Leukemia is a form of cancer that starts in the stem cells of the bone marrow that make blood cells. A bone marrow is the material that fills the center of most bones which is where blood cells are made. Leukemia is basically a blood cancer where the cells do not form properly. Leukemia is found in blood cells and since blood cells do not have chromosomes or DNA then they cannot divide or reproduce like somatic cells do. Blood cells form in the bone marrow and when too many blood cells form in the human body then Leukemia cancer is developed. There are three different types of blood cells that increase out of control and are produced in the bone marrow which are White blood cells [leukocytes], Red blood cells [erythrocytes] and Platelets. White blood cells are part of the immune system and help fight off infections. They too aid in the curing of sores, wounds and cuts. Red blood cells hold haemoglobin which carries oxygen and takes out carbon dioxide to and from the cells throughout different organs of the body. Platelets help poke holes in the blood vessels and form clots just as blood vessels are corrupted or damaged (What is Leukemia? par. 4 & 5).
When these cells in the bone marrow divide uncontrollably, they form more white blood cells than required and thus, lead to leukemia cancer. Leukemia is sometimes developed by genetic predisposition where studies researching family history look at twins who have indicated that some people have a higher risk of developing leukemia because of a single gene or multiple genes. (Silverstein 29)
Furthermore, Down syndrome is a genetic cause of Leukemia cancer. Normally, each human cell contains 23 pairs of different chromosomes. Each chromosome carries genes, which are needed for proper ...
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What is Leukemia? Leukemia is a cancer in blood forming cells that are in early stages of development. Most of the time the white blood cells, but some types of leukemia start in other types of blood cells. Blood cells are form in bone marrow. Any of these cells can turn into a leukemia cell, once this happens the cell does not mature like it should. The cell may start to produce rapidly and the mutated cells probably won’t go through apoptosis like they should. These cells build up in the bone marrow and crowd out the healthy cells. Typically, leukemia cells get into the blood stream rather quickly. From the blood stream they can spread to places like lymph nodes, spleen, liver, central nervous system or other organs where the leukemia cells can cause those other cells to function irregularly.
The emphasis on health and fitness has become paramount in our society today in an effort to prevent and combat diseases such as Cancers. Cancers are a group of over 100 diseases that affects every aspect of the human system from skin, to bones, to muscles, to blood. One of the most common blood disorders is Leukemia. As defined by the U.S. National Library of Medicine, Leukemia is a type of blood cancer that begins in the bone marrow. The bone marrow is the soft tissue in the center of the bone that is responsible for the production of blood cells. The term leukemia means white blood. The term leukocytes refer to white blood cells, which are body’s defense against infections and other foreign substances. When Leukemia occurs there is an uncontrolled increase in the number of white blood cells. When this occurs, these cancerous cells inhibit the production of healthy red blood cells, platelets, and mature white blood cells. Over time the cancerous cells can spread to the bloodstream and lymph nodes. They can also travel to the Central Nervous System and the rest of the body.
A characteristic of ALL is that it has a rapid onset and is seen usually in ages 2-8 but can affect different age groups. It is said that, a good portion of Acute Lymphoblastic Leukemia arises as a B- cell precursor. Professionals say, “ALL is associated with various alterations in the number of chromosomes and chromosomal translocations, and each specific alteration has prognostic significance” (Braun & Anderson). Possible alterations that could cause Acute Lymphoblastic Leukemia is “. . . Down syndrome, Ataxia-telangiectasia, and Neurofibromatosis type 1 (NF1)” (KidsHealth, 2014). Also, children who have had radiation or chemotherapy in the past have a higher risk factor. However, this does not mean you will have cancer or doesn’t mean you will have
Acute lymphocytic leukemia (ALL) is a form of cancer that occurs when the lymphoid stem cell is affected thereby causing abnormal white blood cells to build up in the bone marrow. This cancer rapidly produces and replaces healthy cells with immature lymphoblast. The leukemia cells moves into the bloodstream to other organs and tissues where further growth and division occurs. The proliferation of cancer cells to other area produces a variety of symptoms. ALL typically occurs in children under the age of 15, however it can happen at any age. ALL is
Leukemia is a cancer of the white blood cells. It begins in the bone marrow, the soft tissue inside the bones. Within the bone marrow is where white blood cells are created, that help fight off bacteria, viruses, and other microorganisms within the body that cause infections. The disease develops to when the white blood cells are being produced out of control. The cells that are being produced do not work properly as they should, they grow faster than a normal cell would and don’t know when to stop growing. Overtime, if not treated properly, the white blood cells will over crowd blood cells, creating a serious problem such as anemia, bleeding and infection. Leukemia cells can spread to the lymph nodes and other organs in the body causing swelling and pain.
