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Dementia and its effects
Dementia and its effects
Dementia and its effects
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Alzheimer’s disease is relentlessly destroying the brains and lives of our nation’s older adults, robbing them of memory, the ability to reason, and affecting their emotions and behavior. Alzheimer’s disease is a degenerative disorder of the brain. The longer we live the greater the risk: one out of every two Americans aged 85 and older and one out of every 10 aged 65 and older are afflicted with the disease. It affects two groups of people: those with the disease and the loved ones who care for them. By the year 2050, an estimated 14 million Americans will be in its grip.
Alzheimer’s disease (AD) is a progressive disease of the brain, which is characterized by a gradual loss of memory and other mental functions. Alzheimer’s is the most common form of dementia -- a general term referring to loss of memory and the ability to think, reason, function, and behave appropriately. The word dementia is derived from two Latin words, which mean away and mind, respectively. It’s different from the mild forgetfulness normally observed in older people. Over the course of the disease, people with AD no longer recognize themselves or much about the world around them.
Alzheimer’s is marked by abnormal clumps, called senile plaques, and irregular knots, called neurofibrillary tangles, of brain cells. The plaque is an accumulation of an abnormal protein, amyloid. One theory regarding the cause of Alzheimer’s disease suggests that this plaque forms because the processes that normally operate to clear away this protein have become defective. Neurofibillary tangles are skeins of another abnormal protein, but the tangle is found inside the nerve cells. The reason why the tangles develop is not known, but the normal processing of protein by the cell seems to be disrupted. These tangles choke the nerve cells and prevent them for working properly. For reasons not well understood, these plaques and tangles take over healthy brain tissue, which devastates the areas of the brain associated with intellectual function.
There are a number of behaviors which may signal that a person might be in the beginning stages of Alzheimer’s disease. Here is a list of warning signs: (1) difficulty with familiar tasks, (2) slipping job performance, (3) language difficulties, (4) co...
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...ar the burden of caring for them. It is a slow, progressive disease with no known cure. As our population ages, Alzheimer’s is a tragedy that is affecting more and more people.
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Stem cells are a type of unspecialized cells that can revive themselves through the process of cell division (Abdel-Salam and Oma, 2011). They have a phenomenal potential to differentiate into other specific cell types in a living organism. These cells can also be activated to turn into organ-specific cells or tissues with defined activity but only under specific experimental set-up. Stem cells have the ability to remain as they are or divide further to renew deteriorated and damaged tissue cells. Recently it has been discovered that stem cells can be used to treat Alzheimer’s disease but still a lot of clinical trials are being conducted to find a specific government approved treatment. Alzheimer’s disease is the most common cause of dementia. The very first stages of Alzheimer’ include symptoms like confusion and using the right words while talking. As it gets on to later stages symptoms like loss of memory and mood swings start to appear (Begley et al., 2001). Any sort of stem cell treatment is not available to Alzheimer’s patients yet as researchers are still conducting new experiments. There are multiple neurons that get damaged by Alzheimer’s which makes the problem even more complex and different approach needs to be followed every time a clinical trial is conducted.
One of the good ways that Atlantic and Pacific worlds have impacted America was the Columbian Exchange. Columbus brought animals such as sheep’s, goats, horses, cattle all of which the Native Americans had never been introduced too. Columbus also brought new technology such as advancements in agricultural production, education and ware fare. He also brought plants such as potatoes, maize and sugarcane. All of these things were great and we still use them till today. The bad thing Columbus brought was diseases that helped kill Native Americans in mass numbers. Their body was not immune to such things as chicken pox, small pox and measles. We are still faced with these diseases today and have vaccination against such things. In the end the Columbian
Memory plays a significant role in the everyday lives of people of all ages. It allows them to recall information and remember skills that were learned in the past. Memory also organizes past information to help people make current and future decisions. However, imagine forgetting the names of close family members or not having the ability to find your keys every time you want to leave the house. These are some of the struggles that people with Alzheimer’s disease face daily. Alzheimer’s disease was first identified by German neurologist Alois Alzheimer in 1906, and was discovered to have an overpowering effect on explicit memory loss (Gruetzner, 1988). There are two types of Alzheimer’s disease – early onset and late onset. Early onset occurs in patients who are diagnosed before the age of 65 whereas late onset occurs in patients who are diagnosed after the age of 65. In the early stages of Alzheimer’s disease, short-term memory is often lost. As Alzheimer’s disease progresses, problems with long-term memory begin to develop, in addition to short-term memory impairments. Although a lot is known about the symptoms of Alzheimer’s disease, the cause has not been conclusively identified. However, as research continues, new theories about the cause of Alzheimer’s disease are being proposed. This has led to a controversy over whether Alzheimer’s disease is caused by genetics or environmental influences (Gruetzner, 1988).
