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Essay of informed consent
Ethics in biomedical research
Ethics in biomedical research
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The Immortal life of Henrietta Lacks highlights how ethically flawed medicine once was and perhaps still is. It tells the devastating story of a woman whose cells were collected and cultured without her consent and its wondrous effect within the medical community as well as the equally distressing effect on her family. Preceding the 50s, scientists, specifically Dr. George Otto Gey have been trying without success to cultivate human cells in laboratories for decades. Henrietta Lacks was an African American tobacco farmer who was diagnosed and eventually succumbed from cervical cancer in 1951. Prior to her treatment, Lacks signed a statement permitting any surgery necessary but Dr. Wharton, before beginning the radium treatment, takes two samples from the unconscious Henrietta without her knowledge; one from her tumor and another from healthy tissue. He then provides Dr. TeLinde with these samples, who in turn delivers them to Dr. Gey. These cancerous, then dubbed, HeLa cells began to grow successfully and Gey began to give samples out to his colleagues, essentially staring a billion dollar industry.
The author, Rebecca Skloot illustrates the ethical dilemmas of informed consent, disclosure, confidentiality, and of what rights people had or have over their organs, tissues, cells etc. The book also focuses on race, being that it was more prevalent at the time.
Disclosure is an essential aspect of a medical professional and his or her patients’ relationships. In the 1950s, the medical client and professional relationship was one of paternalism as opposed to the now fiduciary relationship. Then a paternalistic professional took all of the responsibilities, disclosed what he then thought was necessary, and essentially told the patien...
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... the reason that because of their actions, millions of people were saved. The HeLa cells were a crucial tool in modern medicine as they were vital in developing the polio vaccine, cloning, and gene mapping, as well as studying several viruses. A Utilitarian, being exclusively focused on consequences would view that the ethical breach in regards to Henrietta Lacks as necessary. Ethics of Care however, would view the doctors’ actions as unethical because feminist ethics prioritizes personal relationships and moral responsibility. Ethics of care emphasizes on caring for others but Lacks’ doctors were only thinking of themselves and trying to revolutionize medicine that they horribly mistreated her which was largely due to her race. So, in the perspective of Feminist ethics, the doctors’ exploitation and the overall garnering of HeLa cells was an immense ethical breach.
The book The Immortal Life of Henrietta Lacks by Rebecca Skloot is the result of years of research done by Skloot on an African American woman with cervical cancer named Henrietta Lacks. Cells from Lacks’ tumor are taken and experimented on without her knowledge. These cells, known as HeLa cells, are the first immortal human cells ever grown. The topic of HeLa cells is at the center of abundant controversial debates. Despite the fact that her cells are regarded as, “one of the most important advancements in the last hundred years” (4), little is actually known about the woman behind the cells. Skloot sets out on a mission to change this fact and share the story of the woman from whom the cells originate and her family as they deal with the effects these cells have on them.
