The quantity of organs available for transplantation is already far less than the demand, and the demand may grow substantially in close to future. For this reason, we have to think how organ function might be replaced in the future. The obstacles to applying new technologies and now those obstacles might be overcome in the developing of new approach for organ replacement. the obstacles of organ replacement might be addressed if various technologies could be pieced together in a way that exploits the advantages of each technology. Thus, nuclear cloning (the transfer of a nuclei from somatic cells of the individual to be treated into primitive enucleated cells (SCNT), allowing the reprogramming of DNA) could be used to generate embryonic stem
cells. To avoid the ethical problems of nuclear cloning and the potential immunogenicity of proteins encoded by foreign mitochondrial DNA, one might envision treating mature cells with “cloning factors” obtained from xenogeneic sources that would comparatively reprogram nuclei without transfer. The stem cells obtained in this way might be coaxed to mature by placing them in a suitable location in a xenogeneic fetus. For example, human stem cells introduced into the fetal pig can mature in normal, histotypic ways at appropriate locations in the pig fetus. The tissues that begin to mature in this xenogeneic system might be harvested, and the human cells isolated and transferred into the person to be treated so that full maturation and vascularization (i.e., organogenesis) could occur.The need of organ cloning can be overcome by better nutrition and better approaches to public health can decrease the prevalence of some of the diseases that cause organ failure and hence the need for transplantation. For example, better diet and treatment with 3-hydroxy-3-methylglutaryl coenzyme A (HMG-coA)-reductase inhibitors may prevent atherosclerosis and cardiac failure.
The cells unique nature has scientists intrigued to do research with the focus of finding a way that these cells can be used to replace patients’ injured or diseased tissues. Advancement is made to all the three types of stem cells namely embryonic stem cells, adult stem cells in addition to induced pluripotent cells. Embryonic cells are the building blocks of an embryo that is developing, and can develop into almost all body cell types. Somatic cells are found in the body tissues. They renew and regenerate in healthy bodies. The third type which is induced pluripotent is genetically modified embryo cells from skin cells.2 Research on these cells are geared towards saving humanity; a noble course.
How many people would we save if in that exact moment, we would legalize organ sales? In Joanna Mackay’s essay “Organ Sales Will Save Lives” she discusses the positive effects of legalizing the sale of human organs. Thousands of people try to find a perfect match of something that can give them years and years more of life. A match for the right heart, the right set of lungs, a kidney, and so why how come there is a barrier of uncertainty? So many people die in this world but yet seek for a chance to survive and fight the good fight. It seems inevitable but it’s the truth. Lives should be kept alive not diminished even if there is the slightest chance of survival rate. Mackay clearly explains that legalizing organs can save thousands of lives. But at what cost is the donor willing to go? In Mackay’s essay, legalizing organs would be a beneficial act, in which it would save lives, great way to
Mandatory organ donation would consist of passing a law wherein the government mandates organ donation from every person who dies. In other words, unless a person chooses to opt out of the donation process, he or she is automatically an organ donor by law. According to Spranger (2012), organ donation is a gift of life and by donating organs after we die, we can literally bring someone back to life. It is a pretty good gesture; however, it could be argued that everyone should want to donate their organs when they die and consent for donation should be speculated. One of the arguments against mandatory organ donation is you don't own your body once you die. The assumption is that the body would belong to the government and not to the family.
In the world we’re living in today, many kinds of diseases, infections, and viruses are continuously arising. At the same time, scientists are untiringly researching about how we can prevent or cure them. Unfortunately, millions of people have been affected and sick that some of their organs fail that results to the need of organ replacement. Many people have died because no organs have been available to provide the need of organ replacements. The shortage of organ replacement has been a bioethical issue since then and it seems like no solution has been available. However, due to the studies scientists have been conducting, they found the most possible answer to this issue – Xenotransplantation. It hasn’t become very popular all over the
The uncontainable despair of the weeping and screaming parents entering a room full of body bags containing the altered remains of their children. In a room drained with blood and surrounding fridges for the maintenance of the ejected organs, everything seems miserably surreal(“Children Kidnapped for Their Organs”). This is only one of the discovered cases of the daily dozens of people killed for organ harvestation. Adding up to ten thousand illegal operations in 2012 which translates to hourly sales (Samadi). These abhorrent acts add up as crimes against humanity which are triggered by a numerous amount of reasons; in order to stop these constant atrocities we must uncover the root of the causes.
Why are organ sales illegal? Donors of blood, semen, and eggs are often compensated. Why not apply the same guide lines to organs? Joanna Mackay(2013) explains in her article Organ Sales Will Save Lives, “About 350,000 Americans suffer from end-stage renal disease.”(p. 120) At this stage of renal disease, the kidneys are no longer able to remove enough wastes and excess fluids from the body. Therefore, you would need dialysis or a kidney transplant.
