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Literature review on Polio
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Literature review on Polio
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Diseases can affect populations and regions throughout the world. However, the low-income countries are affected more due the lack of capacity and training to address these challenges. Similarly, polio may not seem an issue in the developed countries, yet it remains endemic in many countries such as s Afghanistan, Pakistan, and Nigeria1. Oral polio vaccine (Sabin) or OPV is the vaccine of preference in such endemic areas owing to easier administration. Not only can it be easily administered, but it can also be dispensed by workers or volunteers without much formal training2. Thus, OPV administration does not require a highly trained medical worker /nurse/physician. Moreover, oral polio vaccine is an inexpensive option. Unlike the Inactivated Polio Vaccine (IPV)/Salk, Oral Polio vaccine does not require sterile syringes. Furthermore, OPV offers a longer immunity coverage as compared to the IPV2. It will be pertinent to mention that the OPV vaccine functions by stimulating circulating antibodies and developing resistance to infection of the For instance, there is a chance of an outbreak of vaccine-derived poliomyelitis (VDPV)2. In the past, OPV has been responsible for a few outbreaks of vaccine-derived polio. Moreover, OPV is not recommended for immunocompromised persons or individuals currently on immunosuppressant therapy. Due to of the risk as mentioned above of VDPV, in 2000, most European countries and United States discontinued using OPV and would only administer IPV2. Moreover, wild-type poliovirus had already been effectively eliminated in these countries. In developing countries, the benefits of OPV far outweigh the risks associated with it, thus making it an ideal choice. However, in the United States exists a changed scenario and polio is not endemic and to prevent any case of VDPV, it may be a safer option to administer
Polio, formerly known as poliomyelitis, an infectious viral disease that affects the central nervous system and can cause temporary or permanent paralysis. A debilitating disease that was once the affliction of our very own republic. David Oshinsky’s Polio: An American Story chronicles polio’s progression in the United States, a feat it does quite well throughout the course of the novel.
Moreover polio is a deadly disease that is caused by a highly contagious virus entering the nervous system in the brain or spinal cord causing temporary or permanent paralysis. There are three
Polio: An American Story describes a struggle to find a vaccine on polio through several researchers’ lives, and over the course of many years. The second thesis is the struggle between Salk and Sabin, two bitter rivals who had their own vaccine that they believed would cure polio. The author David M. Oshinsky, is describing how difficult it was to find the cure to a horrifying disease, which lasted from the Great Depression until the 1960’s. Oshinsky then writes about how foundations formed as fundraisers, to support polio research. Lastly, the author demonstrates how researchers were forced to back track on multiple occasions, to learn more about polio.
Jonas Salk, a virologist at the National Foundation for Infantile Paralysis (NFIP), used inactivated viruses (virus particles grown in culture and then killed by a form of heat) to create a polio vaccine. Salk drew blood from about two million children, which the NFIP checked for immunization. Through the collection of many HeLa cells and trial and error, the polio vaccine was ready in a year.... ... middle of paper ... ...
Poliomyelitis was the term used by doctors to describe the condition in which the gray (polios) anterior matter of the spinal chord (myelos) was inflamed (-itis). Until a cure was discovered, no one had the slightest idea where "polio" had come from or why it paralyzed so many children. People learned later that, oddly enough, it was the improved sanitary conditions which caused children to be attacked by the virus. Since people were no longer in contact with open sewers and other unsanitary conditions which had exposed them to small amounts of the polio virus as infants, when paralysis is rare, the dis...
In the United States there was a vicious enemy everyone feared. In the 1950s the United States was under attack by the ruthless Poliomyelitis virus. Americans lived in constant fear of their children contracting this horrible virus that left many children paralyzed. During the outbreaks in the 1950s foundations were created to fund research and create awareness to help find a way to eradicate the virus. Americans become focused on doing anything in their power to fight this virus off. Jonas Salk’s Exploration of Medicine and research led to the creation of the Polio vaccine that united the country, prevented further outbreaks, and introduced a new form of treatment which has limited the fatality of polio infections today.