Henrietta’s cells were being inaugurated with space travel, infused into rat cells, and even being used to make infertile hens fertile again. However, these are only a few of the many accomplishments that Henrietta’s immortal cells made possible: “The National Cancer Institute was using various cells, including HeLa, to screen more than thirty thousand chemicals and plant extracts, which would yield several of today’s most widely used and effective chemotherapy drugs, including Vincristine and Taxol,”(pg.139). This example of logos from the text again shows just how important these Henrietta’s cells were to the future developments in
In the novel The Immoral Life of Henrietta Lacks by Rebecca Skloot, the author tells the miraculous story of one woman’s amazing contribution to science. Henrietta Lacks unknowingly provides scientists with a biopsy capable of reproducing cells at a tremendusly fast pace. The story of Henrietta Lacks demonstrates how an individual’s rights can be effortlessly breached when it involves medical science and research. Although her cells have contributed to science in many miraculous ways, there is little known about the woman whose body they derived from. Skloot is a very gifted author whose essential writing technique divides the story into three parts so that she, Henrietta
In order to fully understand the significance of the life of Henrietta Lacks, one must first understand the nature of the historical moment in which she lived, and died. Henrietta Lacks was a poor, African American woman born in 1920; Henrietta lived in Clover, Virginia, on a tobacco farm maintained by many generations of relatives. This historical moment can best be understood when evaluated using a structural analysis; a structural analysis is an examination of multiple components which form an organization; structural analyses often focus on the goals and purpose of the organization in question. Henrietta and her family were greatly affected by structural violence, a type of systematic violence exerted via legislation and discrimination. Often following systematic violence is a separate type of violence, known as symbolic violence; this occurs when structural violence is viewed as normal based on media representation or popular
The Immortal Life of Henrietta Lacks tells the story of Henrietta Lacks. In the early 1951 Henrietta discovered a hard lump on the left of the entrance of her cervix, after having unexpected vaginal bleeding. She visited the Johns Hopkins hospital in East Baltimore, which was the only hospital in their area where black patients were treated. The gynecologist, Howard Jones, indeed discovers a tumor on her cervix, which he takes a biopsy off to sent it to the lab for diagnosis. In February 1951 Henrietta was called by Dr. Jones to tell about the biopsy results: “Epidermoid carcinoma of the cervix, Stage I”, in other words, she was diagnosed with cervical cancer. Before her first radium treatment, surgeon dr. Wharton removed a sample of her cervix tumor and a sample of her healthy cervix tissue and gave this tissue to dr. George Gey, who had been trying to grow cells in his lab for years. In the meantime that Henrietta was recovering from her first treatment with radium, her cells were growing in George Gey’s lab. This all happened without the permission and the informing of Henrietta Lacks. The cells started growing in a unbelievable fast way, they doubled every 24 hours, Henrietta’s cells didn’t seem to stop growing. Henrietta’s cancer cell grew twenty times as fast as her normal healthy cells, which eventually also died a couple of days after they started growing. The first immortal human cells were grown, which was a big breakthrough in science. The HeLa cells were spread throughout the scientific world. They were used for major breakthroughs in science, for example the developing of the polio vaccine. The HeLa-cells caused a revolution in the scientific world, while Henrietta Lacks, who died Octob...
At the time the tissue samples were collected from Henrietta Lacks she was an individual capable of deliberation about personal goals and of acting under the direction of such deliberation (Belmont Report, 1979). By collecting the samples without Henrietta’s sufficient consent she was denied of her freedom of choice. She was not given the opportunity for her decisions
Imagine that you were Douglas Mawson, along with two other explorers exploring unknown Antarctica, when everything goes wrong. Douglas Mawson suffered more adversity than Henrietta Lacks and Phineas Gage. Henrietta Lacks is about a woman who died from cervical cancer and her cells were extracted; later to find that her cells were immortal. Phineas Gage was a normal man when an extraordinary thing happened—he had a iron rod go through his skull. Phineas gage didn’t go through as much hardship, but he did go through more than Lacks. Half way through Mawson’s journey, both of his partners died, and it was just him, all alone in Antarctica. So, as anyone could see, Mawson experiences the most adversity among the three figures for many reasons.
People trust doctors to save lives. Everyday millions of Americans swallow pills prescribed by doctors to alleviate painful symptoms of conditions they may have. Others entrust their lives to doctors, with full trust that the doctors have the patient’s best interests in mind. In cases such as the Tuskegee Syphilis Experiment, the Crownsville Hospital of the Negro Insane, and Joseph Mengele’s Research, doctors did not take care of the patients but instead focused on their self-interest. Rebecca Skloot, in her contemporary nonfiction novel The Immortal Life of Henrietta Lacks, uses logos to reveal corruption in the medical field in order to protect individuals in the future.
