Thyroxine Research Paper

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Thyroxine (Eutroxrig Tablets)
Use: Thyroxine is used as a replacement or supplemental in hypothyroidism of any aetiology, except transient hypothyroidism during the recovery phase of subacute thyroiditis Specific indications include primary, secondary, and tertiary hypothyroidism and subclinical hypothyroidism. Action:
- Levothyroxine is a man-made form of thyroxine, a hormone that is produced naturally in the body by the thyroid gland.
- Levothyroxine replaces missing thyroxine in people whose thyroid glands do not produce enough thyroxine naturally.
- Thyroid hormones (such as thyroxine) play a vital role in our normal growth and development, and in the maturation of our brain, spinal cord, nerves, and bone. Thyroid hormones help …show more content…

Adverse effects:
Usually associated with over dosage and consists of the following:
- Nervousness, tremor, restlessness, anxiety, irritability
- Sweating, flushing, intolerance to heat, fever
- Headache, insomnia, sleep disturbance, poor concentration, emotional lability
- Mania, psychosis, psychotic depression
- Seizures
- Tachycardia, palpitations, cardiac arrhythmias, angina pectoris, chest pain
- Myopathy, muscle cramps and weakness eyelid lag
- Diarrhoea, vomiting, weight loss, malabsorption
- Alopecia, hyper-pigmentation
- Amenorrhoea, menstrualirre gularities, decreased libido, gynaecomastia ( male)
- Decreased glucose tolerance
Nursing consideration to Maddy’s situation:
- Assess apical pulse and blood pressure prior the medication is taken and during therapy as well. Moreover, the nurses have assessed and monitor Maddy for tachyarrhythmia and chest pain.
- Laboratory Test Consideration: Monitor TSH serum levels in the patient about 8-10 weeks after changing from one brand of medication to another …show more content…

A common treatment is to stop dose for 2-7 days then continue at a lower dose. Acute overdose is treated by induction of emesis or gastric lavage, followed by activated charcoal. Sympathetic overstimulation may be prevented by antiadrenergic drugs (beta blockers). Oxygen and supportive measures to control symptoms are also required.
Liothyronine Sodium (Tertroxin Tablets)
Use:
- Severe and acute hypothyroid states
- Myxoedema coma
Action: this medication works as supplementation or replacement of endogenous thyroid hormone. A significant effect is elevating the metabolic rate of body tissues, such as increase utilization and mobilization of glycogen or stimulate protein synthesis. Therapeutic effects, this medication works as a replacement in hypothyroidism to normalise thyroid hormone levels.
Adverse effects:
- Headache, restlessness flushing, sweating, excitability
- Diarrhoea, excessive weight loss
- Palpitation, anginal pain, tachycardia, cardiac arrhythmias
- Skeletal muscle cramps and/or

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