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Smallpox history research paper
Smallpox history research paper
Cause and effect of smallpox
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Imagine it, you’re a Native American in 1763. Men come on your land handing out blankets ,after a day of using the blanket you begin to get a fever. Two days later you begin to receive a rash, bumps filled with pus all across your body, sound familiar?You didn’t know then but we know now that this was smallpox,but what is smallpox? How did it start? Is the virus still active? What is its history? No matter what your question is (In regarding to smallpox) it will be answered today in my essay.
Smallpox is a disease caused by the complicated variola virus.The result of smallpox is a high fever and pus filled blisters on the skin. Smallpox is spread through saliva , coughs/sneezes, sharing of needles,and skin to skin contact. Smallpox has been around since or before 3000 years ago with the earliest case being in 1157 with pharaoh Ramses V. ,his mummified body indicates the scars of pockmarks, but there is no actual way to know when or how smallpox originated.
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At the height of the United States smallpox epidemic in the late 1700’s and early 1800’s , English doctor Edward Jenner noticed that milkmaids that had gotten cowpox (another skin disease caused by contact from he infected cows udder and a person) were immune to smallpox and showed no symptoms of the disease after being in contact with the infected, making him think cowpox somehow prevents someone from getting smallpox.
This idea came from Edwards milkmaid Sarah Nelmes and James Phipps, a 9 year-old son of Edwards gardener. Edward injected the cowpox virus into James. James was now infected with cowpox (cowpox Ian not deadly ) After this he injected the smallpox virus into James. James showed no signs of the smallpox disease, this made the worlds first vaccine , the smallpox
vaccine. The last outbreak of smallpox in America was in 1949. The last person to die from the disease was Janet Parker ,a British medical photographer that came in contact with the infected, this was in 1977. Smallpox in itself has killed over 3 million people.Due to the fact that the variola virus has been eradicated across the world, they no longer vaccinate for it. On September 11, 2001 the world went into shock, it was the day at which the worst terrorist attack in American history took place. What does this have to do with smallpox? Well after the bombing of the World Trade Center a concern was that there would be a bio terrorist attack with smallpox.(much like how there was the mailing of anthrax to political officials and became infected) There is two places on earth where the variola virus is still kept,one being Russia , the other being a CDC in . The reasoning for this is Incase there ever is another outbreak they will have the variola virus on hand to make vaccines. This was debatable though because if the virus ever ended up it the wrong hands it could potentially cause another viral outbreak . Now I’ve answered all the basic history and science questions but there is one question that still remains, could there be another smallpox epidemic, and that’s a question I do not have the answer to.
“Future nations will know by history only that the loathsome smallpox has existed and by you extirpated”. This quote comes from Thomas Jefferson to Edward Jenner, he founder of the smallpox vaccine. It would only be 100 years later that Jefferson would see his dream fulfilled, but not without struggle. In House on Fire, author William H. Foege shares his first hand view of the lengths that society needed to go through to rid the world of the disease that had plagued it for so long. The story of the fight against smallpox extends long before our efforts for global eradication and is a representation of how society deals with widespread disease. House on
In closing, the variola virus affected a great amount in that era including, military strategy, trade, and native populations. Elizabeth A. Fenn’s book Pox Americana: The Great Smallpox Epidemic of 1775-82 sheds light on a significant aspect of that era that had not been given proper credence beforehand. She also illuminated the effect of smallpox when it came to race and social status. With regard to race, smallpox decimated much of the non European populations partly because of their lack of an innate immunity to that virus and Europeans lack of regard for those of a different race. Fenn’s argument on social status showed how the poorer strata’s of society suffered more severely from the variola virus because of their lack of finances to get inoculated; thus, the poor often suffered a worse strain of the virus which often lead to death.
Blackbird's book, like many similar autoethnographic texts, is a combination of autobiography, history, ethnography, and polemic. He opens with a conventional reference to inaccuracy in current histories. In the course of correcting the record he relates the story, preserved by elders of his nation, of a smallpox epidemic during the height of the French and Indian War, about 1757. Blackbird's story is unique because of the unusual disease vector.
You woke up a week ago feeling odd. You were not sure what was wrong, but your body was full of aches, you felt hot to the touch, and you kept vomiting. Your mother told you to lay down and rest, hoping it was just a cold. After a few days, you began to feel better, well enough that you wanted to return to the river to watch the trade ships come in. Now, unfortunately, your symptoms have come back with a vengeance – your fever is back along with intense abdominal pain, your mouth is bleeding without being wounded, and every time you vomit, it appears black in color. Also, when you look in the mirror, your skin has changed from the sun-kissed color you have always been to a dull yellow hue. The doctor comes in to examine you; he makes many “tsk tsk” noises and hurries out of the room with a cloth over his face. The doctor mumbles to your mother that he believes you have Yellow Jack and there is nothing more he can do, you are going to die. Your mother weeps uncontrollably yet you cannot react because another horrendous pain in your head has doubled you over. Soon, as you stop shaking and begin to relax, the sounds of the doctor and your mother become white noise and your surroundings begin to dull until you prove the doctor right; another person fell victim to the infectious Yellow Fever virus.
