Wait a second!
More handpicked essays just for you.
More handpicked essays just for you.
About Tissue engineering
Don’t take our word for it - see why 10 million students trust us with their essay needs.
Recommended: About Tissue engineering
Tissue engineering is a field which involves biology, medicine, and engineering. It aims at restoring, maintaining and enhancing tissue and organ function by implanting natural, synthetic or semi-synthetic tissue and bioartificial organs that are fully functional from the beginning, or that grow into the required functionality (Nature Publishing Group., 2014). It is emerging as a potential alternative or complimentary solution for organ failure.
Basic Tissue Engineering Principles (Castells-Sala, et al., 2013).
A real-life example of its application in the human body is in wound repair. The main focus of tissue engineering in this application is in artificial skin to treat burns but it can also be used in various other dermal diseases. An example of this is the Advanced Tissue Sciences Dermagraft, which is a 3 dimensional human neonatal dermal fibroblast culture that has been grown on a biodegradable scaffold and has been cryopreserved (Nature Publishing Group., 2014). The main function of a scaffold is to direct cell behaviour such as migration, proliferation, differentiation and maintenance of phenotype (Amoabediny, Salehi-Nik, & Heli, 2011). The use of this Dermagraft is in the treatment of foot ulcers that have developed as a side effect of long – term diabetes. According to clinical trials, significant healing occurred with this material especially when the Dermagraft cells were alive and fully functional.
The manner in which the Dermagraft works is that it is placed on the ulcer and the mesh material gradually seeps into the skin where the human cells grow into place and replace the damaged skin. The living cells present in the Dermagraft produce many of the same proteins and growth factors found in healthy skin whi...
... middle of paper ...
...ssue Engineering/Regenerative Medicine. Retrieved April 5, 2014, from Tissue Engineering Pages: http://www.tissue-engineering.net/index.php?seite=whatiste
WebMD. (2012, December 14). WebMD. Retrieved April 27, 2014, from Central Venous Catheters: http://www.webmd.com/pain-management/tc/central-venous-catheters-topic-overview
Wendt, D., Timmins, N., Malda, J., Janssen, F., Ratcliffe, A., Vunjak-Novakovic, G., et al. (2008). Chapter 16: Bioreactors for tissue engineering. In C. van Blitterswijk, P. Thomsen, A. Lindahl, J. Hubbel, D. F. Williams, R. Cancedda, et al., Tissue Engineering (pp. 484-488). Elsevier Inc.
Yannas, I. V. (2000, August 15). pnas.org. Retrieved April 27, 2014, from PNAS: www.pnas.org
Zielinski, B., & Lysaght, M. (2007). Chapter 28: Immunoisolation. In R. Lanza, R. Langer, & J. Vacanti, Principles of Tissue Engineering (p. 399). Elsevier Inc.
When microdermabrasion removes the outer layer of skin the body then goes into a healing mode that promotes the making of new healthier cells. Microdermabrasion is like when one sustains an injury to his skin and the body sends treatment molecules to heal the damage. Mariane Fernandes conducted an experiment with the aim to evaluate the effects of microdermabrasion on skin rejuvenation. Fernandes stated in her article “Effects of microdermabrasion on skin rejuvenation” in the Journal of Cosmetic and Laser Therapy that “Microdermabrasion treatment promoted skin rejuvenation through an increase in skin thickness due to an increase in epidermal thickness and collagen organization” (Fernandes 26). Acne weakens and thins the skin epidermal layers, causing acne scars. Microdermabrasion heals the weak, thin, and fragile skin, which makes the skin smooth and more resistant to other damaging conditions. Doctor Bruce M. Freedman an aesthetic plastic surgeon and assistant professor of plastic surgery at Georgetown University also analyzed the dermatological changes associated with microdermabrasion in “Clinical and histologic changes determine optimal treatment regimens for microdermabrasion” in the Journal of Dermatological Treatment. Freedman’s experiment also yielded results of an increase of epidermal thickness
The second layer of the skin is called the dermis and is also known as the middle layer. The dermis is what holds the body together. The dermis has layers to it as well as the epidermis. There are two layers to the dermis, the papillary layer and the reticular layer. The cells of the dermis are fibroblast, macrophages, mast cells, and scattered white blood cells (wbc’s). the dermis is richly supplied with nerve fibers and BV;s. dermal BV’s is also a part of the integumentary system, dermal BV,s have converging and diverging vessels that ar...
It regulates the ratio between epithelial cells and collagen fibers as well as changes in their morphology. The imbalance of collagen metabolism and its arrangement is attributed to many factors which result in increased synthesis of collagen by fibroblasts and myofibroblasts, which in turn inhibit the activity of collagenase, leading to extensive scar hyperplasia. Matrix changes, mainly changes in fibronectin and mucopolysaccharides, result in scar stiffness. MEBO Scar Ointment can accelerate the re-arrangement of twisted collagen andreduce proliferation of fibroblasts, thus restricting scar hyperplasia. [11,13,14,15 ,21] The accumulation and synthesis of mucopolysaccharide can also be reduced once local tissues are compressed, thus reducing generation of collagen and the corresponding scar tissue. [11] Moreover, massaging the MEBO Scar ointment onto old scars can potentially reduce blood supply within scars, decrease synthesis of collagenous fiber, and,reduce α2-M (alpha 2-macroglobulin) globulin of collagenase in serum which facilitates collagenase activity and speeds up disintegration of collagen in old scars,this facility by applying MEBO scar ointment .