Acute Myeloid Leukemia (AML) is the most common type of acute leukemia in adults. AML is a heterogeneous disease which results from genetic alterations in normal hematopoietic stem cells. These alterations induce differentiation arrest and/or excessive proliferation of abnormal leukemic cells or blasts [1]. Recent genomic studies have identified that recurrent somatic mutations in patients with AML blocks differentiation and/or enhance self-renewal by altered transcription factors [2,3]. The genetic or the epigenetic changes acquired by AML cells disrupt the key growth regulatory pathways and changes will make the normal cells to attain certain malignant characteristics which include inappropriate proliferation in the absence of normal growth signals, indefinite self-renewal in a manner analogous to a stem cell, escape from programmed cell death, inhibition of differentiation, aberrant cell cycle checkpoint control and genomic instability [4].
Leukemia is a cancer of the blood cells, which start in the bone marrow. The disease develops when the blood cells produced in the bone marrow grow out of control. The cause for leukemia is unknown.
It’s very strange how the appearance of such an illness can appear but they have been able to come up with a few theories to how. One of the theories they have come up with is that there may have been some type of exposure to radiation when the mother was pregnant with the child or even at any point of their early life. It has been showed that too much exposure to ionizing radiation can damage DNA which can later on lead to leukemia. A second theory is that the child inherited a gene mutation which can cause the cells to grown uncontrolled which in the end turns into cancer. It can develop as early as when the child is in the womb. Children that are born with conditions such as Down syndrome have a higher chance of getting leukemia than a child without that condition.
Kanwar, V.S. (2013, Sep 16). Diseases & Conditions - Medscape Reference. Pediatric Acute Lymphoblastic Leukemia. Retrieved January 13, 2014, from http://emedicine.medscape.com/article/990113-overview#a0156
Childhood leukemia is a fast-growing cancer, most common in teens and children. It is cancer of the white blood cells. The affected cells for in the patient's bone marrow and very quickly travel through the bloodstream, attacking any healthy cells they encounter on the way. There are many things that may cause this cancer.. Some causes can be low immune system, and unhealthy environmental surroundings such as smoking. There are also some argued-about causes that are a bit on the controversial side, such as living near a nuclear power plant, or how old the patient’s mother was when they were born. The most common cause currently known is heredity.
ALL, the most prevalent form of childhood acute leukemia, is a blood cancer. Acute Lymphocytic Leukemia occurs when bone marrow cells develop errors in its DNA (Mayo Clinic). Consequently, cell proliferation occurs without dividing; therefore, resulting in abnormal blood cell production. The bone marrow produces immature cells that develop into leukemic white blood cells called lymphoblasts (Mayo Clinic). Incapable of functioning properly, abnormal cells
The disease is known by the uncontrolled growth of blood cells, usually white blood cells in the bone marrow (“Leukemia Information”). The leukemia cells overcrowd and replace normal blood and marrow cells (“Leukemia Information”). Leukemia is likely to occur when when some blood cells have mutations in their DNA. There could be other changes in cells that could contribute to the forming of Leukemia (“Leukemia”). According to Leukemia Causes - Mayo Clinic, Certain abnormalities cause the cell to grow and divide more rapidly and to continue living when normal cells would die. Over time, these abnormal cells can crowd out healthy blood cells in the bone marrow, leading to fewer healthy white blood cells, red blood cells and platelets, causing the signs and symptoms of leukemia (“Leukemia”). Leukemia is classified based on its speed of progression and the type of cells involved
Leukemia forms in an easy way. Leukemia is thought to form when the blood cells start to mutate in humans DNA. There might be other changes that may not have been classified yet. Certain abnormalities cause the cell to grow and divide rapidly and continue living when the other normal cells die. Over time, these abnormal cells can crowd out healthy blood cells in the bone marrow, leading to less healthy white blood cells, red blood cells and platelets. ( Mayo Clinic )
Acute lymphocytic leukemia, or ALL, is a type of cancer that starts in the bone marrow where early blood cells are made. It is also called acute lymphoblastic leukemia. (American Cancer Society, 2016). Leukemia is cancer of the blood and the blood forming tissues. It is characterized by overproduction of lymphocytes. Acute leukemias involve lymphocytes that grow rapidly, but abnormally (Leukemia, 2016). According to American Cancer Society (2016), “The term ‘acute’ means that the leukemia can progress quickly, and if not treated, then it could be fatal within a few months. Lymphocytic means it develops from early forms of lymphocytes, a type of white blood cells.”
Leukemia is a disease in which the bone marrow and other cells are not functioning properly which produce the numbers abnormal cells. Scientist do not know the exact cause of leukemia. Some scientist say that leukemia can be cause by a DNA mutated by some blood cells. There are 4 types of leukemia, leukemia is a cancer that’s start in the blood forming cells of the bone marrow. When one of these cells changes and become a leukemia cell (cancer.org). Red blood cells and white blood cells are completely different. They both are needed for the body to function properly. The red blood carry oxygen while the white blood cells do not (wisgeek.org). If there are too much white blood cells in the body and less red blood cells in the body can led to