Introduction: Gas in 1968 described Acute Posterior Multifocal Placoid Pigment Epitheliopathy (APMPPE) as being a condition that caused acute and rapid loss of central vision due to multiple pale lesions at the level of Retinal pigment epithelium (RPE) in the posterior pole. (1) It is a self-limiting condition which recovers spontaneously over a three weeks period leaving residual pigment epithelial alterations.(2) The typical features in acute phase include cream colored placoid lesions at the level of RPE, early hypofluorescence and late hyperfluorescence of the lesions on Fundus fluorescein angiography (FFA).(2) It is usually followed by a viral flu like prodrome in 1/3 of the patients. Neurological manifestations of APMPPE include Headaches being commonest while others are paraesthesias, vertigo, psychosis and more severe complications, Cerebrospinal fluid pleocytosis stroke and cerebral vasculitis.(3, 4) Association of APMPPE with systemic Vasculitis in the patients with positive perinuclear antineutrophil cytoplasmic antibody has been reported.(5, 6) Other systemic inflammatory diseases suggesting an underlying immune mediated or an inflammatory mechanism include erythema nodosum,(7-9) juvenile rheumatoid arthritis,(10) thyroiditis,(11, 12) nephritis,(5, 6, 13) ulcerative colitis(14) and Adenoviral infections(15) . Many granulomatous diseases have documented associations with APMPPE, including Wegener’s granulomatosis,(16-18) Pulmonary tuberculosis(19) and Sarcoidosis. The widespread involvement of Retinal Pigment Epithelium (RPE), flat (placoid) nature of the lesions and absence of overlying serous retinal detachment and minimal choroidal involvement lead Gass to conclude RPE was primary focus of inflammation.(1) ... ... middle of paper ... ...th recurrent stroke. Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society. 2009;29(2):111-8. Epub 2009/06/06. 30. Bures-Jelstrup A, Adan A, Casaroli-Marano R. [Acute posterior multifocal placoid pigment epitheliopathy. Study of 16 cases]. Archivos de la Sociedad Espanola de Oftalmologia. 2007;82(5):291-7. Epub 2007/05/23. Epiteliopatia pigmentaria placoide posterior multifocal aguda. Estudio de 16 casos. 31. Celis Sanchez J, Gonzalez Del Valle F, Alonso Martinez I, Romero Royo C, Lopez Ferrando N, Zarco Tejada JM. [Bilateral serous retinal detachments in acute posterior multifocal placoid pigmentous epitheliopathy]. Archivos de la Sociedad Espanola de Oftalmologia. 2001;76(11):679-82. Epub 2001/11/21. Desprendimientos retinianos serosos bilaterales en la epiteliopatia pigmentaria placoide multifocal posterior aguda.
Mr. Fix-it is a 59 year old man with a history of alcohol abuse and diabetic hypertension. Mr. Fix-it has been currently experiencing symptoms such as: rambling speech, poor short-term memory, weakness on the left side of his body, neglects both visual and auditory stimuli to his left side, difficulty with rapid visual scanning, difficulty with complex visual, perceptual and constructional tasks, unable to recall nonverbal materials, and mild articulatory problems. The diagnosis for Mr. Fix-it’s problem is most likely a right-hemisphere stroke. A right-hemisphere stroke is occurs when a blood clot blocks a vessel in the brain, or when there is a torn vessel bleeding into the brain. “A right-hemisphere stroke is common in adults who have diabetes and who are over the age of 55”, similar to Mr. Fix-it (Kluwer, 2012). In addition, Mr. Fix-it has a history of alcohol abuse in which it could have also increased his chances of experiencing a right-hemisphere stroke.
In the end, regardless of the scientific methods that could be used to treat different diseases and more specifically retinal degeneration, many studies should be conducted determine the potential clinical application of photobiomodulation with NIR for treatment of different injuries and disorders.
Saxena, Rohit, Diguijay Singh, and Praveen Vashist. “Glaucoma: An Emerging Peril.” Indian Journal of Community Medicine 38.3 (2013): 135-7: Proquest. Web. 7 Jan 2014.
•The forty five year old patient is diagnosed with the progressive cirrhosis inflaming the liver along with the parenchymal cells. The plain symptoms is manifested primarily because of the augmentation of edema internally in the lower abdomen.
1. What is the difference between a. and a. Introduction The main aim of this report is to present and analyse the disease called Cerebrovascular Accident, popularly known as stroke. This disease affects the cerebrovascular system, which is a part of the cardiovascular system.
15. Sepici-Dincel, Aylin. "Choroidal Neovascular Membrane in Age-Related Macular Degeneration is Associated with Increased Interleukin-6." International Journal of Gerontology: 101-104. Web. 1 May 2014.
