XYY Syndrome is a rare genetic disorder which affects males due to an extra Y chromosome. Healthy males have 46 chromosomes including one X and one Y chromosome. Men with XYY syndrome have 47 chromosomes, two of which are Y chromosomes. It is not known why the extra Y chromosome occurs. The disorder is present at birth and is estimated to occur in one out of every one thousand live births.
In very rare instances, the syndrome has been passed from father to son, but in most cases heredity cannot be established.
The characteristics of XYY syndrome are often very subtle and do not indicate and serious chromosomal disorder. Therefore, males with this condition are frequently undiagnosed or misdiagnosed. The primary symptoms include tall or very tall height which becomes evident at the age of five or six, and severe cystic acne during adolescence.
Lower than average intelligence and/or behavioral problems, such as an explosive temper, aggressive or defiant actions, or sometimes antisocial behavior are other symptoms. Some individuals with this disorder may also have language difficulties or psychosexual problems. XYY Syndrome is often undiagnosed until tests for other medical reasons are performed. Other than being unusually tall and/or having behavioral problems, in many cases, these boys or men appear normal. Physical characteristics of XYY Syndrome may include an exceptionally long head with a slightly protrusive forehead, long hands and feet, long ears, mild indentation of the breastbone, and/or large teeth. Poor chest and shoulder muscle development is also common. Even though males with this syndrome are large, they tend to be weak and uncoordinated. Some may have a fine intentional tremor, such as shaking hands when the try to drink a glass of water. Occasionally, a bony formation across the joints in the two bones of the forearm resulting in the stiffening of the affected joints may occur. Other occasional symptoms are undescended testicles, a small penis, or an opening located on the underside of the penis.
For a long time it was thought that XYY Syndrome individuals
18. a) Explain the process of nondisjunction can result in an individual with Klinefelter syndrome. Create a diagram showing the disjunction occurring in the mother to help explain your answer. Individuals with Klinefelter syndrome have XXY chromosomes, and can occur when during the prophase of meiosis I, in females there is nondisjunction of X chromosomes. This results in a male with trisomy. One egg can have no X chromosomes and the other could receive both X chromosomes.
Tics are the most common symptom of Tourette syndrome. A tic is an involuntary, repetitive movement of muscles usually in the face, neck, shoulders, trunk and hands (Diane, 2011, p.662). Symptoms of Tourette syndrome is often first noticed during childhood, between ages 7 and 10. Most children with Tourette syndrome also have other medical problems such as ADHD and OCD Tourette syndrome exhibit multiple behavioral symptoms including ADHD and OCD, which, like Tourette syndrome, are clinically diagnosed without testing (Chiu, 2013, p.406). According to the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision, motor and vocal tics are classified as simple or complex (Diane, 2011, p.663). Simple motor tics include eye blinking, neck jerking, shoulder shrugging, head banging, head turning, tongue protrusion, nail biting, hair pulling, and facial grimacing (Diane, 2011, p.663). Some examples of complex motor tics are facial gestures, grooming behaviors, hitting or biting oneself, jumping, hopping, touching, squatting, retracing steps, smelling an object, and imitating the movements of ...
Genetic disorders can be caused by many of the 46 chromosomes in human cells. This specific disorder is linked to a mutation in the long arm of the X, or 23rd chromosome. The mutation is recessive, meaning a normal X chromosome can hide it. Females have two X chromosomes allowing them to hide the mutated recessive one, making them a carrier of the gene, while males only have one X chromosome, meaning that they are unable to hide the mutation and they become effected by the disease. Therefore if a male carries the gene, he is affected because he has no way of dominating the recessive gene, but if a female carries it, she is only a carrier and has a 50/50 chance of passing it on to her baby. This may seem like a high probability however, only one in every fifty thousand male births will have this immunodeficiency disease.
People who have been diagnosed with this lifelong disease have either started to see the early signs and symptoms or have yet to recognize them. The negative impact that fatigue, loss of muscle strength and in-coordination has on the patients with Parkinson’s disease can be improved with a well-balanced exercise regimen. The three most common physical symptoms the patient will experience are tremors, rigidity, and bradykinesia. “Tremors while at rest are the most common initial symptom and are present in around 70 percent of cases at disease onset. It often presents as a pill rolli...
