(1) St. John’s wort Hypericum perforatum is a botanical name of St John's wort. It belongs to a family of Clusiaceae or Hypericacacae. Hypericaceae or St. John's wort family or Clusiaceae is one and same thing. It is a flowering plant species of the genus Hypericum and a medicinal herb that is sold globally and good treatment for major depressive disorder {1, 2}.It has been demonstrated by various studies which conclude that st. john's wort is generally as useful against depressions as other modern
St. John's Wort and Depression What is St. John's Wort? St. John's Wort scientifically known as Hypericum Perforatum, an herbal remedy generally used to treat depression, is making a rise throughout Europe and the United States. St. John's Wort is a perennial plant that produces abundant yellow flowers and grows naturally throughout much of the world, including specifically in northern California, southern Oregon, and Colorado. It usually flowers on “sunlight hills and forest edges” during
Pharmacodynamics St. John’s Wort, also known as Hypericum perforatum, contains multiple substances that produce medicinal effects within the body. The two most active components are hyperforin and hypericin, which produce therapeutic benefits (Russo et al., 2014). Hyperforin and hypericin have been found to impact neurotransmitter activity, specifically by decreasing neurotransmitter reuptake, resulting in mood stabilization and analgesia (Russo et al., 2014). In addition to its neurologic effects
Depression is the leading cause of disability globally. 18 million adults in US are affected by it, twice as many women as men. It is ranked right after high blood pressure in terms of chronic medical condition. Even though many people are affected by it, millions more cases are not diagnosed because people are reluctant to seek help, fearing the stigma which is attached to mental illness or they simply do not realize they are ill. The symptoms can range from mild to severe, feeling hopelessness