Currently, the limitations on research are too restricting, as researchers are limited to resources already gathered. There are sixty existing stem cell lines today, already derived from embryos. Researchers are to only use these lines. These limitations severely hinder stem cell research. The government, especially President Bush, should re-evaluate stem cell research.
The Beauty Industry being such a wide market of services and products include providing for the care of our skin, hair, selling of perfumes and cosmetics (“What is the Beauty Industry?”2014) and now developing more extensively into basic cosmetic surgery and treatments, now gives society a big opportunity to pamper and nourish themselves in more extensive ways. Throughout this essay, the branches of dermatology and dermal therapies will be explained; common skin disorders and specifically a treatment called ‘Ultrasonic Peeling’ and how it can potentially help with skin disorders imposed today will be explored and described in detail. After the investigation of what Ultrasonic Peeling is and how it works, I will also state my opinion on how well I think the treatment benefits its users, give my evaluation if I would consider using it, what I think the positives and negatives are and in scenario, assess whether it is a treatment that more salons should consider offering.
Two major types of dressing that are used for covering third degree burns and are FDA approved and recognized, Biobrane and Integra. Both of these dressings are laid and kept in place until autographing can be possible. Growing a patients skin in a lab, which is called cultured skin, is a process that helps eliminate the donor site and scarring from auto grafting. Taking a skin sample about the size of a quarter can be grown into enough skin to nearly cover all the body in about 2 to 3 weeks. The only problem with this method is that something has to cover the wounds in the meantime. This is when the Integra and Biobrane take effect. The wound could be covered with Integra or Biobrane acting as the epidermal layer of the skin until the new grown skin is ready for grafting.
...Boland, Thomas Trusk, Gabor Forgacs, and Roger R. Markwald. Organ Printing: Computer-aided Jet-based 3D Tissue Engineering. N.p., n.d. Web. 25 Nov. 2013.
Exploring the role of stem cells in cutaneous wound healing: Katherine Lau, Ralf Paus, Stefan Tiede.
Zisser, Howard C. "Abstract." National Center for Biotechnology Information. U.S. National Library of Medicine, 13 Sept. 2010. Web. 06 Jan. 2014.
To begin we will look at the integumentary system and its entire multitude of functions. The main components of the integumentary system are the skin, hair, nails, glands and nerves. For the purpose of this paper we will focus mainly on the levels of the skin and their functions. While the integumentary
This treatment is considered to be effective for the removal of acne scars. This avoids the use of taking medicines and applying ointments. However, the treatment must be done by an experienced and specially traine...
Today, if you ever needed a new lung, heart, liver, or any organ at all, you’d have to wait…..a long time. Fortunately, a new process in the field of Tissue Engineering called Bioprinting aims to fix that. Bioprinting is exactly what it sounds like – printing out biological materials from a printer. Of course, the actual process is much more complicated than just hitting print on a computer and waiting for an organ to pop out like a piece of paper. It starts with a modified inkjet printer and ink that consists of stem cells as well as many other different types of cells. Not only does it use stem cell ink, it uses a specially prepared organic paper to print the cells on. Bioprinting as a use in medicine, has the potential tol eliminate waiting lists completely, personalize each and every treatment, and eliminate the consequences of receiving an organ transplant by circumventing the need for a donor. As a consequence of being heavily invested in stem cells and being a relatively new process, bioprinting has its problems, but these complications should not prevent its progress into the future. Bioprinting holds much potential in the field of biology and medicine, such as providing a safer alternative to current organ transplants that are based on donation, helping breast cancer survivors with post-lumpectomy procedures (breast reconstruction) .
A stem cell is a cell that can duplicate into many more specialized cells. The stem cells are used to repair cornea and other parts of the human body. Stem cells have a rich supply of growth factors. Stem cells could be used as a repair system. During research at the University of Sheffield, engineers used special techniques to create a disk, loaded with stem cells, to place over the cornea. Researchers performed a treatment on a man whom suffered from a heart attack. Researchers used stem cells to help regain the lost parts of his heart. Scientists can now make dynamic changes to stem cells to create them to begin the early stages of tissue repair. Scientists are working on producing gels made from clay inserted with stem cells.
The field of regenerative medicine encompasses numerous strategies, including the use of materials and de novo generated cells, as well as various combinations thereof, to take the place of missing tissue, effectively replacing it both structurally and functionally, or to contribute to tissue healing[29]
In its nature, collagen is like the backbone of the skin and is responsible for its elasticity and structure. It’s also responsible for replacement of dead skin cells with new ones giving the skin a radiant