Aerosol Therapy Advantages And Disadvantages

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Aerosol Therapy: Traditional & New Drugs in Aerosol Medicine
Aerosol therapy in the past decade has evolved faster than its initial years after emerging as a primary form of treatment in respiratory diseases involving both congenital and acquired diseases. This type of inhalation therapy focuses on the delivery of the medications that have been directly or indirectly injected into the lower and upper airways for either local or systemic effects. The greatest advantage of aerosol therapy is the ability to treat patients with smaller doses which, over time, yields minimal adverse effects for non-specific drugs, along with being the most rapid in treatment response time. Modern aerosol medications are made to be compatible with certain devices, such as metered dose inhalers, dry powered inhalers, and nebulizers, each of which have certain advantages and disadvantages depending on appropriateness of delivery and treatment. The particle size of these different applicators are crucial in deciding the location in the body in which the drug is to be delivered.

An aerosol is a suspension of liquid or solid particles in a carrier gas. Aerosol therapy is the delivery of an aerosol drug to the body via the airways by delivering it in an aerosolized form. The advantages of this form of drug delivery is that …show more content…

The key mechanisms that affect pulmonary depositions of aerosols are inertial impaction, sedimentation and diffusion. These three mechanisms operate within a range of various combinations when certain aerosol drugs that affect different areas within the lung are used. Inertial impaction occurs when a large particle size aerosol, usually three microns and over, are inhaled and settled at the process of the oropharynx and larger airways. Aerosols that are smaller in size diffuse within the lower airways, making it the dominant mechanism if the aerosol particles make it

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