Vaccine Research Paper

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Vaccines have been around for hundreds of years starting in 1796 when Edward Jenner created the first smallpox vaccine. Jenner, an English country doctor noticed cowpox, which were blisters forming on the female cow utters. Jenner then took fluid from the cow blister and scratched it into an eight-year-old boy. A single blister came up were the boy had been scratched but it quickly recovered. After this experiment, Jenner injected the boy with smallpox matter. No disease arose, the vaccine was a success. Doctors all around Europe soon began to proceed in Jenner’s method. Seven different vaccines came from the single experimental smallpox vaccine. Now the questions were on the horizon. Should everyone be getting vaccinations? Where’s the safety limit? How can they be improved? These questions needed answers, and with a couple hundred years later with all the technology, we would have them(ncbi.nlm.nih.gov).

Since the smallpox vaccine was invented, there have been over a hundred other vaccines created. Every vaccine created goes into one of the seven types of vaccines. One type being live or attenuated, which means the vaccine contains a live virus that has been weakened or altered so it doesn’t cause illness. Attenuated vaccines are good “teachers” for the body since they’re the closest thing to a natural infection. An example of an attenuated vaccine would be the vaccination for the measles, mumps, yellow fever or the chicken pox. Attenuated vaccines can be made in several ways. Most common method involves taking the virus and putting it through series of chick embryos. When the virus passes through the embryos it loses the ability to reproduce in human cells. The only downside to the attenuated vaccine is that it doesn’t work o...

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...us or bacterium used as the carrier. Recombinant vector vaccines are still being experimented on today, just like the DNA vaccinations. The only difference between recombinant vector vaccines and DNA vaccines is the fact recombinant vector vaccines use an attenuated virus or bacterium to introduce microbial DNA to the body’s cells. Scientists created this vaccine by observing nature, and how nature passes viruses along. Scientists noticed that viruses in nature latch on to the cells they want to inject, this caused scientists to figure out how to take parts of an attenuated virus and add genetic matter from other microbes into them. I know this sounds confusing, but it’s quite simple. Just think of it as poisoning the virus. Recombinant vector vaccines are very close to mimicking a natural infection, which causes the immune system to energize and start up sooner.

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