Currently 70,000 Americans are on the organ waiting list and fewer than 20,000 of these people can hope to have their lives saved by human organ transplantation.1 As a result of this shortage, there has been a tremendous demand for research in alternative methods of organ transplantation. Private companies are racing to develop these technologies with an estimated market of six billion dollars.2 Xenotransplantation, or cross-species organ transplantation, appears to be the most likely solution in the near future, and cloned pigs are the main candidates. Pigs and humans have remarkable similarities in physiology, which along with cloning makes pigs strong possibilities for organ donors. A controversial alternative method involves the use of genetically altered headless human beings as organ donors. Although this method may not be developed for some years, scientists are already discussing the necessary technologies. Whether the solution is the cloning of a pig or a human, organ farms may provide us with a solution to our ever-increasing need for donors.
One single organ donor can save the lives of eight people and that same donor can help to improve health conditions of fifty other people as said by an article on facts about donation. Organ donation is when a living or deceased person's organs are taken out by medical physicians and surgically inserted into another person's body to help improve their health condition. The receiver and donor of the organ are not the only people affected by the transplant. Families of the donor will often become relieved knowing that their loved one will be continuing to help needy people even after they are gone and the families of the receiver will also sleep better knowing that there is still a chance that someone could help the medical status of their loved one. Organ transplant has also overcome many scientific challenges. Jekyll’s actions in Dr.
When exploring the possibilities that humans will be faced with in the not too distant future in which humans are transformed into something that is human but different, the Trans-human. We see a future offering genetic manipulation, replace parts grown and used when needed, we can even see the possibilities of regeneration. The one that I contend will be the first and probably the fastest path to the future of mankind is the machine brain interface. I define this idea as any device that is not native to the biological human that interacts directly with the brain producing results that either enhance a person’s natural ability or somehow bypasses limitations that injury or disease has inflicted the individual with (paralysis). The closest
In addition to its medicinal benefits, animal cloning could be used to produce tissues or organs for transplants (15). This can be done by culturing "embryonic stem cells," or "primitive cells that appear between ...
There have been numerous developments in the subject of biotechnology. One of these advancements contains xenotransplantation. It is the transplantation of living tissues, cells or organs from one species to another. For example, it covers transplantation of vital organs like heart, kidney and also skin graft, bone transplant s, corneal transplants. The purpose of human xenotransplantation is that it proposes a possible solution for the problem of the shortage in human organs because the number of accessible organs is not equal to the number of needed organs. For instance, according to M. Anderson’s article the number of people waiting for an allotransplant (it refers to a same-species transplant such as human-to-human.) is progressively increasing without organ donations. In addition, approximately half of those demanding an organ transplant will die while on the organ donor waiting list (Anderson 205). Furthermore, it can also be used to treatment other illness where there is a scarcity of human material accessible such as Alzheimer, Parkinson, diabetes. As we can see, in theory xenotransplantation provides good solution for human beings, however, when look at the history we cannot see same good things. For instance, in 1964, a scientist who is Keith Reemstma transplanted a chimpanzee kidney into a human with end period nephritic disease, increasing the participator’s life a record nine months (Anderson 205). However, there is another case which is Baby Fae. In this case doctors transplanted a baboon hearth into the baby and he survived just four w...
Cloning is another new medical advance that allows for many great possibilites. Exact organ matches for organ transplants could be made through cloning. Animal...
Recent discoveries involving cloning have sparked ideas of cloning an entire human body (ProQuest Staff). Cloning is “the production of an organism with genetic material identical to that of another organism” (Seidel). Therapeutic cloning is used to repair the body when something isn’t working right, and it involves the production of new cells from a somatic cell (Aldridge). Reproductive cloning involves letting a created embryo develop without interference (Aldridge). Stem cells, if isolated, will continue to divide infinitely (Belval 6). Thoughts of cloning date back to the beginning of the twentieth century (ProQuest Staff). In 1938, a man decided that something more complex than a salamander should be cloned (ProQuest Staff). A sheep named Dolly was cloned from an udder cell in 1997, and this proved that human cloning may be possible (Aldridge). In 1998, two separate organizations decl...
One of the most beneficial aspects to cloning is the ability to duplicate organs. Many patients in hospitals are waiting for transplants and many of them are dying because they are not receiving a needed organ. To solve this problem, scientists have been using embryonic stem cells to produce organs or tissues to repair or replace damaged ones (Human Cloning). Skin for burn victims, brain cells for the brain damaged, hearts, lungs, livers, and kidneys can all be produced. By combining the technology of stem cell research and human cloning, it will be possible to produce the needed tissues and organs for patients in desperate need for a transplant (Human Cloning). The waiting list for transplants will become a lot shorter and a lot less people will have to suff...
Artificial organs are devices that are used to replace damaged organs. They might be permanent or temporary. The goal of artificial organs is to save the life of a patient as soon as possible. The human body is not simple machine, and still remains a puzzle even after years of medical research. . All the organs in the body work separately so we have to make sure the organs still healthy. However, there are some ailments if not cured on time, can cause organ lack of success, which may further lead to complications and in some cases d...