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Define homeostasis as it relates to human health
Acute renal failure pathophysiology
Acute renal failure pathophysiology
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Recommended: Define homeostasis as it relates to human health
Homeostasis defines how the body regulates a constant optimal condition and this is regulation is achieved through mechanisms such as receptors, the control centre and effectors. Whilst Dan exercises, he will notice a marked increase in his breathing and heart rate as the hypothalamus detects changes in the blood and communicates this though to his medulla via a chemical messenger that binds and stimulates the receptors on postganglionic neurons found in the spinal cord. In response, Dan’s medulla, which controls heart rate, will release epinephrine and norepinephrine into the blood, which then travel to his heart in order to stimulate the sinus node. Once this occurs the electrical signals from the sinus will become stronger, prompting stronger …show more content…
contractions from the heart in order pump oxygenated blood faster around the body to aid in the production of ATP for aerobic respiration. Regulations for blood sugars are now needed as ATP requires oxygen to initiate sustainable energy through glycolosis. If this doesn’t happen the body will no longer be able to sustain exercise and will seize from exhaustion. This increase in heart rate also ensures efficient removal of waste products such as carbon dioxide and excess heat which is also carried away from the muscles in the blood and brought to the surface of the skin, where it is expressed through the pores as sweat, in order to regulate the temperature of the body.
When this doesn’t happen, the body can overheat and various health complaints can occur, such as swelling and fainting. Dan’s breathing rate is controlled by the respiratory control centre of the brain, this recognises levels of oxygen and carbon dioxide in the blood and responds
When exercise ceases, Dan’s muscles will signal the medulla to release acetylcholine. This slows down the contractions of the heart, and allows the heart to rest by reducing the heart rate. Ultimately homeostatic function is regulated by the sympathetic and parasympathetic nervous system of which both are part of the autonomic nervous system. The temperature of the body is regulated by the thermoregulatory centre located within the hypothalamus. Two receptors work together to maintain the homeostatic ideal and these are an internal one located within the brain, and an external receptor that is skin. An example of homeostatic maintenance is vasodilatation which occurs when the body’s internal temperature is too high. This
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process relaxes the muscle of blood vessels so that a larger volume of blood can be transported closer to the skins surface. In order to conduct all energy production within the body, glucose must be present. This is stored at a cellular level as glycogen and is commonly found in the liver. During the anaerobic phase of Dan’s exercise he will use up the small stores of glucose with his blood and skeletal muscle, but as his exercise continues a process called glycolysis must take place within the liver in order to break down glycogen to glucose ready to be transported and used in order to maintain production of ATP. This is achieved through the use of the hormones glucagon and insulin and they work together to regulate the production and transportation of glucose into the bloodstream. The body breaks down food and takes the required nutrients away and uses then for anabolism and energy production. After this has occurred there are many waste products that are left within the body. The main function of the urinary system is to process and filter blood to remove toxins such as urea whilst ensuring the correct levels of salts, potassium and water are within homeostatic levels. Another vital function of the kidneys and urinary system include blood pressure regulation through the use of the anti-diuretic hormone. Kidneys also produce cells called erythropoietin. These monitor and control the production of red cells within the bone marrow of the body. The urinary system is made up of several organs which are as follows; kidneys, which’s function is to remove cellular waste from the blood through the use of nephrons. These nephrons contain bundles of tiny blood capillaries which are known as glomerulus. The ureters are responsible for the continual drainage of urine from the bladder and this is achieved via contractions of the ureter walls. The bladder is held in place via ligaments to the pelvis which is why the feeling of needing to bear down when the bladder is full is so dominant. The bladder tissue is isolated from urine and toxic substances by a substance that discourages the multiplication and growth of bacteria from attaching and growing on the bladder wall Generally a typical adult will be able to hold their bladder for around 5 hours, with the aid of sphincter muscles which attempt to prevent urinal leakage, though these become more unreliable over time. The urethra provides a passageway for liquid waste to be excreted from the body. If toxin should be left within the body their accumulation would lead to death. Excretion also occurs via the skin, as toxins can also be removed via the skin’s sweat glands. Homeostasis benefits from the filtration and detoxification of substances by the liver. The body is usually quite resilient at this though continual alcohol consumption can lead to disease of the liver. Osmoregulation is a particularly important process within the body that maintains balance of electrolytes and fluids within the cells. This is ideally maintained regardless of external factors that can include temperature and diet. Osmoregulation is generally a passive process which is similar to that of diffusion. Osmotic pressure has the ability to change the pressure of water within the body and therefore has a solid function in the regulation of the homeostatic nature of blood pressure. Acute glomerulonephritis is a particular type of disease that injures the part of the kidney as part of a faulty auto-immune response that mistakes the healthy body tissue of the kidney for infection, therefore attacking it causing inflammation prompting blood and protein in the urine.