Have you or anyone in your family experienced unusual tremors in your head or any part
Here are some interesting facts about Turner’s. This syndrome affects 60,000 women in the United States, and is seen 1 to 2500 babies born and about 800 cases are diagnosed each year. The single X chromosome comes from the mother in 75% to 80% of cases. A woman with Turner’s Syndrome, who is untreated, averages around four feet eight inches in height. A female, XX, who is missing one of the X chromosomes, can survive. However, a male cannot survive without the X chromosome. Butterflies are seen as a symbol of hope for girls who have Turner’s Syndrome.
OTHER NAMES Depending on the doctor, Turner's Syndrome may be diagnosed with one of the following alternative names: 45 - X Syndrome, Bonnevie-Ulrich Syndrome, Chromosome X, Monosomy X, Morgagni- Turner-Albright Syndrome, Ovarian Dwarfism, Turner Type, among others. SYNDROME CHARACTERISTICS A reduced growth in height is the commonest visible characteristic of the syndrome, (the average adult height is 4 feet 8 inches) and may be the only sign before puberty. Their body proportions are normal.
Normally those who are affected with Jacob Syndrome look normal in physical appearance besides the fact that they are taller th...
The most common way of getting Angelman syndrome is through chromosome deletion. This is responsible for about 68% of all cases o...
The fact that early signs of Parkinsonism can easily be overlooked as normal aging, further complicates diagnosis. Therefore, primary care physicians of the middle-aged and elderly population must be extremely sensitive to patients’ outward appearance and changes in movement ability. Most signs and symptoms of Parkinson disease correspond to one of three motor deficiencies: bradykinesia, akinesia, tremor, and rigidity. The first two qualities are usually present before tremor, but often attributed to aging by the patient and even the physician, and thus the disease is rarely diagnosed until tremor becomes evident much later. An average of 80% of the nigrostriatal neurons may have already degenerated by the time Parkinsonism is diagnosed, which complicates treatment (Fitzgerald, 130).
Parkinson disease (PD), also referred to as Parkinson’s disease and paralysis agitans, is a progressive neurodegenerative disease that is the third most common neurologic disorder of older adults. It is a debilitating disease affecting motor ability and is characterized by four cardinal symptoms: tremor rigidity, bradykinesia or kinesis (slow movement/no movement), and postural instability. Most people have primary, or idiopathic, disease. A few patients have secondary parkinsonian symptoms from conditions such as brain tumors and certain anti-psychotic drugs.
Cyclothymic disorder, also known as cyclothymia, is a relatively mild form of bipolar II disorder characterized by mood swings that may appear to be almost within the normal range of emotions. These mood swings range from mild depression, or dysthymia, to mania of low intensity, or hypomania. It is possible for cyclothymia to go undiagnosed, and for individuals with the disorder to be unaware that they have a treatable disease. Individuals with cyclothymia may experience episodes of low-level depression, known as dysthymia; periods of intense energy, creativity, and/or irritability, known as hypomania; or they may alternate between both mood states. Like other bipolar disorders, cyclothymia is a chronic illness characterized by mood swings that can occur as often as every day and last for several days, weeks, months, or as long as two years. Individuals with this disorder are never free of symptoms of either hypomania or mild depression for more than two months at a time (Encyclopedia of Mental Disorders).
Many people around the world today suffer from Parkinson’s disease and other movement disorders. A movement disorder is a disorder impairing the speed, fluency, quality, and ease of movement. There are many types of movement disorders such as impaired fluency and speed of movement (dyskinesia), excessive movements (hyperkinesia), and slurred movements (hypokinesia). Some types of movement disorders are ataxia, a lack of coordination, Huntington's disease, multiple system atrophies, myoclonus, brief, rapid outbursts of movement, progressive supranuclear palsy, restless legs syndrome, reflex sympathetic dystrophy, tics, Tourette's syndrome, tremor, Wilson disease, dystonia, which causes involuntary body movement, and Parkinson's disease. Parkinson’s disease, Tourette’s syndrome, and tics are one of the most widely known of these disorders, known to impair people of movements and rob them of their lives.
...e, mouth, face, or whole body; involuntary chewing, sucking, and lip smacking; and jerky movements of the arms, legs, or entire body” (Comer, 2011, p. 379).