Polio is a viral disease. It cripples thousands of people and infects even more every year. Even though millions are inoculated, and the polio disease has been successfully purged from hundreds of countries still thousands of people and developing countries are infected and still people are dying. According to the World Health Organization (WHO) polio affects the Central Nervous System, or CNS; by infesting the intestines and transmitting it into the nerves thought the blood vessels. There the virus spreads through the nerve cells to the brain stem or other motor units, while forever damaging the nerves.
Vaccination was first introduced globally for small pox and later on extended to other communicable diseases which are now known as vaccine preventable disease. Vaccination is beneficial both for individuals and community. This bring us to the ethical dilemma - Vaccination of a healthy child with the intention of protecting both the individual child and the community at the same time exposing the child to the theoretical risk of exposure to disease products whether live, attenuated or killed. There was a time when people never questioned the government or their physicians. Now because of more public awareness and accessibility to medical information, they are questioning the safety aspects of vaccines.
Vaccines have been used to prevent diseases for centuries, and have saved countless lives of children and adults. The smallpox vaccine was invented as early as 1796, and since then the use of vaccines has continued to protect us from countless life threatening diseases such as polio, measles, and pertussis. The Center for Disease Control and Prevention (2010) assures that vaccines are extensively tested by scientist to make sure they are effective and safe, and must receive the approval of the Food and Drug Administration before being used. “Perhaps the greatest success story in public health is the reduction of infectious diseases due to the use of vaccines” (CDC, 2010). Routine immunization has eliminated smallpox from the globe and led to the near removal of wild polio virus. Vaccines have reduced some preventable infectious diseases to an all-time low, and now few people experience the devastating effects of measles, pertussis, and other illnesses.
Why would anyone want to leave their child at risk of developing a sickness that could easily be preventable? Some people believe that vaccines do not work and are only harmful; they are wrong. Vaccines can be helpful not only to the child of the concerned parent, but also the children of other parents as well. Parents should vaccinate their children because it prevents illnesses, rarely has negative effects, and vaccines have increased the human lifespan. If an illness is preventable, parents should ensure that their children are getting the medical protection available.
In Conclusion, Understanding Polio’s etiology, history and epidemiology, as well as proper treatments will assist in avoiding its return. Although polio has been known to substantially affect a wide population in a small amount of time, eradication of this disease may also be accomplished in a short period of time. Scientists and medical professionals continue to research this disease in order to better understand and maintain it for many years to come. There are still aspect of the disease people do not understand that may be vital for the future of a polio-free world.
Spencer, Steven M. "Where Are We Now on Polio?" Saturday Evening Post 10 Sept. 1955: 19+. MasterFILE Premier. Web. 6 Mar. 2014.
America looks at disease as a war. Illness is the enemy, vaccinations are the weapons, and the unfortunate cost is that some innocent civilians may lose their lives. A vaccine is a substance used to provide immunity against a disease. In some cases, vaccines have done more harm than good. Ignoring this fact, vaccines are mandatory in every state, and some states are trying to take away the parent’s right to deny them. The disadvantages, diseases, and disabilities caused by vaccines justify the parent’s right to decide against the risk of vaccination.
Poliomyelitis, also known as Polio, is a highly contagious disease caused by a virus that attacks the nervous system. Most victims to this disease are younger than five years of age; they are more likely to get this disease than any other age group. Out of two hundred people infected with the polio disease one is most likely to result in paralysis. The Polio Virus has decreased greatly since the Polio Vaccine was developed. In 2010 a WHO (World Health Organization) pole reported only 1,352 cases worldwide. Since the Polio Vaccine was developed the U.S has not has a single Polio case since 1979.
Preventing diseases is every countries’ responsibility, whether they are poor or rich. Poor countries lack the knowledge and the money to gain, and expand medical resources. Therefore, many people are not been able to be cured. For wealthy countries, diseases are mutating at incredible speeds. Patients are dying because drug companies do not have enough data to produce vaccines to cure patients. When developed countries help poor countries to cure their people, the developed countries could help underdeveloped countries. Since developed countries can provide greater medical resources to poor countries, people living in the poor countries could be cured. As for the developed countries, they can collect samples from the patients so that the drug companies can produce new vaccines for new diseases. When trying to cure diseases, developed countries and poor countries would have mu...