Dementia is defined by the World Health Organization as a syndrome due to damage of the brain cells that most often chronic and progressive in nature. Some of the cortical functions that become impaired include memory, thinking, orientation, comprehension, calculation, learning capacity, language and judgment. Other manifestations that may accompany this disease are deterioration in emotional control, social behavior or motivation (Ouldred & Bryant, 2009) Dementia is not a normal part of aging, however it occurs most frequently in the older population. Fifteen percent of Americans over the age of sixty-five have dementia, and as the average life span continues to increase, so will the number of those affected by dementia (Fredman, James, Johnson, Scholz, & Weuve, 2012). The purpose of this paper is to discuss the pathophysiology, risk factors, symptoms, and treatment options for different types of dementia.
Literature Review
Alzheimer’s Disease
Alzheimer’s disease is the leading cause of dementia, affecting approximately 5.3 million Americans (Lewis, Dirkenson, Heitkemper, Bucher, & Camera, 2011). This disease is characterized by abnormal amyloid plaques and neurofibrillary tangles that develop within the brain. This causes brain cells to die and leads to a reduction of chemicals in the brain, specifically acetylcholine (Ouldred & Bryant, 2009).
Risk factors for this disease include age, genetics (ApoE variation), diabetes mellitus, smoking, and depression. Alzheimer’s has also been associated with lower socioeconomic status and education level, and poor access to health care. Women are more likely to develop Alzheimer’s disease than men because women tend to have a longer life span (Lewis et al., 2011).
Those with dementia diff...
... middle of paper ...
...vels decrease, the brain cannot create enough energy to work properly. This is a chronic disorder accompanied by severe memory impairment, while other thinking and social skills may remain intact (“Types of Dementia” n.d.).
Conclusion
As our aging population increases, so will the number of people who develop dementia. This condition is distressing for everyone involved, including the patient, family, and caregiver. As research continues, there is hope for a better quality of life for those affected. It is important to increase awareness, encourage prevention, and to be aware of the early signs and symptoms. Each case of dementia presents itself differently, so it is important to know there are different types of dementia along with slightly different signs and symptoms. The sooner dementia can be recognized and intervened, the greater the outcome for the patient.
Dementia is common among a large population of elderly people. The disease affects not only the individual diagnosed, but also the caregivers that work towards making their life comfortable in the end. Understanding and learning about the disease is crucial in helping those that experience or live with someone who has dementia. The services and support that are currently in affect for elderly people with dementia and the caregivers is poor, and ineffective because of the lack of research and information on the topic.
While the average life expectancy of the world’s population has increased, the number of detected dementia cases has commensurately risen to astonishing levels. Along with improved discovery of this disorder, new causes and treatments have been found, from which many innovative techniques have been developed towards the prevention of future incidences and reduction of the effects of this condition; however, the quest for these solutions have raised more questions than it has answered. Why do some develop this disorder, while others do not? Can early detection be achieved to reverse the processes or limit its effects? Further specifics on these topics have been categorized into three main sections, which include:
People with dementia may have problems with short-term memory, keeping track of their belongings, keeping up with plans, remembering appointments or travel dates. Many dementias are progressive. This means that symptoms start out slowly and gradually get worse with time. Alzheimer’s and other types of dementia are diagnosed based on careful medical history, a physical examination, laboratory tests, and the characteristic changes in thinking, day-to-day function and behavior related to each
Alzheimer’s disease is a complex illness that affects the brain tissue directly and undergoes gradual memory and behavioral changes which makes it difficult to diagnose. It is known to be the most common form of dementia and is irreversible. Over four million older Americans have Alzheimer’s, and that number is expected to triple in the next twenty years as more people live into their eighties and nineties. (Johnson, 1989). There is still no cure for Alzheimer’s but throughout the past few years a lot of progress has been made.
