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Hypertension etiology and pathophysiology
Examine causes of hypertension essays
Examine causes of hypertension essays
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Describe the pathophysiology of essential hypertension.
The pathophysiology of essential hypertension rests on the characteristic finding that there is an inappropriate increase in peripheral vascular resistance, as related to the cardiac output. Usually this occurs without without any cause being evident. This is possible due to the change in small arteries where the media/lumen ratio rises. Still it is not clear whether this is a cause or consequence of hypertension. The conduit of large arteries like the aorta becomes stiffer, also influences hypertension. Basically there have been no findings on the root cause of hypertension.
What are some risk factors that may affect patients?
There are multiple risk factors: genetics – if there
High Blood Pressure is anything that alters in peripheral vascular resistance, heart rate, or stroke volume that affects systematic arterial blood pressure. Long term effect of high blood pressure are serious and can cause heart attacks, strokes, kidney failure, and retinal damage. Hypertension is another medical word that substitutes the meaning of high blood pressure. It is known as the “silent killer” because it does not create any symptoms. The most common reason for high blood pressure is arteriosclerosis. Arteriosclerosis is the thickening and hardening of the walls of the arteries, occurring in old age. Four control systems have a job in maintaining blood pressure. These are the arterial baroreceptor and chemoreceptors’ system, regulation of body fluid volume, the renin- angiotensin system, and vascular autoregulation. Primary hypertension mostly occurs from a defect or malfunction in some or all of these
Chronic hypertension leads to atherosclerosis (plaque build-up) which causes the walls of the arteries to harden and in turn can lead to blockage/clots.
Blood pressure is a measurement of the force against the walls of your arteries as your heart pumps blood through your body. Hypertension is another term used to describe high blood pressure. This common condition increases the risk for heart disease and stroke, two leading causes of death for Americans. High blood pressure contributed to more than 362,895 deaths in the United States during 2010. Approximately 67 million persons in the United States have high blood pressure, and only half of those have their condition under control. An estimated 46,000 deaths could be avoided annually if 70% of patients with high blood pressure were treated according to published guidelines (Patel, Datu, Roman, Barton, Ritchey, Wall, Loustalot; 2014).
The causes of hypertension are unknown. However; hypertension can be classified into two categories primary and secondary. Primary (essential) hypertension is increas...
Hypertension, also known as high blood pressure is a medical condition where the arteries are constantly experiencing high blood pressure due to the force exerted on the walls of the arteries as the heart pumps blood throughout the body.
Other studies have attempted to measure the effect of distance on blood pressure response in order to find if there is any correlation between distance and a significant blood pressure reduction. One of these studies (see Moreau et al, 2001) involved 24 sedentary post-menopausal American women (15 in the intervention group ) with high blood pressure. The results found that, after a 2-year walking programme, that there was a statistically significant drop of 13 mmHg in the systolic blood pressure of those participants who were taking anti-hypertensive drugs and of 11 mmHg in those not receiving medication, whereas there was no difference found in their diastolic blood pressure and in the blood pressure of the control group. The participants in the intervention group were instructed to walk 3 kms per day in addition to their normal daily physical activity. After the first year the reduction in blood pressure was significant: 6 mm Hg in the systolic blood pressure of the participants who were taking anti-hypertensive medication and 7mmHg in the non-medication group.
Hypertension is one of the major risk factors for the development of cardiovascular diseases including stroke and may also have a role in the development of vascular cognitive impairment and vascular dementia [1, 2]. Angiotensin I-converting enzyme (EC 3.4.15.1; ACE) plays an important role in the rennin-angiotensin system and it is a carboxyl-terminal dipeptidyl exopeptidase that catalyzes the conversion of angiotensin I to angiotensin II [3-6]. ACE converts an inactive form of decapeptide, angiotensin I, to a potent vasoconstrictor, octapeptide, angiotensin II, in addition; since the ACE is a multifunctional enzyme it also catalyzes the degradation of bradykinin, which is known as a vasodilator [4, 7]. Therefore, inhibition of ACE activity leads to decrease in the concentration of angiotensin II and increases the level of bradykinin; consequently reduce blood pressure [8].