The first discovery was made in 1952, in the developing field of virology. Virology is the study of viruses and how they behave. To develop the vaccines for the viruses, researchers infected the HeLa cells with many types of infections, such as measles, mumps, and the infamous poliomyelitis virus, also known as Polio. According to the Centers for Disease Control and Prevention (CDC), whose mission is to save lives and protect people’s health security, Polio is a "crippling and potentially deadly infectious disease caused by a virus that spreads from person to person invading the brain and spinal cord and causing paralysis" (Freeman). Jonas Salk, who was a virologist at the National Foundation for Infantile Paralysis (NFIP), used inactivated viruses (virus particles grown in culture and then killed by a form of heat) to create a polio vaccine. Salk drew blood from about two million children, which the NFIP checked for immunization.Through the collection of many HeLa cells and trial and error, the polio vaccine wa...
Edward Jenner, “the father of immunology”, was born on May 17, 1749. He was one of nine siblings and he was treated for smallpox for a very long period of his childhood. I predict that his treatment to small pox as an infant encouraged his work into creating the vaccine for smallpox itself. It is said that his work “saved more lives than the work of any other human”. He found the similarities of cowpox and smallpox, and then analyzed his experiments to conclude that previous cowpox patients had immunization to smallpox.
... risk of developing the disease. It was observed that those who had been infected with the clinically similar but less severe cowpox disease by milking cows were also immune to smallpox. This observation led Edward Jenner to his first ever vaccination technique. He inserted the cowpox virus obtained from the scabs of a woman into a boy, and then when the boy was inoculated some time later, he proved immune to smallpox (Fenner). It is impossible to contract smallpox from this inoculation of the less virulent related virus and allowed individuals a way to protect themselves without risk. Later, the smallpox vaccination was adapted by using a different live virus, the vaccinia virus which is more similar to variola than cowpox and therefore provides better cross-immunity. As the practice of vaccination gained popularity, it had a significant impact on life expectancy.
The perspective the author gives to this book is a unique. Smallpox according to most histories does not play the role of a major character, but a minor part. In my opinion smallpox was a major factor during the Revolutionary War, and Feen focuses on several key areas which allows us to see just how bad this epidemic was and the grip it had not only on the soldiers, but the colonist as well.
In order to understand the history of smallpox one first has to understand how diseases like it evolve. Much like other species, diseases that survive in the long run are the microbes that most effectively reproduce and are able to find suitable places to live. For a microbe to effectively reproduce, it must "be defined mathematically as the number of new infected per each original patient." This number will largely depend on how long each victim is able to spread the virus to other victims (Diamond, 198).
From 166 A.D. to 180 A.D., The Antonine Plague spread around Europe devastating many countries. This epidemic killed thousands per day and is also known as the modern-day name Smallpox. It is known as one of deadliest plagues around the world.
By preserving the virus, Boylston personally inoculated 247 people in 1721 and 1722 to prevent transmission. However, from there only six people died, and Boylston was the first American surgeon to inoculate his patients personally. The author portrays the background data Boylston used to examine the inoculation practice on different age and gender of persons to treat his patients from previous experiments. The inoculation method provided higher level of immunity in preventing smallpox infection. The prevention of smallpox is through inducing antibodies through vaccines which last longer for a person taking it.
During one of his earlier apprenticeships, Jenner noticed milkmaids with a disease called cowpox. Cowpox is a close relative to smallpox and is only mild in humans. Pustules appear on the hands and a basic cold is also brought on. At Jenner’s young age he was able to link these two viruses together and come up with a theory for immunization. In 1796, while still attending medical school, Jenner decided to test this theory between smallpox and cowpox. He used a dairymaid, who was a patient of his named Sarah Nelms, who had contracted cowpox and had ripe pustules on her hands. Jenner realized this was his opportunity to test someone who had not contracted smallpox yet. He picked an eight-year old boy named James Phipps to use as his test subject. He scraped open a spot of James' arm and rubbed in a dissected piece of Sarah Nelms pustule into the open wound. A couple days later James became ill with cowpox but was well again within a week. This test proved that cowpox could be spread between humans as well as cows. Jenner's next test would be if the cowpox virus gave James immunity against smallpox. On July 1st of 1796, Edward Jenner obtained an infected smallpox pustule and scratched the virus filled pus into James' arm. This technique of placing a virus into a patient is called variolation. James Phipps did not develop smallpox within the
Smallpox is a disease from the variola virus. Smallpox has caused an estimated number of 300 million deaths in the 1900s alone. Smallpox is said to have been around since the ancient Egyptian times. The disease was eradicated in the late 20th century and two samples are still kept, one in U.S.A and one in Russia. Smallpox creates bumps and blisters all over the body and has been one of the most fatal epidemics the world has seen.
Illness has been a major part of humankind’s lives almost since the beginning of time. Throughout history, illnesses caused fatal epidemics that caused deaths between young and old, and brought fear upon all for the absence of a cure. Having an illness throughout most of history was considered an inevitable death sentence, as the majority of causes of death (Offit). Vaccinations have been experimented in China and Turkey in the 15th century, with methods such as inhaling or rubbing grounded up smallpox scabs against open cuts (Clem). Then in 1700s, the first form of modern vaccination was invented by Edward Jenner with the cowpox virus acting against smallpox, giving immunity against it (Offit).