Azithromycin is Azithromycin is a macrolide antibiotic active in vitro to treat major pathogens that cause infections of the respiratory tract, other tissues and according to Wilson, Hannon, and Shields, they are: “bacterial infections, acute bacterial sinusitis, otitis media, pneumonia, tonsillitis, or pharyngitis.”(2014) It is manufactured under the trade name such as Azasite, Zithromax, and Zmax. Azithromycin acts by getting in to the 50S ribosomal subunit of susceptible microorganisms and blocked their regular protein making process.
Azithromycin is contraindicated with patient who has an allergy reaction with its components. Beside that, it is also dangerous for patient has history of jaundice and liver disease cause by using this drug in the past. On the other hand, to be safe before taking the drug, patients need to tell their primary MD if they have the following conditions: liver disease, kidney disease, myasthenia gravis, or a heart rhythm disorder. Azithromycin should not be used with digoxin, cyclosporine, phenytoin, dihydroergotamine, and ergotamine because it may increase the toxicity level of those drugs. Food may also reduce its ability to absorb by half of its full potential. Azithromycin needs to be used with caution when dealing with older adult with liver or kidney impairment, gastrointestinal disease, lactation, and children under 6 months old.
On the other hand, according to one study, the ability of macrolide antibiotics class to contraindicate with some of other drugs has been widely known. According to Westphal’s study in 2000: “Macrolides can induce their own hepatic biotransformation into nitrosoalkanes, which later form an inactive CYP3A4-iron-metabolite complexes to prevent the formation of the C...
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...ould reconstitute to the final concentration of 100mg/ml first, then solution must be further dilute into 1mg/ml or 2mg/ml by adding 5ml of the original solution to 500ml or 250ml of normal saline or other compatible solution. It should be administer over 3 hours for 1mg/ml or over 1 hour for 2mg/ml for intermittent administration, and for oral form, it should be one hour before or two hours after meal. Beside that, a key thing to educate patient and family are to minimize direct sunlight during treatment, can only take magnesium or aluminum 2 hours before or after taking this drugs. On the other hand, when giving azithromycin to patient, the nurse should monitor for loose stool or diarrhea, monitor closely for PT and INR with concurrent use of warfarin, and especially report any sign and symptom of hypersensitivity because it can be serious even though it is rare.
4. Although iron is a critical nutrient, and can be beneficial to your body, too much iron can allow infections to develop quicker. When Dr. Weinberg tested tetracycline by adding a bit of it to Petri dishes with bacteria and various other nutrients, Dr. Weinberg concluded that the dish that contained iron, even though the antibiotic was present, fostered an extreme amount of development of bacteria. The control variable in this experiment would be just the ...
Meanwhile, a study made by Palmer found that inhaled antibiotics used as adjunct to systemic antibiotic therapy has proven to improve the clinical outcome of patients with MDR VAP (6). The study also showed a direct relationship between antibiotic resistance with the se of systematic antibiotics. Aerosolized antibiotic used in this study that are proven to be effective are: amikacin, colistin, ceftazidime, gentamicin, tobramycin, sisomycin, and yancomycin.
...ucts are in the wrong conformation, the antibiotic will not work affectively in a patient’s system. This is especially useful when there are a set number of starting products, and one wishes to proceed down a chemical pathway in a certain number of steps. This reaction is also utilized as an “environmentally benign approach [to] solvation” (Morrison, et al., 2001) as well as in the production of “complex natural products” in chemical synthesis (Akiyama, et al., 2009). Robinson Annulation is a useful reaction, but not the simplest, so other types of enantioselective synthesis reactions have also been thought up, including “the Lewis acid catalyzed reaction of” regioselective compounds (Huffman, et al., 1985). Lastly, there is a Robinson Annulation Reaction involved in the synthesis of morphine, one of medicine’s basic “pain killer” medications (synarchive.com).
Overall, I retain three goals for this clinical day: Safely and efficently administer medication, enhance my nursing/CNA skills, and determine how to implement infection control into a health care setting. This week reflects my assigned time to administer medication in a health care setting for the first time, with a resident who retains nearly twenty medications. I except this experience will be a great learning experience, but it will also subsist slightly stressful. With the assistance of my FOR, my goal is to administer all of my resident 's medications without complications. To ensure that medication safety, I will perform the six medication rights and three checks prior to administration. Along with medication administration, a goal
Cephalexin is an oral antibiotic that treats different bacterial infections found in the body. For a UTI, cephalexin is an effective antibiotic. It interferes with the bacteria 's ability to build a cell wall by killing and preventing the growth of bacterial cells. It stops the bacteria from forming a cell wall around each cell which is used to protect the bacteria from the outside environment, and helps keep the contents inside the cell safe. Without a cell wall, the bacteria would be incapable of survival (Medicinecabinet, 2016). Cephalexin is not only effective but also very safe due to the amount of dosage and its
Antibiotics basically refer to chemical substances that can inhibit and destroy the growth of microorganisms (Gottileb,1976; Katz and Demain,1977). Antibiotic term was first used in 1942 by Selman Waksman to describe any substance produced by a microorganism which interfere with the growth of other microorganism (SA Waksman, 1947). Each antibiotic is produced by a relatively limited number of species and is inherited from specific set of genes. These are the products of secondary metabolism which can be produced commercially by microbial fermentation after active growth has declined. These compounds are generally synthesized in stationary phase especially idiophase (unbalanced growth phase) so these are sometimes called as idiolites(walker, 1974). Their formation is highly influenced not only by the growth conditions but also by the composition of the culture medium.