The leaflet “Blood pressure” by British Heart foundation, issued September 2001 7. The website http://www.lifeclinic.com/focus/blood/articleView.asp?MessageID=579 8. The website http://www.bbc.co.uk/schools/16/sosteacher/biology/32764.shtml 9. The website http://www.reutershealth.com/wellconnected/doc14.html
Hypertension also known simply as high blood pressure is a common problem related to heart disease. When a person has high blood pressure, the heart has to work harder. It also speeds up the hardening of the arteries (atherosclerosis). Although high blood pressure cannot be cured, it can be controlled with a healthy diet, exercise and if necessary medication
There are so many complex factors for high blood pressure. There are environmental factors. There are genetic factors. Even race plays a huge role in what type of blood pressure is natural for that specific race. You would be amazed of how many factors are in a human being having high or low blood pressure. The traits in having high blood pressure are so complex. And what is amazing about all of these traits and environmental factors is that they are all linked together in a way. And in this essay I will explain how these traits, environmental factors, and even race are all linked in a certain complex way.
There are generally two categories of hypertension, primary hypertension and secondary hypertension. The causes of primary hypertension are usually unknown and it develops gradually over the years. As for secondary hypertension, the causes are mainly underlying other health problems and it develops in a sudden of time. (The Healthline Editorial Team 2013) First of all, hypertension can be related to renin-angiotensin-aldosterone system (RAAS). Renin is an enzyme secreted mainly via the juxtaglomerular apparatus of the kidney when the sodium retention and water retention are reduced in the blood. (Beevers, Lip, and O'Brien 2001) Renin will bind to a substrate which is angiotensinogen and form angiotensin I which is an inactive peptide. (Foëx and Sear 2004) After that, angiotensin I will be rapidly converted to an active peptide angiotensin II by angiotensin-converting enzyme (ACE) in lungs. As a result, vasoconstriction occurs due to presence of angiotensin II and this increases the blood pressure. Moreover, angiotensin II can stimulate the releasing of aldosterone by adrenal glands. Secretion of aldosterone raises the blood pressure by reabsorbing sodium salts and water to increase sodium and water retentions. (Beevers, Lip, and O'Brien 2001)
Cardiovascular disease is currently the nation’s leading non-communicable cause of morbidity and mortality. According to the American Heart Association, the most common form of cardiovascular disease is coronary artery disease, a condition in which the heart’s blood supply is reduced due to a narrowing of the coronary arteries. These arteries play a significant role in regulating the flow of oxygenated blood to the heart. As blood circulates through the arteries, it exerts a force against the vessel walls, known as blood pressure. To withstand this pressure, elastic fibers interspersed along the artery walls allow the arteries to expand and recoil. Abnormally high blood pressure, however, will cause these muscles to thicken as a result of tears in the damaged artery walls trapping particles that aggregate as plaque. Progressive build-up of plaque ultimately leads to a narrowing of the arteries, subsequently diminishing blood flow to the heart and other body organs. This cascade of events triggered by high blood pressure illustrates why hypertension is one of the most important risk factors for cardiovascular disease. Affecting 1 in every 3 adults in the United States alone, hypertension substantially raises the risk for heart disease in an affected individual who, most likely, does not show any signs or symptoms. In addition to the risks associated with this “silent killer,” comorbidities such as obesity, diabetes, and high cholesterol can drastically worsen health outcomes in hypertensive patients. Given the high prevalence and severe consequences of hypertension if undetected, researching this particular topic will increase our understanding of the causes of hypertension by identifying and narrowing down lead candidates for pot...
Vicki is a 42-year-old African American woman who was diagnosed with Hypertension a month ago. She has been married to her high school sweetheart for the past 20 years. She is self-employed and runs a successful insurance agency. Her work requires frequent travel and Vicki often has to eat at fast food restaurants for most of her meals. A poor diet that is high in salt and fat and low in nutrients for the body and stress from her job are contributing factors of Vicki’s diagnosis of hypertension. This paper will discuss the diagnostic testing, Complementary and Alternative Medicine treatments, the prognosis for hypertension, appropriate treatment for Vicki, patient education, and potential barriers to therapy that Vicki may experience.
Works Cited: Kanbar, R. (2015, January 29). Disorders of the cardiovascular system: hypertensive vascular disease. Lebanese American University School of Pharmacy Retrieved from PHA210, Systems Pathophysiology Lecture Handout.
Hypertension, according to the mayoclinic, is a condition where your heartbeats blood through your arteries with a high magnitude of force, which can eventually lead to heart problems due to damaged arteries and blood vessels.