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Literature review on bronchiolitis
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Literature review on bronchiolitis
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What is bronchiolitis? Bronchiolitis is an inflammatory respiratory condition. It’s caused by a virus that affects the smallest air passages in the lungs. The job of the bronchioles is to control airflow in your lungs. When they become infected or damaged, they can swell or become clogged. This blocks the flow of oxygen. Although it’s generally a childhood condition, bronchiolitis can also affect adults. There are two types; Viral bronchiolitis, and bronchiolitis obliterans. Viral bronchiolitis is more common and can occur during the winter time and only in infants. This type happens because of respiratory syncytial virus. Bronchiolitis obliterans is a very rare and very dangerous condition that is only seen in adults. This blocks the air passages creating an airway obstruction that can’t be reversed. …show more content…
The infection makes the bronchioles swell and become inflamed. Mucus collects in these airways, which makes it difficult for air to flow freely in and out of the lungs.
Most cases of bronchiolitis are caused by the respiratory syncytial virus (RSV). RSV is a common virus that infects just about every child by the age of 2. Outbreaks of the RSV infection occur every winter. Bronchiolitis can also be caused by other viruses, including those that cause the flu or the common cold. Infants can be reinfected with RSV because at least two strains exist.
The viruses that cause bronchiolitis are easily spread. You can contract them through droplets in the air when someone who is sick coughs, sneezes or talks. You can also get them by touching shared objects — such as utensils, towels or toys — and then touching your eyes, nose or
Bronchospasm is an abnormal contraction of the smooth muscle of the bronchi, narrowing and obstructing the respiratory airway, resulting in coughs, wheezing or difficulty in breathing. The chief cause of this condition is asthma, although it may also be caused by respiratory infection, chronic lung disease or an allergic reaction to chemicals. The mucosa lining of the trachea may become irritated and inflamed, which secretes mucus, causing it to be caught in the bronchi and triggers coughing.
Croup: Croup is another common airway inflammation caused by virus that can affect the trachea, larynx and possibility the bronchi (Murray, Sidani, & Zoorob, 2011) thus causing infection in the upper respiratory tract. Murray et al. describes it as the most common illness in children under the age of 6 to 36 months and cause for cough mostly when a child cries; acute stridor and hoarseness in febrile children (Murray et al., 2011). It can be a life-threatening situation in the life of the young infant and the family. Croup symptoms exhibit as hoarseness, barking cough, inspiratory stridor, and respiratory distress. I chose this diagnosis as my first preference because when I read the mother’s subjective report it matches that of croup symptoms: a barking cough, no fever, severe at night and when the baby cries, fatigue due to excessiveness of the tears, pain due to inflames and swollen of the airway. Murray et al., led us to understand that the etiologies of this viral causing agent can be traced to the parainfluenza viruses, type 1. (2011). This virus is commonly spread through contact or droplet secretion.
To better understand how COPD affects an individual you should first know how the lungs function. When you breathe in air it first goes through your trachea then into your bronchioles. Once in the bronchioles the air goes to the air sacs called alveoli. In the alveoli, the gas exchange occurs with the capillaries. Gas exchange is when the oxygen enters the bloodstream and carbon dioxide enters the alveoli. During the breathing process, alveoli will inflate when inhaling and deflate while exhaling.
My disease is Streptococcal pneumonia or pneumonia is caused by the pathogen Streptococcus pneumoniae. Streptococcus pneumoniae is present in human’s normal flora, which normally doesn’t cause any problems or diseases. Sometimes though when the numbers get too low it can cause diseases or upper respiratory tract problems or infections (Todar, 2008-2012). Pneumonia caused by this pathogen has four stages. The first one is where the lungs fill with fluid. The second stage causes neutrophils and red blood cells to come to the area which are attracted by the pathogen. The third stage has the neutrophils stuffed into the alveoli in the lungs causing little bacteria to be left over. The fourth stage of this disease the remaining residue in the lungs are take out by the macrophages. Aside from these steps pneumonia follows, if the disease should persist further, it can get into the blood causing a systemic reaction resulting in the whole body being affected (Ballough). Some signs and symptoms of this disease are, “fever, malaise, cough, pleuritic chest pain, purulent or blood-tinged sputum” (Henry, 2013). Streptococcal pneumonia is spread through person-to-person contact through aerosol droplets affecting the respiratory tract causing it to get into the human body (Henry, 2013).
Haas, D. F. (1990). The Chronic Bronchitis And EMPHYSEMA. New York,NY: John Wiley and Sons, Inc.
Cystic Fibrosis is an inherited disease characterized by the buildup of thick, sticky mucous that can cause severe damage to the body’s organs. Mucous is usually a slippery substance that lubricates and protects the linings of the airway, digestive system, reproductive system and other organs and tissue. Problems with digestion can lead to diarrhea, malnutrition, poor growth, and weight-loss. Due to the abnormally thick mucous it can can clog airways, leading to breathing problems and bacterial infections in the lungs. Bacterial infections can lead to coughing, wheezing and inflammation. Overtime these infections can lead to permanent damage in the lungs including the formation of scar tissue, known as fibrosis and cysts in the lungs (Genetics Home Reference, 2013). The symptoms and signs of this disease vary but mostly include progressive damage to the respiratory system and chronic digestive system problems. An individuals’ lungs who are infected by cystic fibrosis have bacteria from an early stage. This bacteria can spread to the small airways, leading to the formation of bacterial micro-environments known as biofilms. Biofilms are difficult for antibodies to penetrate, therefore the bacteria repeatedly damage the lung and gradually remodel the airways, resulting in difficultly to eradicate the infection (Welsh, 1995). Cystic fibrosis patients may even have their airways chronically colonized be filamentous fungi and/or yeasts. Most men with cystic fibrosis have congenital bilateral absence of the vas deferens (CBAVD), a condition in which the tubes that carry sperm are blocked by mucous and do not develop properly. As well, women may experience complications in pregnancy. Either the c...
