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Gene therapy position paper
Gene therapy disagreement essay
Gene therapy disagreement essay
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Imagine that one day your son or daughter get diagnosed with a terminal disease and the doctor tells you that you can try to use Gene Therapy to save them except it is an experiment so it might be risky. Even though this might not happen because it is a new technique and isn't funded for hospital use you can still have knowledge about it if you read this paper.
Gene Therapy is a process where they take healthy DNA or Stem Cells and use them on damaged or infected versions to make them healthy again. You might not know much about it because it doesn't have as much funds as many other things but it helps people get better in less time. I believe with Gene Therapy we can cure many of the illnesses in the world.
Treatments that include Gene Therapy are limited but here are a few. A tool called the "Skin Gun" uses healthy skin stem cells and when you spray them on burned cells it heals them in a matter of 3-4 days. In normal burned skin treatment they "grow" skin which takes a week or two. Scientists take DNA out of your body or another body and change them outside the body and then put...
Gene therapy is the application of the technique where the defect-causing "bad" genes are replaced by correct "good" genes. The idea of gene therapy is to treat the disease by correcting the "bad" DNA (Deoxyribonucleic acid) rather than the current me thod of providing drugs, or proteins not produced by the defective gene. Gene therapy addresses the problem first hand by directly working with the genetic information causing the disease. From the book Shaping Genes, Dr. Darryl Macer says "It is like f ixing a hole in the bucket, rather than trying to mop up the leaking water." There are two kinds of gene therapy, somatic cell gene therapy and germline gene therapy.
There have been four somewhat recent successful gene therapy treatments. The four deal with correcting hemophilia, bone marrow transplants, skin cancer, and vessel growth. In the success with the bone marrow transplants, French researchers collected bone marrow cells from patients, used gene therapy to correct the bone marrow, and then returned the bone marrow to the patient. This was 80% successful as reports 16 months after the transplants showed. Squamous cell carcinoma, skin cancer of the head and neck, was treated using gene therapy as well. The fourth trial was where DNA was used to carry a substance that stimulates blood vessel growth to damaged heart tissue and in this trial there was much success noted.
It was in the 1980’s that scientist began looking at alternative ways of treatments, one is gene therapy. Scientist would insert human genes into a bacteria cell. Then the bacteria cell would transcribe and translate the information into a protein. Once that is done the scientist would then introduce the protein into human cells. Gene therapy can be simply viewed as inserting bits of foreign DNA into a patient’s tissue in hope...
A molecular biologist by the name of James Watson once said, “we used to think that the fate was in our stars, but now we know that, in large measure, our fate is in our genes.” The Oxford Dictionary defines gene therapy as the transplantation of normal genes into cells in place of missing or defective ones in order to correct genetic disorders. Gene therapy has the ability to prevent, treat, and even cure diseases by replacing a faulty gene with a stable, healthy one (American Medical Association). Aldous Huxley’s, Brave New World, relates to gene therapy because they program each embryo with how they should live. This essay will first talk about why gene therapy is done and how it works.
Have you ever seen a movie or read a book where they can tell what your child will look like or if they have a disease or birth defect. Or have you ever wondered how the world would be shaped if we could have clones or even erase genetic diseases. All of these things are theoretically possible with stem cell research. If we are able to reach this point what would we have to sacrifice in the process. To understand humanity would we have to sacrifice the values that truly make us human? What would the fail rate be if we are able to genetically enhance the human body?
Over 40 years ago, two men by the names of James Watson and Francis Crick discovered deoxyribonucleic acid, or DNA. DNA is hereditary material in humans and almost all other organisms (What is DNA?). From this finding, gene therapy evolved. Today, researchers are able to isolate certain specific genes, repair them, and use them to help cure diseases such as cystic fibrosis and hemophilia. However, as great as this sounds, there are numerous ethical and scientific issues that will arise because of religion and safety.
USA Today 127.2644 (1999): 28. " In Vivo Somatic Gene Therapy." Brown University. Web. 18 Nov. 2011.