In recounting Henrietta Lacks’ history, Rebecca Skloot in The Immortal Life of Henrietta Lacks, does not shy away from moral complexities such as informed consent and ethics. She uses narratives from Henrietta’s life to show how ethical wrongdoings of the hospital affected not only Henrietta’s existence, but her family’s. Text on the front and inside cover of Skloot’s book conveys this exact message, “Doctors took her cells without asking… Henrietta’s family did not learn of her ‘immortality’ until more than 20 years after her death, when scientists investigating HeLa began using her husband and children in research without informed consent. ” Throughout her book, Skloot skillfully analyses a real story of medical ethics by pointing out ironic situations and conveying her argument by an equal amount of
Rebecca Skloot’s novel, The Immortal Life of Henrietta Lacks, depicts the violation of medical ethics from the patient and researcher perspectives specifically when race, poverty, and lack of medical education are factors. The novel takes place in the southern United States in 1951. Henrietta Lacks is born in a poor rural town, Clover, but eventually moves to urban Turner Station. She was diagnosed and treated for cervical cancer at Johns Hopkins hospital where cells was unknowingly taken from her and used for scientific research. Rebecca Skloot describes this when she writes, “But first—though no one had told Henrietta that TeLinde was collecting sample or asked she wanted to be a donor—Wharton picked up a sharp knife and shaved two dime-sized pieces of tissue from Henrietta's cervix: one from her tumor, and one from the healthy cervical tissue nearby. Then he placed the samples in a glass dish” (33). The simple act of taking cells, which the physicians did not even think twice about, caused decades
The story about Henrietta Lacks is the evidence that the ethics of medical processes need to be improved. For a long time, many patients have been victims of malpractice. Sometimes, the doctors still can do anything without the agreement from patients. Any medical institution needs to hold the integrity on any consent form that is signed by a patient. To summarize, the story of Henrietta Lacks could be the way to improve the standardization and equality of medical institutions in the future.
Henrietta's Gynecologist Howard W. Jones,took a sample of the grape jello colored knot on her womb which turned out to be a tumor and later diagnosed her with cervical cancer. During her first treatment the doctors there ran many tests while henrietta laid unconscious on the operating table. The surgeon on duty,Dr.Lawrence Wharton jr., dilated her cervix and inserted radium inside of her cervix but no one told henrietta that they would be taking samples of her tissue from the tumor and her healthy cervical tissue without her knowledge. Her samples were later given to Dr.George Gey; George Gey was head of the tissue culture research at John Hopkins. Gey and his wife were trying to grow malignant cells outside of the body hoping to use them to cure cancer. She died at John Hopkins on October
Due to her cells being taken there have been a number of amazing discoveries and cures in the medical field, but it also brought pain and suffering for her family. The Lacks family was not even aware of Henrietta’s cells being taken, let alone that they were still alive and used in science. Of course Henrietta’s cells have helped to maintain sustainability within the human race by allowing there to be cures and medicine for all types of diseases and sickness; therefore the her cells being taken can be seen in a positive light.
In The Immortal Life of Henrietta Lacks Rebecca Skloot describes the case of John Moore, a man with Leukemia, who had his spleen removed. The doctor who did this surgery not only stole his cells but also sold them and made money off of them. The doctor did not inform John of his intentions. John’s cells now have a value of 3 billion dollars due to how valuable they are. When John found out about his doctor’s intentions he took to the doctor to court. The court informed John that everything the doctor did was under informed consent so it was found legal. The judge “rejected his suit because Moore did not have property interest in the cell line developed by his doctor and that his rights to privacy and dignity were sufficiently protected by doctrine of informed consent”(Devine) Today, due to that court case, patients who have any surgeries must sign a paper giving
Steinbock, Bonnie, Alex J. London, and John D. Arras. "’Rights- Based’ Approaches." Ethical Issues in Modern Medicine. Contemporary Readings in Bioethics. 8th ed. New York: McGraw-Hill, 2013. 23. Print.