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Recommended: Psoriasis lesion
Psoriasis is an autoimmune disease that affects 125 million people world wide according to the World Psoriasis Day consortium. What causes psoriasis is unknown, but many doctors and researches believe that genetics and environmental factors trigger a hyperactive reaction of the immune system. This response then causes skin cells to multiply and mature rapidly, therefore causing the skin cells to buildup on top of each other and then eventually become red, scaly, itchy, and thick patches on skin. Even though this disease is the most common auto-immune disease in the world, there is no cure for it. Psoriasis can lead to other problems depending on the severity of the disease, however, this chronic disease has several treatment options in order to prevent further damage. Although there is no cure for psoriasis, understanding how it begins, recognizing the symptoms, and learning about treatment options can enhance the quality of life for a person diagnosed with psoriasis.
Even though it is unknown on what triggers psoriasis, doctors and researchers do know where it begins. What triggers psoriasis remains unknown, but it is known that an hyperactive auto-immune response is what leads to psoriasis. In a person without psoriasis, their skin takes about 3 weeks to a month for their skin to be renewed and replaced with new skin. However, in a person diagnosed with psoriasis, their skin cells are rapidly reproducing within days which causes the skin cells to build on top of each other. These skin cells reproduce rapidly because the immune system activates T cells (white blood cells) that begin to attack? healthy skin cells by releasing cytokines.
Cytokines are proteins that begin to signal an abnormal inflammatory response to skin cells ...
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...of the skin and slows down the process of skin growth. Phototherapy is often used without the usage of other medicine, but if the psoriasis is very severe, than it can work well with other treatments. The most common risk factor of using this method is skin cancer and skin damage around the edges of the unaffected area.
Lastly, topical treatments are medicine that are applied to the skin. These creams, gels, oils, foams and lotions are used as an anti-inflammatory agent. These have ranges of potency from super potent to least potent or 1-7. For example, corticosteroid, the most common prescribed topical, is a steroid that affects the growth and inflammation of the epidermis. However, this is often used for mild to moderate cases only since side effects of using topical treatments can result in changing of the skin, dilated blood vessels,and irritation of the skin.
The immunologic events that are happening at the local level during Carlton's acute inflammatory response would be:
The second layer of the skin is called the dermis and is also known as the middle layer. The dermis is what holds the body together. The dermis has layers to it as well as the epidermis. There are two layers to the dermis, the papillary layer and the reticular layer. The cells of the dermis are fibroblast, macrophages, mast cells, and scattered white blood cells (wbc’s). the dermis is richly supplied with nerve fibers and BV;s. dermal BV’s is also a part of the integumentary system, dermal BV,s have converging and diverging vessels that ar...
The immune system is made up of a network of cells, tissues, and organs that work together to protect the body, and it defends the body from “foreign invaders.” Immunity can be divided in two three different defenses, and these are defined as first, second and third lines of defense. The first line of defense for the immune system is the primary defense against pathogens entering the body from the surface in order to prevent the start of disease and infection. Some examples of the first line of defense is the skin, protecting the external boundaries of the body, and the mucous membranes, protecting the internal boundaries of the body. Although the skin and mucous membranes work on the internal and external boundaries, they both release chemicals
“Immune Response: MedlinePlus Medical Encyclopedia.” National Library of Medicine - National Institutes of Health. Web. 18 Dec. 2011. .
Rosacea is a common skin disorder of the facial skin that affects well over 16 million Americans without them knowing the condition is present. It appears as red discoloration or bumps on the surface of the skin. Over time, the redness becomes brighter and more persistent and blood vessels begin to appear on the skin. The cause of this condition is unknown, but could be caused by hereditary or environmental factors. A number of these same factors can trigger the rosacea and send blood rushing into the surface of the skin. These factors can include alcohol, extreme temperatures, sunlight/wind, emotions, exercise, and certain cosmetic items. All of these factors combined could cause a flare up of the disorder at any given time.
