Adenomyosis: Pathology, Symptoms, and Correlations

1137 Words3 Pages

Adenomyosis Pathology
Adenomyosis is a chronic condition in which tissue from the endometrium (the innermost layer of the uterus, made up of epithelial cells) invades the myometrium (the middle layer of the uterus, made up of smooth muscle), and is associated with hypertrophy of the surrounding myometrium, dysmenorrhea, menorrhagia, and genitourinary symptoms. Adenomyosis typically affects women aged 40-50 (Naftalin, et al., 2012). There are strong correlations between adenomyosis and history of pregnancy, history of spontaneous abortion, and having a normal BMI, but no significant correlation seems to exist between adenomyosis and the mode of delivering a child or smoking (Genc, Genc, & Cingiz, 2015). There also appears to be no significant correlation between adenomyosis and race (Matalliotakis, Kourtis, & Panidis, 2005). …show more content…

Many of these estimates suffer from selection bias, as they collect their data from histopathology on the uteruses of women who have undergone a hysterectomy, therefore their applicability to the general population is unclear (Matalliotakis, Kourtis, & Panidis, 2005). One study which did not include only women who had had a hysterectomy found a prevalence of 20.9%, though this study could suffer from bias as well given that the population studied was symptomatic women who came into a gynecological clinic (Naftalin, et al., 2012). Disparities between estimates may also be a result of nonuniform criteria for defining adenomyosis (Bergholt, Eriksen, Berendt, Jacobsen, & Hertz,

More about Adenomyosis: Pathology, Symptoms, and Correlations

Open Document