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Essay opioid epidemic women
Opioid crisis research paper
Thesis statement and outline for The Opioid Crisis in America
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The Pharmaceutical company, Purdue Pharma, is manufacturing and falsely marketing highly addictive prescription drug, OxyContin, in the United States. According to the CDC (Center for Disease control), opioid deaths have gone up 400% since 1999. Purdue Pharma, is deceiving the public about the safety of opioids. They are engaging in marketing campaigns and claiming that these harmful painkillers can be prescribed without a significant risk of addiction. When in fact, people do become addicted to painkillers, and nearly 90 of them lose their life each day due to opioid overdose. OxyContin was first introduced in 1995, and it was Purdue Pharma’s first major painkiller. According to FDA, OxyContin was supposed to be taken every 8 hours, but Purdue
Pharma marketed it as “smooth and sustained pain control all day and all night when it was taken every 12 hours”, when in fact it does not control pain in 12 hours and it is resulting in withdrawals and constants craving for the drug.1 The company was aggressively pressing doctors to start prescribing the drug to the patients, “When patients started complaining that the painkillers don’t last for 12 hours, the company told the doctors to prescribe stronger doses, which can lead to overdose and death.”2 Prescription opioids and heroin use in United States cost around 80 billion annually. These actions are impacting US taxpayers who are, among other things, paying for public health and law enforcement costs. ISSUE: According to Section 502 of the Federal Food, Drug and Cosmetic Act (FFDCA) that contains provisions on misbranding Purdue Pharma broke these three laws: 1. Its labeling is false or misleading in any particular. 2. Its label does not bear adequate directions for use including warnings against use in certain pathological conditions or by children where its use may be dangerous in health or against unsafe dosage, or methods, or duration of administration or application. 3. It is dangerous to health when used in the dosage or manner or with the frequency or duration prescribed, recommended or suggested in the labeling.3
Case 1: In this case. As a certified public accountant, Erickson oversaw and initiated an arbitrary adjustment to increase cash and decrease accounts receivable. Also, Erickson signed Form 10-K with full knowledge that the financial statements include therein incorporated entries misstating revenues. As we can see from this case, Erickson’s behavior not only violate the Business and Professions Code, Division 3, Chapter 1, § 5100(g) and (i), but also against the ethical theories.
?). Drug use and abuse has become a widespread issue within the United States. One of its most troubling aspects being the abuse of pharmaceutical and prescription drugs, painkillers raising the most concern. Drugs such as Oxycontin, Ambien, and Xanax are being prescribed by doctors and given to the public and then being misused, causing more harm than good. ADD SOURCE THAT EXPLAINS THE MANIFESTATION OF THIS. Barbara Ehrenreich, an American author and sociologist explores this very problem in her book, Nickel and Dimed. When talking about a worker’s use of medication, Ehrenreich claims that, “Unfortunately, the commercial tells us, we workers can exert the same kind of authority over our painkillers that our bosses exert over us. If Tylenol doesn’t want to work for more than four hours, you just fire its ass and switch to Aleve”(25). In other words, Ehrenreich is stating how the media is pushing drugs onto the working class and through the use of personification she illustrates how workers identify themselves with the medications they are taking. Employees will opt for the most efficient medication in order to be efficient themselves, which reduces them to a less than human kind of being for their employer’s benefit. If any of the employees fail to meet the expectations set for them, a new recruit from the company’s “pool of cheap labor” can easily replace them. Pharmaceutical and prescription drug abuse is becoming a growing concern amongst low wageworkers because of their variety, easy access, and social acceptance.
The documentary states that over 27,000 deaths a year are due to overdose from heroin and other opioids. According to the Center for Disease Control and Prevention in 2015 prescription pain relievers account for 20,101 overdose deaths, and 12,990 overdose deaths are related to heroin (Rudd et al., 2010-2015). The documentary’s investigation gives the history of how the heroin epidemic started, with a great focus on the hospice movement. We are presented with the idea that once someone is addicted to painkillers, the difficulty in obtaining the drug over a long period of time becomes too expensive and too difficult. This often leads people to use heroin. This idea is true as a 2014 survey found that 94% of respondents who were being treated for opioid addiction said they chose to use heroin because prescription opioids were “more expensive and harder to obtain (Cicero et al., 2014).” Four in five heroin users actually started out using prescription painkillers (Johns, 2013). This correlation between heroin and prescription painkiller use supports the idea presented in the documentary that “prescription opiates are heroin prep school.”
Almost one hundred years ago, prescription drugs like morphine were available at almost any general store. Women carried bottles of very addictive potent opiate based pain killers in their purse. Many individuals like Edgar Allen Poe died from such addictions. Since that time through various federal, state and local laws, drugs like morphine are now prescription drugs; however, this has not stopped the addiction to opiate based pain killers. Today’s society combats an ever increasing number of very deadly addictive drugs from designer drugs to narcotics to the less potent but equally destructive alcohol and marijuana. With all of these new and old drugs going in and out of vogue with addicts, it appears that the increase of misuse and abuse is founded greater in the prescription opiate based painkillers.
