Technology in the last few decades has impacted our understanding of biological entities greatly, the genome project being a prime example. The progress that biology sees follows closely with the development of new technology. It is very important to understand and visualise the composition and structures of biological materials or samples in order to extend and correlate this to the principles of life. Microscopy is a by far the most used and the most relevant technique in this regard. However the
determine bioavailability of phenolic acids and possible metabolites in blood. Some of these methods include electron impact mass spectrometer (EI-MS), atmospheric pressure chemical ionization mass spectrometer (APCI-MS), electro-spray ionization mass spectrometer (ESI-MS), and matrix-assisted laser desorption/ionization mass spectrometer, (S Bertuglia, et al) as well as the more conventional HPLC after identification.
Introduction Although some infections are unique enough to be identified clinically, usually microbiologic laboratory methods are needed to identify the etiologic agent and diagnose microbial infection (Washington, J.A., 1996). Although we have made significant progress in our ability to diagnose and treat infectious diseases, they still remain a strong challenge to human survival, for example the disease Tuberculosis caused by a microbial infection with Mycobacterium tuberculosis accounted for one