The microbe Naegleria fowleri, commonly called the brain-eating-amoeba, was first identified from a fatal case of primary amebic meningoencephalitis (PAM) in Australia in 1961. In 1965, three further cases of fatal PAM were found, from which clinical and laboratory investigations pointed to a relation with acute bacterial meningitis among the cases of an unknown etiology. According to Fowler & Carter (1965), when post-death examinations of the bodies were performed researchers found that “microscopically