With anything in life there are risks with taking dietary supplements. If a person takes to many dietary supplements it could become seriously and even lead to death. Taking dietary supplement can conflict with other medications a person is taking. Over-the-counter or prescribed medications can conflict with dietary supplements and person might not even know it. You should always consult your doctor or pharmacist before adding a dietary supplement. They will ensure you that there is no danger between the
The dosage of the drug should be used according to the carton instructions. A 10 gram over dose in adults, 140 mg for kids, can cause permanent liver damage. Also if you had just taken some other drugs , The acetaminophen may become more toxic since the drugs are catabolized in the liver. To protect yourself from injury, you should take 1 gram of vitamin C and Cysteine -a bodily antioxidant.
...blood and increase the absorption and concentration of digoxin in the blood. This may reduce the effectiveness of ketoconazole or increase digoxin toxicity. Through unknown mechanisms, omeprazole may increase blood levels of saquinavir and reduce blood levels of nelfinavir and atazanavir, drugs that are used for treating patients with infection caused by the human immunodeficiency virus (HIV). Omeprazole can be contraindicated in patient with hepatic impairment thus doctors are advised not to prescribe more than 20mg daily of omeprazole for such patients. [1] [3] [4]
Furosemide is available in tablets, sublingual tablets, oral suspension, and intravenously. (2) The recommended schedule dose for adults for an initial dose is 20 to 80mg. (3) The same dose as well as higher doses may be administered 6 to 8 hours following the previous dose if needed. (2) When titrating doses it may be raised by 20 to 40mg but not within 6 to 8 hours after the initial dose, and this may continue until the desi...
In the last decade, the number of prescriptions for antibiotics has increases. Even though, antibiotics are helpful, an excess amount of antibiotics can be dangerous. Quite often antibiotics are wrongly prescribed to cure viruses when they are meant to target bacteria. Antibiotics are a type of medicine that is prone to kill microorganisms, or bacteria. By examining the PBS documentary Hunting the Nightmare Bacteria and the article “U.S. government taps GlaxoSmithKline for New Antibiotics” by Ben Hirschler as well as a few other articles can help depict the problem that is of doctors prescribing antibiotics wrongly or excessively, which can led to becoming harmful to the body.
Precision of a patient’s intravenous medication is essential; it must be safe from. contamination, toxicity, and side effects. Most people believe these medications are compounded or mixed by a trained and licensed individual. However, this is inaccurate because the pharmacy technician actually compounds a large percentage of a patient’s medications. Compounding involves a technician’s math skills, aseptic technique, and professional ethics.... ...
In the year 1980 GlaxoWellcome entered the pharmaceutical industry with their product Zantac, an H2 receptor antagonist. Zantac achieved greater success over competing medications such as Tagamet for various reasons. Zantac seemed an attractive alternative to Tagamet as it was available as a single daily dose that could be taken before going to sleep. Tagamet had to be administered three times a day before meals. Zantac was also slightly more effective than Tagamet in reducing symptoms and suppressing the secretion of stomach acid. The healing speed and healing efficacy were also marginally higher in comparison to Tagamet. (Collen, 1984) The official labelling on Zantacs packaging stated fewer side effects than SmithKline’s Tagamet and Zantac could also be used by children and pregnant woman. Tagamets labelling indicated otherwise. This led many to believe that Glaxowellcomes Zantac was a safer, healthier option.
The discovery of antibiotics is attributed to Alexander Fleming who discovered the first antibiotic to be commercially used (Penicillin) in approximately 1928. An antibiotic, also known as an antimicrobial, is a medication that is taken in order to either destroy or slow the growth rate of bacteria. Antibiotics are integral to the success of many medical practises, such as; surgical procedures, organ transplants, the treatment of cancer and the treatment of the critically ill. (Ramanan Laxminarayan, 2013)
-Educate patient that this medication may reduce the absorption of antacids, calcium, and iron. Take 4 hours apart from antacids, calcium and iron supplements.