmaceutical industry on trying to uncover the next breakthrough cancer therapy and ever advancing technologies available to support research and development activities, further discoveries within the Cisplatin family still remain to be unearthed.