performance that involves, but is not limited to, a loss in at least 2 of the
The sixth leading cause of death in the United States, Alzheimer’s disease afflicts approximately 5.2 million persons age 65 and over (Alzheimer's Association, 2012). Rapid growth of the older population as the Baby Boomer generation ages will cause unprecedented increases in the number of individuals with Alzheimer’s. It is estimated that by 2025 the number of Wisconsin residents with Alzheimer’s age 65 and older will increase by 30% to a projected total of 127,000 (Alzheimer's Association, 2012).
Alzheimer’s disease is a complex illness that affects the brain tissue directly and undergoes gradual memory and behavioral changes which makes it difficult to diagnose. It is known to be the most common form of dementia and is irreversible. Over four million older Americans have Alzheimer’s, and that number is expected to triple in the next twenty years as more people live into their eighties and nineties. (Johnson, 1989). There is still no cure for Alzheimer’s but throughout the past few years a lot of progress has been made.
Nerney, C. (2014, April). Dementia. Lecture conducted from Massachusetts’s College of Liberal Arts, North Adams, MA.
1) Loyalty- Stand up for the U.S. Constitution, the Army, your fellow Soldiers and the citizens you serve.
Alzheimer’s disease is a form of dementia which is a brain disorder that impairs mental functioning. Dementia attacks the part of the brain which controls memory, language, and thought. It makes everyday tasks like remembering to brushing your teeth, or to pay your bills next to impossible to do, which is why so many people who are diagnosed with this disease are in complete care. This disease has different phases, the first being slight forgetfulness and then the persons emotions may heighten as well as language impairment, violent outbursts, loss of bladder control and from there it keeps getting worse until complete dysfunction of the brain occurs and eventually death, which most of the time is the result of infection.
degeneration 3 A nerve cell has numerous axons and dendrites coming out of it. A neurofibrillary tangle is when the neuron changes. A number of dendrites are missing and the nucleus is filled with protein filaments resembling steel wool. Although all elderly people have a few of these helix shaped bundles in their brain as they are normal indicators of aging, Alzheimer's patients have. more than usual.
There are two abnormal structures called plaques and tangles, which are prime things in damaging and killing nerve cells. Plaques are deposits of a protein fragment called beta-amyloid, that builds up in the spaces between the nerve cells. On the other hand, tangles are twisted fibers of another protein called tau, that build up inside cells. Even though people develop plaques and tangles as they age, people with Alzheimer's disease, develop much more. People with Alzeimer's disease also develop plaques and tangles in a predictable pattern, starting in the areas important for memory, before spreading to other parts. Plaques and tangles will usually spread through the cortex as Alzheimer's progresses. It is believed that plaques and tangles play a critical role in blocking the communication among nerve cells and disrupting processes that cells need to
Although Columbus had the opportunity to work out an agreement and exist peacefully with the Native Americans, he was focussed on his mission to “find riches and conquer new lands.” The three main sources of controversy involving Columbus's interactions with the Native Americans are “the use of violence and slavery, the forced conversion of native peoples to Christianity, and the introduction of a host of new diseases that would have dramatic long-term effects. . .” These topics have been debated and mulled over for over five hundred years by many different historians.
There are three stages towards Alzheimer’s and one should be aware of the important signs and symptoms. For instance, one should be aware of co...
Alzheimer’s disease (AD) is a progressive, terminal, degenerative brain disease. It is the fourth leading cause of death in adults and currently affects over four million people in the United States. This number is expected to increase over the next several years as the baby boomers age, until it reaches fourteen million by the year 2025.