Dementia is a significant health issue in Australia (Australian Institute of Health and Welfare 2012) (AIHW 2012). Whilst Dementia primarily affects older members of the community, it can also affect young people and has a significant influence on overall health and quality of life (AIHW 2012). The type of Dementia is a determinant in the severity and development of symptoms in individuals (Department of Health 2013) (DoH, 2013). The gradual, progressive and irreversible nature of Dementia has a considerable social and physical impact not only on the individual, but also on family and friends.
Nerney, C. (2014, April). Dementia. Lecture conducted from Massachusetts’s College of Liberal Arts, North Adams, MA.
Dementia is the progressive deterioration and impairment of memory, reasoning, and other cognitive functions occurring as the result of a disease or condition. Dementia can affect the person’s ability to carry out daily activities. For example, the person may forget where they live or they might think they have already done their activities but never did. Dementia can also cause the elderly to become incontinent and can’t control their urinary system. Many people get confused that dementia is a disease. Dementia is not a disease. However, it can lead to a disease or condition. Dementia is more common in the elderly population. It’s normal for people to forget things, but to a certain extent it becomes a critical issue. Depression also plays a role in the affects of dementia. Studies have been made to believe that the biological mechanisms for depression relating to dementia is, “interactions with vascular diseases, changes in glucocorticoid steroid levels that can result in hippocampal atrophy, accumulation of amyloid-[beta] plaques, inflammatory processes, and lack of nerve growth factors” (Heser et al., 2013). Dementia is caused because of plaques and neurofibrillary tangles. This can also be known as Alzheimer’s Disease. Dementia is the leading cause for Alzheimer’s Disease in the elderly. For all dementia cases, 60 to 80 percent of people with dementia will have Alzheimer’s Disease. The disease has 3 different stages, the early stage, the middle stage, and the late stage. Each of those stages has a variety of symptoms that affects the memory impairment of the person (Wieregna, Bondi, 2011). Also relating to dementia is Parkinson’s Disease and Huntington Disease. These diseases can result in impairment, which can cause challeng...
Dementia is an acquired clinical disorder that affects loss of brain cells, causing a gradual onset and the continued decline of higher cognitive functioning. This damage interferes with how parts of the brain cells communicate with one another. It affects memory, thinking, language, judgment, and behavior. Dementia is classified in two categories: reversible and irreversible. Reversible dementia can be the result of a medication reaction, metabolic disturbances, emotional distress, infections, and nutritional deficiencies. These, however, are treatable and should be identified early if suspected to avoid lasting side effects. Unlike degenerative (irreversible) dementia, it is common to any age group. Irreversible dementia is the broadened classification for Alzheimer’s, Parkinson’s, and Huntington’s disease. These tend to only affect the older population, people over sixty-five. As the disease worsens, people have problems with short-term memory loss, like forgetting things they have said or done, even though they can often recall events that happen...
“…a group of symptoms that are caused by changes in brain function. Dementia symptoms may include asking the same questions repeatedly; becoming lost in familiar places; being unable to follow directions; getting disoriented about time, people, and places; and neglecting personal safety, hygiene, and nutrition. People with dementia lose their abilities at different rates.”
Alzheimer's disease is the most common form of dementia, and this terminal, progressive brain disorder has no known cause or cure. Its greatest known risk factor is increasing age which is why is it is infamous for developing in the elderly, typically in ages 65 or over, however for the 5%(1) that develop Alzheimer’s in their 40s or 50s it is known as early Alzheimer’s. Because Alzheimer’s worsens over time, those with it tend to struggle with completing daily tasks especially elderly people. Given that there is no cure for Alzheimer’s, the treatments available slow the worsening of dementia symptoms and improve quality of life for those with Alzheimer’s and their caregivers. It is not known what causes Alzheimer's, however, those with Alzheimer's have been found to have abnormal amounts of protein (amyloid plaques) and fibres.(The amyloid plaques and fibres are found in regions of the brain where problem solving and thinking take place e.g The cerebrum.) Due to the unusual amounts of amyloid plaques and fibres, it reduces the effectiveness of healthy neurons and eventually, destroying them.