Stroke occurs when the blood supply to the brain is blocked or condensed. Blood works to transport oxygen and other beneficial substances to the body’s cells and organs, as well as the brain. There are two main types of strokes that are known as Ischemic strokes and Hemorrhagic strokes. When the blood vessels that provides for the brain becomes congested, is it referred to as ischemic stroke, the most common stroke within adults. Blood clots, a cluster of blood that sticks together, are the cause of Ischemic strokes. Ischemic strokes also takes place when arteries become backed up with plague, leaving less blood to flow. Plague is cholesterol, calcium and fibrous and connective tissue that sticks to the walls of blood vessels. Ischemic strokes eternally damage the brain and cause a person's body to no longer function habitually.Some risk factors that may increase stroke are high cholesterol, diabetes, high blood pressure, and obesity. Some stroke factors are also due to old age or having a family that has a history of strokes. Men are more likely to have a stroke but the most st...
These lesions have unique characteristics; they have top hypermineralised layer with different thickness that has bacterial inclusions that are sitting on denatured collagen fibril...
Many signs include a "white pupil," also known as leukocoria. Retinoblastoma can occur in either one or two eyes (Paul T. Finger, Pg. 1). This abnormal white pupillary reflex is sometimes referred to as a cat's eye reflex. Another sign of retinoblastoma is a crossed eye (Ambramson, Ch3). Leukocoria doesn't always end up as being retinoblastoma, it can even result in: congenital cataract, Toxocara canis, Coat's disease, and persistent hypertrophic primary vitreous (PHPV) (Finger, Pg.2). Retinoblastoma occurs when there's a mutation or deletion of the q14 band of chromosome 13 (Finger, Pg. 1). Symptoms can be painful if not treated quickly. Some include a red, painful eye, swelling of the surrounding eye, poor vision, dilated pupil, even extra fingers or toes, and retardation (Ambramson, Ch3).
Macular degeneration in general can affect many people in minor or drastic ways. People who experience this form often complain of vision loss when they are in dim light, especially when they are reading. The "dry" type is often characterized by a more gradual loss of vision compared to the "wet" type. Signs of this disease include an increase in drusen, which is an accumulation of a yellow-white substance, in the underside of the macular retina. A loss of cells can be seen in the macula. The macula is our sensitive sight region, where intricate detail can be seen. Thus, vision in this area is helpful and necessary to drive, read, focus on small details, and recognize familiar faces. The macula is located in the back of the eye known as the retina. The macula is only about 5 mm in diameter, and includes the fovea, which gives us our detailed central vision. If a person suffers from the "dry" form in one eye they will be more likely to develop it in the other eye as well.
Stroke is a serious medical condition that affects people of all ages specifically older adults. People suffer from a stroke when there is decreased blood flow to the brain. Blood supply decreases due to a blockage or a rupture of a blood vessel which then leads to brain tissues dying. The two types of stroke are ischemic stroke and hemorrhagic stroke. An ischemic stroke is caused by a blood clot blocking the artery that brings oxygenated blood to the brain. On the other hand, a hemorrhagic stroke is when an artery in the brain leaks or ruptures (“About Stroke,” 2013). According to the Centers for Disease Control and Prevention (CDC), “Stroke is the fourth leading cause of death in the United States and is a major cause of adult disability” (“About Stroke,” 2013). Stroke causes a number of disabilities and also leads to decreased mobility in over half of the victims that are 65 and older. The CDC lists several risk factors of stroke such as heredity, age, gender and ethnicity as well as medical conditions such as high blood pressure, high cholesterol, diabetes and excessive weight gain that in...
-Characterized by the elongation and hyperkeratosis of the filiform papillae, resulting in this hairlike appearance. The elongated papillae usually exhibit brown, yellow, or black pigmentation. Most patients are asymptomatic, but occasionally patients complain of irritation, gagging, or an altered taste. Patients are usually heavy smokers with poor oral hygiene and some have vitamin deficiencies, GI problems, or radiation therapy. Cures range from just brushing the tongue to corticosteroid therapy.
And the retina. These are all on the wall of the eyeball, the fibrous tunic consist of
I realized it was a stroke,” –Fred, a stroke survivor. Some of the most common symptoms indicating that a stroke is occurring include sudden numbness or loss of movement in the limbs on one side of your body or face, sudden vision changes, sudden trouble speaking, sudden confusion, a very intense headache, or sudden balance issues. Stroke is simply acquired when the blood supply to the brain is suspended, but to get to the roots of what causes it, a stroke is triggered by the slowly forming plaque buildup over time. The plaque is made up of calcium, fat, cholesterol, cellular waste, and fibrin, a material involved in blood clotting. The plaque existing in an artery can grow big enough to block the supply of blood to the brain, resulting in a stroke. A stroke can also be caused by high blood pressure breaking a blood vessel in the brain causing internal bleeding. Although there is no cure, as damage the brain is usually irreversible if not cared for quickly; there are different treatments available for both types of stroke. For an ischemic stroke, a tissue called plasminogen activator can be injected into an artery to break up