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Pharmacology neurotransmitters
Pharmacology neurotransmitters
Functions and dysfunctions of neurotransmitters
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Hypothetically speaking, if patients asked their neurologists to explain what the nervous system is, how would typical neurologists respond to such a question? For the most part, patients ' question on what is the nervous system maybe a simple question for neurologists. In this instance, neurologists possibly explain to patients that the nervous System serves as a communication network that operates and coordinates the body 's activities. Operating and coordinating the body 's activities includes the nervous system to monitor thoughts, learning processes, body temperature, and altering the heart rate-- To name a few of the nervous system 's responsibilities. During the topic of discussion on the nervous system, patients asked their neurologists …show more content…
Located in the nervous System region, the formation of Synapses begins in the Synaptogenesis stage. As Cohen-Cory (2002) noted that during the Synaptogenesis stage, Synapses are established, matured, and stabilized (p. 770). The beginning stages of the development, maturity, and stabilization of Synapses occurs in the Central nervous system (CNS). In the following manner, Synapses are established and matured in the CNS, Synapses stabilizes it neurons by trading off between the axons and dendrites. Aside from the Synaptogenesis stage of the formation, maturity, and the stabilization of synapses, these type of neuronal structures face the process of elimination. Predominantly, the elimination of synapses according to Cohen-Cory (2002) is, "... A process that requires intimate communication between pre-and-postsynaptic partners" (p. 770). To conclude on the elimination of the excess synapses in the CNS, primarily occurs during the chemical synapse of the Neuromuscular …show more content…
First, the Electrical synapse relies on having two cells spanning across two membranes and the synaptic cleft between them (Shepard and Hanson, 2014, para. 2). Overall, the purpose of the Electrical synapse for the nervous system is for the synapse to carry out impulses and reflexes. On the contrary, the neuronal structure of the Synapse’s Chemical synapse involves the role of neurotransmitters in the nervous system. Located between the nerve cells, the gland cells, and the muscle cells, the Chemical synapse allows neurons for the CNS to develop interconnected neutral circuits. According to Davis (2007), “Interconnected logical computations that underlie perception and thought” (p.17). Generally, regarding the Chemical synapse’s role in the nervous system, this classification of the Synapse has a valuable role on how drugs affect the nervous system actions on synapses. As a result, the activity of the neurotransmitters becomes the key contributor for the Chemical synapse to effectively process drugs in the nervous system and throughout the human autonomy. Defines as a chemical released across the Synapse of a neuron, neurotransmitters manipulates the body to believe the drugs are neurotransmitters as well (Davis, 2007, p. 19). Significantly, the role of drugs in the human body help prevents the obliteration of neurotransmitters in the nervous system (Davis, 2007, p. 19).
So you could find a multitude of acetylcholine in each synaptic vessel. The vesicles' contents are then released into the synaptic cleft, and about half of the acetylcholine molecules are hydrolyzed by acetylcholinesterase, an enzyme that causes rapid hydrolysis of acetylcholine. But soon, there are so many acetylcholine molecules that this enzyme cannot break them all down, and the remaining half reach the nicotinic acetylcholine receptors on the postsynaptic side of the
Chemistry of Psilocybin and Synaptic Transmitters Involved Psilocybin is a type of hallucinogenic mushroom that is ingested by eating the raw fungi. The mushroom can also be made into a tea and drunk. In some of the later studies done on psilocybin, the drug was synthetically produced and then either inhaled or injected by an IV. The drug enters the blood stream and can cross the blood brain barrier because of it relative metabolic similarity to serotonin (Fuller 1985). This means that since psilocybin is chemical resemblance to the neurotransmitter serotonin, psilocybin can trick the protein channels embedded in the membrane of the blood vessel and pass through as if it were serotonin and not a drug.
The presynaptic terminal stores high concentrations of neurotransmitter molecules in vesicles, which are tiny nearly spherical packets. These molecules are then released by depolarization. Depolarization opens voltage-dependent calcium gates in the presynaptic terminal. After calcium enters the terminal, it causes exocytosis, which is the burst of release of neurotransmitters from the presynaptic neuron. After its release from the presynaptic cell, the neurotransmitter diffuses across the synaptic cleft to the postsynaptic membrane, where it attaches to the receptor.
The human nervous system is divided into two parts, the central nervous system and the peripheral nervous system. The central nervous system, CNS, is just the brain and spinal cord. The peripheral nervous system, PNS, includes the nerves and neurons that extend outwards from CNS, to transmit information to your limbs and organs for example. Communication between your cells is extremely important, neurons are the messengers that relay information to and from your brain.
Neurotransmitters can also produce their effects by modulating the production of other signal-transducing molecules ("second messengers"messengers") in the post-synaptic cells (Cooper, Bloom and Roth 1996). Nine compounds -- belonging to three chemical families -- are generally believed to function as neurotransmitters somewhere in the central nervous system (CNS) or periphery. In addition, certain other body chemicals, for example adenosine, histamine, enkephalins, endorphins, and epinephrine, have neurotransmitter-like properties, and many additional true neurotransmitters may await discovery.
The most commonly abused substances are Nicotine, Inhalants, Alcohol, Cocaine, Amphetamines, Prescription medications, Heroin, Ecstasy and Marijuana. 1a(National Institute on Drug Abuse, 2011) Initially, a person may find themselves using substances voluntarily and with confidence that they will be able to dictate their personal use. However, over the period of time that drug use is repeated, changes are taking place throughout the brain, whether it is functionally or structurally. Drugs contain chemicals that enter the communication system of the brain and disturb the way in which nerve cells would typically send, receive, and process information. The chemicals within these drugs will cause a disruption to the communication system by either imitating the brain’s natural chemical messengers or by over-stimulating the brains “reward system” by sending mass amounts of dopamine. As an individual prolongs his or her use of these substances, they may develop an addiction.