If damage to the kidney continues, eventually the nephrons well die and total kidney failure will result. The acute form develops suddenly. The condition may develop after an infection in the throat or skin and symptoms commonly include facial puffiness, urine retention and bloody urine. Shortness of breath may also occur as a build up of fluid occurs around the lungs. Ordinarily acute glomerulonephritis will cease on its own, though dialysis is sometimes required for those afflicted who have a large amount of extra fluid within the body. Two further conditions are associated with this disease and those are nephritic syndrome and nephrotic syndrome. Nephrotic syndrome is characterised by the presence of proteinuria within the urine and this release of protein from the body can adversely affect osmotic processes in the body, leading towards irregular dehydration of the cells and pooling of fluids elsewhere in the body in the form of oedema, mainly noticeable within the face and
ankles.
There are two types of glomerulonephritis—acute renal failure (ARF) and chronic kidney disease (CKD). The ACF form generally develops suddenly as a result of an infection or illness, such as, group A streptococci bacteria, hepatitis, or in diseases such as lupus or HIV (Mathias, 2013). This type may require dialysis to replace renal function while it lasts, however, kidney function usually returns after the primary illness is treated. Many acute patients will not have any other complications as no permanent damage is done. Whereas CKD is found in a person that has had glomerulonephritis for months to years in some cases and may be asymptomatic until the kidney has become irreversibly damaged. ARF can evolve to become chronic if the glomeruli do not respond to
Sympathetic nervous stimulation: This compensatory mechanism is the first one. Epinephrine (adrenaline) and norepinephrine (noradrenaline) are released which causes an increase in BP and the heart to pump faster and more powerfully. They also increase cardiac output in this way it temporally helps compensate for the hearts reduced ability to pump blood. This is not good long term as it increased the amount of oxygen the myocardium needs.
occurs so the heat deep in the muscles is conserved. Since the vessels are now
When something changes in the inner environment it sends information to the receptor. The receptor sends information to the control center and then the control center sends instructions to the effector once the information is received from the control center it proceeds to either oppose or increase the stimulus. This process is designed to repeatedly work at restoring or maintaining homeostasis.
Regulation- Blood vessels help maintain a stable body temperature by controlling the blood flow to the surface of the skin (Terfera, David, and Jegtvi)
When a receptor is activated and the stimulus is taken to the hypothalamus and then relayed out to the “limbic system and neocortical areas…impulses stimulate the neuroendocrine and autonomic nervous system,” which can cause an array of issues if not careful and if the stress signal is prolonged. (3)
Nephrolithiasis, more commonly known as kidney stones, is a common renal disease characterized by crystal depositions in the kidney as a result of urinary supersaturation. There are several types of stones, such as uric acid, cystine, and struvite stones, but calcium stones are the most common.