In 1906, the Pure Food and Drug Act, that was years in the making was finally passed under President Roosevelt. This law reflected a sea change in medicine-- an unprecedented wave of regulations. No longer could drug companies have a secret formula and hide potentially toxic substances such as heroin under their patent. The law required drug companies to specify the ingredients of medications on the label. It also regulated the purity and dosage of substances. Not by mere coincidence was the law passed only about five years after Bayer, a German based drug company began selling the morphine derivative, heroin. Thought to be a safe, non-habit forming alternative to morphine, heroin quickly became the “cure-all drug” that was used to treat anything from coughs to restlessness. Yet, just as quickly as it became a household staple, many began to question the innocence of the substance. While the 1906 law had inherent weaknesses, it signaled the beginning of the end for “cure-all” drugs, such as opiate-filled “soothing syrups” that were used for infants. By tracing and evaluating various reports by doctors and investigative journalists on the medical use of heroin, it is clear that the desire for this legislative measure developed from an offshoot in the medical community-- a transformation that took doctors out from behind the curtain, and brought the public into a new era of awareness.
Direct-to-consumer prescription drug ads are dangerous and can have serious effects on the health of the general public. In the article “Pros & Cons Arguments: ‘Should prescription drugs be advertised directly to consumers?’”, the pros and cons of the advertising of prescription drugs are compared. The negative aspects of these ads outweigh that of the positives. DTC prescription drug ads misinform patients, promote over-usage, and pressure medical providers. The counter side argues that these ads inform patients, create a positive impact on patient compliance with medication, and cause patients to confront their doctors.
Background: Merck & Co. is an American pharmaceutical company and one of the largest pharmaceutical companies in the world. In 1971 the United States approved the use of an MMR vaccine made by Merck, containing the Jeryl Lynn strain of mumps vaccine. In 1978 Merck introduced the MMR II, using a different strain of the rubella vaccine. In 1997 the FDA required Merck to conduct effectiveness testing of MMRII. Initially it was over 95%; to continue the license; Merck had to convince the FDA that the effectiveness stayed at a similar rate over the years.
By the year 2000 opioid medicine containing oxycodone etc., are being abused and misused and more than doubled in 10 years’ time.
Opioid’s chemical composition consist of many highly addictive substances which cause the human body to become quickly tolerant. Many opioid users become addictive to the substance because the doctors have been over prescribing. “In the United States, there were 14,800 annual prescribed opioid (PO) deaths in 2008” with the US having less restrictions (Fischer, Benedikt, et al 178). The United States have implemented more regulations so that “high levels of PO-related harms been associated with highly potent oxycodone formulas” will decrease (Fischer, Benedikt, et al 178). With the regulations, it does not change the fact that opioids are is destructive. The regulations assistance by lessening the probability of patients becoming addictive to opioid. There are numerous generations that are effected and harmed by the detrimental effects of opioids on opioid-dependent patients.
On the typical day, over 90 people will die at the hand of opioid abuse in America alone (National). In fact, as of 2014, nearly 2 million Americans were dependent and abusing opioids. The Opioid Crisis has affected America and its citizens in various ways, including health policy, health care, and the life in populous areas. Due to the mass dependence and mortality, the crisis has become an issue that must be resolved in all aspects.
An Analysis of GlaxoSmithKline The business that I have done research into is GlaxoSmithKline. This company is a globalised research-based pharmaceutical public limited company. Its ownership structure has changed a great deal since the original company was first established in 1715. Originally a pharmacy, the company has expanded, merged with and taken over other companies over the decades.
Threat of new entrants is relatively high. Companies forming alliances are potential rivals. Even if earlier such company was not considered to be a threat, after merging with some research and development company or forming alliance with another pharmaceutical company it would become a rival to Eli Lilly. The threat is however weakened by significant research and development costs necessary to successfully enter the business. Eli Lilly’s focus on a relatively narrow market of sedatives and antidepressants weakens the threat of new entrants, but other products that form lesser part of company’s sales such as insulin and others are exposed to high threat of new entrants. The need of obtaining certificates and licenses also weakens the threat of new entrants. Discussed above leads to the conclusion that threat of new entrants is medium.
The rate of death due to prescription drug abuse in the U.S. has escalated 313 percent over the past decade. According to the Congressional Quarterly Transcription’s article "Rep. Joe Pitt Holds a Hearing on Prescription Drug Abuse," opioid prescription drugs were involved in 16,650 overdose-caused deaths in 2010, accounting for more deaths than from overdoses of heroin and cocaine. Prescribed drugs or painkillers sometimes "condemn a patient to lifelong addiction," according to Dr. Tom Frieden, director of the U.S. Centers for Disease Control and Prevention. This problem not only affects the lives of those who overdose but it affects the communities as well due to the convenience of being able to find these items in drug stores and such. Not to mention the fact that the doctors who prescribe these opioids often tend to misuse them as well. Abusing these prescribed drugs can “destroy dreams and abort great destinies," and end the possibility of the abuser to have a positive impact in the community.
In recent years’ health reform has been a driving force in the United States political system. If you watch the news you will undoughtabley hear how citizens, the government, or the economy is or might be effected by some sort of change in medical regulation. One of these hot topic issues is the cost of prescription drugs. Every major drug market besides the United States regulates the price of drugs in some way (Abbott and Vernon). By the United states not doing so many believes it opens consumers up to be exploited by large pharmaceuticals companies. Other believe regulating drug prices limits investment, innovation, and competition in the pharmaceutical industry. In many ways both views are correct yet the later may have more long term lasting
With the increased cost of manufacturing, pharmaceutical companies have been divesting in their smaller or less profit making operations and focus on large segments. Many Pharmaceutical companies sold their manufacturing sites to contract manufacturing organizations. The dynamics of interfacing with contract manufacturing organization added intricacy in pharmaceutical supply chain network of pharmaceutical companies.