The Factor of War in the Development of Penicillin

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The Factor of War in the Development of Penicillin

The discovery, development and subsequent use of penicillin can be

considered to be one of the most important breakthroughs in medical

history. There were many factors, which were involved in the

development of penicillin, and it could be argued that war was the

most important, but other factors were also responsible.

Alexander Fleming was working in London as a bacteriologist in 1928

when he noticed that a growth of a mould called penicillin produced a

substance that actually killed the germs he was working on. He

realised that this might be very important and a year later he wrote

an article about his findings. However, Fleming did not have the

facilities or the support to develop and test his idea that penicillin

could fight infection, and he didn't develop it further. This was a

factor that was based on chance, as the penicillin (mould) had

probably blown through a window. In my opinion Fleming didn't have

much do to with the development of Penicillin, but he did recognise

its importance and published his findings.

Florey and Chain were scientists. They stumbled across Fleming's

research papers and were intrigued by his findings. They were sure

that, if Fleming was right, this discovery could save a lot of lives,

prevent pain and make it much easier to fight infectious diseases and

prevent other infections. Florey and Chain developed a system of

growing penicillin: which was complicated initially, and tested its

effectiveness on mice. The tests were successful and the two men

became convinced that the drug would cure many people who would

otherwise die.

Florey and Chain were unable to expand on the development of the drug,

as mass production was not financially feasible at the time. In June

1941, Florey travelled to America to try and interest drug companies

there in developing penicillin. Due to the bombing of Pearl Harbour,

the United States became involved in the Second World War. Once

involved in the conflict, the Americans were easily persuaded to

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