In 1906, a German physician named Dr. Alois Alzheimer dealt with a patient that had been battling severe memory and confusion problems and had tremendous difficulty understanding questions and basic functions. Alzheimer suspected that the ailment had more to it than inherent memory loss. During an autopsy of the brain, he discovered that there were deposits of neuritic plaques surrounding the nerve cells and twisted fibers, known as neurofibrillary tangles, inside of the nerve cells. These observations became the definitive diagnosis of Alzheimer’s disease. The plaques and tangles that develop are a natural part of aging; however, they develop far more aggressively in Alzheimer’s victims. The plaques and tangles then block communication among nerve cells and disrupt the cells processes, eventually killing them. This destruction causes memory failure, personality changes, and problems carrying out everyday functions. Alzheimer’s especially attacks the memory. A victim in the later stage of the disease can...
Dementia is a long-term condition that normally affects people aged 65 and over, younger people can be affected. Having dementia can cause loss of key functions to the brain, such as; loss of memory; confusion; speech and language problems; loss of ability to make judgements; loss of concentration; difficulty in processing information; changes in behaviour and personality. These all lead to a person not been able to function properly. The person’s ability to function deteriorates over a period of time and is usually at least 6 months before positive diagnosis of dementia can be made. Dementia is caused when the brain is damaged by diseases such as Alzheimer’s which is the most common of dementia, vascular which is a series of mini strokes,
Alzheimer’s disease or AD is an incurable disorder of the brain that results in loss of normal brain structure and function. In an AD brain, normal brain tissue is slowly replaced by structures called plaques and neurofibrillary tangles. The plaques represent a naturally occurring sticky protein called beta amyloid and in an Alzheimer’s brain, sufferer’s tend to accumulate too much of this protein. Neurofibrillary tangles represent collapsed tau proteins which, in a normal brain along with microtubules, form a skeleton that maintains the shape of the nerve cells. In Alzheimer’s disease, the tau proteins break loose from their normal location and form tangles. Without the support of these molecules, nerve cells collapse and die. As normal brain structure is lost with progression of the disease, brain function also degenerates. Patients afflicted with Alzheimer’s disease display a gradual mental decline. Initially, and most apparently, there is a loss of short-term memory. Eventually, as a patient progresses to later stages of the disease, the brain becomes so damaged that patients can no longer communicate or recognize immediate family or even themselves. They have difficulty walking and standing and frequently fall. In the final stages, they lose bladder and bowel control and have difficulty with swallowing, frequently leaving them malnourished and dehydrated. Eventually, they are forced to remain bedridden and, without the help of life-prolonging measures provided in a hospital, die. However, this level of deterioration is severe and may take as long as twenty years. Because of the disease’s slow progress and its usual later start in a person’s life, a victim of AD will usually die first of natural causes. Under the objectives ...
Dementia is an organic brain syndrome which results in global cognitive impairments. Dementia can occur as a result of a variety of neurological diseases. Some of the more well known dementing diseases include Alzheimer's disease (AD), multi-infarct dementia (MID), and Huntington's disease (HD). Throughout this essay the emphasis will be placed on AD (also known as dementia of the Alzheimer's type, and primary degenerative dementia), because statistically it is the most significant dementing disease occurring in over 50% of demented patients (see epidemiology).
Alzheimer’s Disease is named after a German doctor, who specializes in the brain and nervous system, named Alois Alzheimer. This Disease forms in the brain. Alzheimer’s is the most common form of Dementia, a general term for memory loss and other intellectual abilities serious enough to enter. The Tau protein ensures the tubes in your brain stay straight allowing molecules to pass through freely. In Alzheimer’s Disease the protein collapses into strands or tangles, making the tubes disintegrate. There is visible differences of brain tissue in the from misfolded proteins called plaques and tangles. Beta-Amyloid clumps block signals and communication between cells in the brain. Researchers agree that Alzheimer’s Disease is m...