Whilst looking at the impact that breathlessness can have on patient the author will look at the physical, psychological and social health implications and how this can affect the overall (holistic) quality of life for these patients. Often these three areas overlap and the physical implications of breathlessness can have a direct effect on the patient’s social health, financial ability to provide for themselves and others, which in turn affects the person physiological well-being or vice versa.
Homeostasis mostly works through negative feedback, this is where the effectors response lessens the effects of the original stimulu...
According to The National Kidney Foundation (2014) “Kidney Failure does not have symptoms that are found to be medical concerning which then once people find out they have Acute Renal Failure it is already in an advanced stage”. There are subjective and objective signs and symptoms for Acute Renal Failure. Subjective symptoms are Lethargy, Fatigue, restless leg syndrome, depression, shortness of breath, chest pain or pressure, confusion, intractable hiccups. Objective...
The parasympathetic nervous system does the opposite and brings the body back to normal. Sensory neurons are unipolar in shape and there are two types based on where the sensory neurons originate. Somatic sensory neurons are located in the skin skeletal muscles and joints bringing information to the CNS. It is made up of nerves that connect to skin, sensory organs, and skeletal muscles. One sensory neuron, photoreceptors in the eye, sense light. The neural impulses are then transmitted down the axons of the sensory neurons to the brain, where the brain then interprets what that input means. PNS plays a role in regulating blood pressure, thirst, and body temperature. Thermoreceptors in the skin help the body sense temperature. Motor neurons are completely different than sensory neurons, because they receive a signal from the central nervous system and tell responsive tissues what to do. Though most often associated with controlling muscle movement they also signal the glandular tissues and control secretion of various substances like gastric juices and saliva. Visceral sensory neurons give information to the CNS but not on a conscious level. Some internal organs that need regulating, but not at a conscious level are gallbladder, liver, kidney, and
From the results of the numerous tests carried out according to the patient history of frothy urine with a significant oedema over a maximum period of 5 days, the patient was diagnosed with Nephrotic Syndrome. This is condition that occurs due to leakage in the kidney filtration part leading to a large amount of protein leaking from the blood into the urine. This is mainly due to fluid retention known as oedema which is as a result of low protein level in the blood. It occurs due to abnormal functioning or a part of the kidney is affected (glomeruli). This syndrome can be caused by numerous diseases coming together to cause or form one particular disease; these causes range from minimal change disease, membranous nephropathy, focal segmental glomerulosclerosis (FSGS) and other conditions, disorders of the glomeruli. The membranous nephropathy also known as the membranous nephritis or membranous glomerulonephritis, only causes diseases in adults and very uncommon in children. Leakage occurs from this due to the thickening of the membranous in the glomeruli which is the filter of the glomeruli. Focal segmental glomerulosclerosis is a causative due to the formation of small scars (sclerosis) on some of the kidney glomeruli. Another form of cause of nephrotic is minimal change which is due to lack of virtual change detected in the glomeruli when examined under the microscope. This causes the syndrome in 9 out of a total of 10 children under the age of 5 years.
It occurs due to the overproduction of Escherichia coli and/or after kidney transplantation. The transplantation can lead to two different types diseases, chronic (long-lasting) or acute (sudden and limited). The kidney’s function are water/fluid balance, removing waste products from blood, and regulation of blood pressure via enzyme Renin. The infection is treatable via prescribed antibiotics. Lastly, pyelonephritis can be prevented by maintaining a positive healthy body. I would like to conclude that learning about pyelonephritis has made me have a different view on the importance of a fit
One of the most important changes would be an alteration in the concentration of hydrogen ions in the blood, this could be caused by a rise in blood carbon dioxide or an increase in tissue respiration in the muscles during the exercise. The respiratory centre is in its self. sensitive to raised hCo2 and responds by increasing the rate and depth. of the breath of the mind. In the aortic arch and carotid bodies there are chemoreceptors.
Lastly, blood is involved in maintaining homeostasis by negative feedback loops such as temperature regulation, blood pH, blood glucose levels, and blood pressure.