Almost all animals have a nervous system. Neurons bundle together to form nerves. The purpose of the nervous system is to coordinate all activities of the body, and enables the body to respond and adapt to changes both inside and outside. The central nervous and the peripheral nervous systems are very similar but different at the same time. The CNS is made up of the brain and spinal cord and functions mainly to process information and determine the appropriate responses. The central nervous system receives sensory information, figures out a response, and initiates a motor response if appropriate. The CNS is protected by the skull, vertebral column, and a membrane. The spinal cord provides communication between the brain and the peripheral nerves
The nervous system includes the brain and spinal cord of the central nervous system and the ganglia of the peripheral nervous system. The functional unit of the nervous system is a neuron. It is estimated 100 billion neurons reside in the brain with some neurons making anywhere between 10,000 to 100,000 connections with other cells! A distinctive class of neurons, mirror neurons discharge both when the individual executes a motor action and when he/she observes another individual performing that same or similar action. These mirror neurons were discovered by neurophysiologists in the 1990s at the University of Parma, Italy. Using macaque monkeys, these researchers found that neurons of the rostral part of the inferior premotor cortex were activated both when the monkey made goal-directed hand movements (grasping, holding, & tearing) and when the monkey observed specific hand movements done by the experimenters (Pellegrino, et al., 1992). In a monkey’s inferior frontal and inferior parietal cortex, it is estimated that about 10% of neurons have “mirror” properties.
The purpose of this paper to examine the evolution of the human brain that distinguishes them from other species based on the traits that humans possess: such as language, emotional complexity and consciousness. The significance of traits are due to adaptations in humans to promote the survival of our ancestors. Professor Hamilton (2012) discusses that the evolution of the human brain starts with the idea of the Triune brain, proposed by MacLean, whereby the human brain is made up of three parts: Reptilian, Paleo-mammalian, and Neo-mammalian. Animals with the neo-mammalian brain have a more complex brain compared to the other parts, since this is where the neocortex evolved. Humans essentially have this higher brain function which is responsible for our ability to think, make decisions, promote agency, and the ability to relate with each other. This concept fits into the evolutionary process since it shows how the complex the brain has become through evolutionary processes. In essence, as humans, we “have a rich, evidence-based understanding of our behavior that can lead us to plan to be ‘better’ or ‘more successful’ people” according to Professor Hamilton (2012). Thus, shows how evolution plays a significance in understanding human behavior and comparing humans with other species.
Synaptic transmission is the process of the communication of neurons. Communication between neurons and communication between neuron and muscle occurs at a specialized junction called synapses. The most common type of synapse is the chemical synapse. Synaptic transmission begins when the nerve impulse or action potential reaches the presynaptic axon terminal. The action potential causes depolarization of the presynaptic membrane and it will initiate the sequence of events leading to release the neurotransmitter and then, the neurotransmitter attaches to the receptor at the postsynaptic membrane and it will lead to the activation of the postsynaptic membrane and continue to send the impulse to other neurons or sending the signal to the muscle for contraction (Breedlove, Watson, & Rosenzweig, 2012; Barnes, 2013).
Physical Development carries two key perspectives, nature and nurture. Both perspectives can be supported in many mays.
The nervous system’s main function is to coordinate all of the activities in the body. The main organs are the cerebellum, which controls and coordinates movement. The cerebrum, is the center for conscious thought, learning, and memory. The last main organ is the brain stem. The brain stem keeps the automatic systems in your body working. Problems of the nervous system include, epilepsy, Alzheimer’s, and multiple sclerosis. You can care for your nervous system by wearing a seatbelt, wearing a helmet, and by not using drugs or alcohol. Something very confusing about the nervous system is that the left side of human brain controls the right side of the body and the right side of the brain controls the left side of the body!
Physical and motor development are two similar but different areas that describe child development. Physical development encompasses all of the various changes a child's body goes through. Those changes include height, weight, and brain development. Motor development is the development of control over the body. This control would involve developing reflexes such as blinking, large motor skills like walking, and fine motor skills like manipulating their fingers to pick up small objects like Cheerios. It is important to objectively study physical and motor development in children to gain knowledge on what characteristics are considered typical for each age and stage of development. This will enable me to be aware of when a child or children are developing at an irregular pace, and devise recommendations or find experiences and other resources that can aid in stimulating their development and to work towards closing achievement gaps. This particular assignment was to observe the selected child and reaffirm the importance of studying physical and motor development, and to develop ideas on how to involve it in my work as an early childhood professional.
The nervous system is composed of all nerve tissue in the body. This organ system forms a communication and coordination network between all parts of the body. It plays a major role in everyday activities such as breathing, walking even blinking. It is made up of nerve tissues to receive and transmit stimuli to nervous centers and initiate response. Neurons are nerve cells that transmit signals from one location of the body to another. With damage to the nervous system the body would not be able to function properly. The body has to be well taken care of in order to insure proper regulation. The two anatomical divisions that work hand in hand to help regulate the nervous system are the central and peripheral nervous system. According to the Campbell’s seventh edition biology book the nervous system is the most intricately organized data processing system on earth. It is a complex collection of nerves and specialized cells.
First, what is the nervous system? The nervous system is the connection between nerves and cells that take a message to the brain and the spinal cord. This system is divided into the central nervous system (CNS), which contains the brain and the spinal cord, and the peripheral nervous system (PNS), which consists on sensory and motor neurons. The PNS has its own nerves that connect to the CNS sensory organs, blood vessels, etc. This part of the system is all around the body, except for the center 8 in the spinal cord and brain). The CNS, as before said, consists of the spinal cord and the brain, it is