The bacteria are gasped in a process of air and overcome by alveolar macrophages. In some cases the bacteria’s are able to reproduce and the new pledge can harm the victim. Furthermore, Tuberculosis spreads when the mycobacterial enters alveolar mycobacterial.
My hypothesis on Tuberculosis is that it is a very deadly disease that causes a persons lungs to fill with blood. This can harm the body by making the body suffocate itself when the lungs fill with blood.
Liam is a previously healthy boy who has experienced rhinorrhoea, intermittent cough, and poor feeding for the past four days. His positive result of nasopharyngeal aspirate for Respiratory Syncytial Virus (RSV) indicates that Liam has acute bronchiolitis which is a viral infection (Glasper & Richardson, 2010). “Bronchiolitis is the commonest reason for admission to hospital in the first 6 months of life. It describes a clinical syndrome of cough tachypnoea, feeding difficulties and inspiratory crackles on chest auscultation” (Fitzgerald, 2011, p.160). Bronchiolitis can cause respiratory distress and desaturation (91% in the room air) to Liam due to airway blockage; therefore the infant appears to have nasal flaring, intercostal and subcostal retractions, and tachypnoea (54 breathes/min) during breathing (Glasper & Richardson, 2010). Tachycardia (152 beats/min) could occur due to hypoxemia and compensatory mechanism for low blood pressure (74/46mmHg) (Fitzgerald, 2011; Glasper & Richardson, 2010). Moreover, Liam has fever and conjunctiva injection which could be a result of infection, as evidenced by high temperature (38.6°C) and bilateral tympanic membra...
...are methods of treatment that can alleviate the severity of the symptoms that come with bronchitis and emphysema. First of all, there are corticosteroids. Corticosteroids can be inhaled, injected, or consumed orally as a pill. They reduce the inflammation of airways, making breathing easier. For acute flares of bronchitis, they are usually injected or given as a pill. Inhalants are often prescribed for daily use because they are effective and are easier to take than injections, which is needed for patients with chronic bronchitis, for those patients fight day to day battles with breathing. Another method of treatment is the use of antibiotics. These are mostly used for acute flare-ups, however, as has previously been discussed, there are many issues regarding the proper distribution and use of antibiotics, and resistance to antibiotics can occur easily and rapidly.
An asthma attack has many effects on the body. Asthma affects the body by limiting the flow of air into the lungs. It causes airway inflammation, bronchial restriction and irregular airway obstruction. Airway inflammation is how the body reacts to something that is irritating the airways. When happening your lungs begin swelling, your breathing passageway becomes restricted and mucus is secreted. Bronchial restriction happens when the muscles in your airways tighten around the breathing tubes in your lungs. (Bronchial tubes). Mucus or fluid that is accumulated by the reaction can obstruct your airway and make it very difficult to breathe properly.
The leading cause of death in America is lung cancer. Lung cancer is ranked top 10 fatal cancers in the United States. There are many types of ways to get lung cancer. There is radon gas it occurs outdoors naturally. Then there is second hand smoke that comes from other people smoking. People are even getting lung cancer from cancer causing agents, this happens from carcinogens. You can also get it from air pollution indoors and outdoors. Also there are gene-mutations that form cancer causing cells. Then there is the one everyone blamed lung cancer is smoking.
Air then travels to the bronchioles which are narrow (bronchoconstriction) due to the natural defence in keeping irritants out of the airway, causing wheezing breath sounds.(Eldridge, 2016) The air then proceeds to the alveoli, which are weakened and damaged air sacs due to the progression of the disease, that are unable to efficiently move O2 into the blood stream and gas exchange CO2 to be expelled through exhale, causing hypoxemia, lethargy, dyspnoea and high CO2 reading. (“Lung conditions - chronic obstructive pulmonary disease (COPD),”
Chronic bronchitis is a disorder that causes inflammation to the airway, mainly the bronchial tubules. It produces a chronic cough that lasts three consecutive months for more than two successive years (Vijayan,2013). Chronic Bronchitis is a member of the COPD family and is prominently seen in cigarette smokers. Other factors such as air pollutants, Asbestos, and working in coal mines contributes to inflammation. Once the irritant comes in contact with the mucosa of the bronchi it alters the composition causing hyperplasia of the glands and producing excessive sputum (Viayan,2013). Goblet cells also enlarge to contribute to the excessive secretion of sputum. This effects the cilia that carry out the mechanism of trapping foreign bodies to allow it to be expelled in the sputum, which are now damaged by the irritant making it impossible for the person to clear their airway. Since the mechanism of airway clearance is ineffective, the secretion builds up a thickened wall of the bronchioles causing constriction and increasing the work of breathing. The excessive build up of mucous could set up pneumonia. The alveoli are also damaged enabling the macrophages to eliminate bacteria putting the patient at risk for acquiring an infection.
There are 5 main pathways of environmental transmission of pathogens. Those are air-borne, food-borne, water-borne, vector-borne and blood-borne. Air-borne transmission refers to any disease that is caused by a pathogen and transmitted through the air. These pathogens can be spread by coughing, sneezing, stirring dust, liquid spraying, or generally any activity that generate aerosol particles or droplets. These pathogens can include viruses, bacteria, or fungi. Some common examples of pathogens that are spread via air-borne transmission are rhinovirus, hantavirus, adenovirus, and influenza, among many others (cdc.gov).