Gene therapy gives people who suffer from genetic diseases a chance to lead a normal life. Dangerous diseases, such as AIDS, SCID, Thalassemia and ADA can be cured successfully. In September 5, 2006, two people with advanced melanoma received Gene therapy and they got recovery soon. This is a breakthrough in cancer gene therapy. Gene therapy uses patients own cells to cure diseases, and, therefore, no rejection to their bodies. Furthermore, patients could get permanent cure from gene therapy without recurrence.
In the past 40 years, scientists have developed and applied genetic engineering to alter the genetic make-up of organisms by manipulating their DNA. Scientists can use restriction enzymes to slice up a piece of DNA from an organism with the characteristics they want and spliced (joint) to a DNA from another organism. DNA that contains pieces from different species is called recombinant DNA, and it now has different genetic material from its original. When this DNA inserted back into the organism, it changes the organism’s trait. This technique is known as gene-splicing (Farndon 19).
"What's the worst that can happen to me? I die, and it's for the babies," said Jessie Gelsinger as he left for the hospital to receive gene therapy treatment. (Stolberg) People risk their lives everyday in the name of science. One such science that people have recently been drawn to is gene therapy. Although, gene therapy may be new and exciting and it may be helping to find cures to diseases we only dreamed of curing, we have to remember it is dangerous. It needs to be done with much supervision. Every new step we take in the advancement of gene therapy should be thought over because the consequences could reach farther then we ever believed they could. There are so many dangers of the techniques used that can lead to consequences as serious as death. The government imposes many guidelines, and it needs to stay that way. The biggest dangers, however, may be in what is to come.
"The aim is to decrease the fear of a brave new world and to encourage people to be more proactive about their health. It [Gene therapy] will help humans become better physically and even mentally and extend human life. It is the future” (Hulbert). Dr. Hulbert, a genetic engineer, couldn’t be anymore right; more time, money, and research needs to be put into gene therapy and genetic engineering, since it can cure certain illness and diseases that are incurable with modern medicine, has fewer side-effects than conventional drugs or surgery, and allows humans to be stronger physically and mentally at birth. Gene therapy or genetic engineering is the development and application of scientific methods, procedures, and technologies that permit direct manipulation of genetic material in order to alter the hereditary traits of a cell, organism, or population (NIH). It essentially means that we can change DNA to make an organism better. Genetic engineering is used with animals and plants every day; for example with genetic...
Could you imagine being able to create new organs, tissues, muscles, and even food? With embryonic stem cell technology, believe it or not, these things are possible. Stem cells are the body's raw materials. Specifically, they are cells from which all other cells with specialized functions are generated. Under the right conditions in the body or in a laboratory, stem cells can divide to form more cells called daughter cells. These daughter cells either become new stem cells or turn into specialized cells with a more specific function, such as blood cells, brain cells, muscle cells or bone cells. The possibilities are almost endless. The debate and main issue with this technology is that the actual stem cells come from embryos. Embryos are an unborn or unhatched offspring in the process of development. Although there is controversy surrounding these cells, embryonic stem cells should continue to be researched and used, because they have so much potential.
Gene therapy is a provisional technique that is the insertion of normal genes into the cells where there is a missing or miscoded gene to fix a genetic disorder. In the 1960s and early 1970s,
Genes are made of DNA – the code of life (Gene Therapy- The Great Debate!). The changes in genes may cause serious problems, which we called genetic disorder. In theory, the only method to cure genetic disorders is gene therapy, which basically means the replacement of genes in order to correct the loss or change in people’s DNA. Although gene therapy gives patients with genetic disorders a permanent cure, it is controversial because it has safety and efficacy problems, and raises ethical issues.
In the end, gene therapy in humans needs to come a long way before it will be widely accepted, but there is great potential in the technology and it needs to be pursued. Bibliography Anderson, W. F. (1992). The Species of the World. Human Gene Therapy -. Science, 256 (5058), 808-813.