... certain adrenal cortical steroids are powerful inhibitors of inflammation, toxic side effects limit their usefulness. Similarly, drugs that inhibit proliferation of cells in the inflammatory masses have potentially severe side effects. Drugs that inhibit undesirable inflammation may also inhibit desired inflammatory responses.
It is still unknown what the cause of Rheumatoid Arthritis is but there are some theories that have not been proven. The oldest theory states that viruses and bacteria are the cause of Rheumatoid Arthritis. Now with all the research being done, scientists believe that Rheumatoid Arthritis is hereditary. Specific genes have been found to make people more likely to get Rheumatoid Arthritis. Some scientists also think that some environmental factors and infections might cause the immune system to attack. Contributing factors are smoking and being exposed to silica metal. So although the exact causes are unknown, the result is that the immune system is ready to make the joins and tissues inflamed by activating immune cells.
DO you know what Lupus is? Or do you know anyone with Lupus? You’ll be surprised to know that over 1.5 million people are affected by Lupus and of every 170 people 9 out of 10 of them are women. Even though that Lupus can be dated back to the Greek physician Hippocrates many people are still blind to this disease. Lupus can affect you, your love ones and the people around you because, like many other autoimmune diseases Lupus does not discriminate. I’m surprised that not many people know what Lupus is, especially when someone is diagnosed with lupus every 30 minutes. When I was diagnosed I was relieved to finally know I was not going crazy and there was actually something wrong, but at the same time scared out of my mind because there is no cure. (Rupavate, 2014)
UV radiation causes significant damage to human skin, in the form of sunburns, aging, skin cancer, and nonmelanoma tumors. Human skin damage is primarily a result of tanning. The
Skin Cancer is caused by hereditary factors, overexposure to the sun, and weak immune systems. (“Skin Cancer” infotrac.com) One reason people tend to get skin cancer is when someone in your family has passed their genes down to you, known as hereditary. Normally hereditary is one of the causes in the development of melanoma. For all types of skin cancers, overexposure of the skin to UV radiation in sunlight is the most frequently blamed source of skin cancer. “Research suggests that sunburns received early in one’s childhood can lead to skin cancer later in life” (“Skin Cancer” infotrac.com). For example, when someone gets sunburned, you usually don’t know till ten to twenty years after and that’s why people don’t get skin cancer till they reach their twenties.
Psoriasis is a chronic skin disorder, easily identified by its symptoms of white, scaly skin and red lesions, though not so easily cured or understood. In psoriasis, skin cells mature faster than the body can shed them, causing a buildup. Although there are many theories as to what the cause of such a disease might be – genetics, stress, or other triggers – no one is quite sure why the disease occurs, or what could be a possible way to fully cure it. In this essay we will explore the symptoms, types, and effects of this condition, and also some of the known treatments.
While sitting around your house, watching television, you notice that you have been scratching your arm and in between your fingers for a little while. After taking a closer look you notice something that you assume is a rash and just ignore it. The next day however you notice that the rash has spread and that you think you see burrows in your skin. Then it hits you, the weekend that you spent away on vacation in that not so expensive hotel to save a couple of dollars has now cost you more money in the long run. You must go see your doctor to be treated for scabies!
Because of of the neutrophils, dendritic cells, macrophages, other cells involved in the disease, we are led to a debate. Is psoriasis caused by the skin’s T cells, or just the skin? The first hypothesis was that psoriasis is a disorder of the epidermis due
Atopic dermatitis causes inflammation of the skin, lesions of the skin, and chronic infections. This can happen on multiple body sites and critical body areas and this can result in very serious limitations. For example, it could interfere with the motions of my joints, limit the use
Chickenpox is contagious one to two days before an infected person gets the rash until all of the chicken pox blisters have become scabs. It typically takes 10 to 21 days to develop chickenpox after being exposed to the virus. For most, once you contract chicken pox, you are immune for life. In some, however, you can get chicken pox more than once. This is not common.