The Incentive-Serensitization Theory

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Heroin addiction is a significant problem in the United States, but particularly Ohio. According to the CDC, “Heroin-related deaths more than tripled between 2010 and 2015, with 12,989 heroin deaths in 2015.” (“Understanding the Epidemic”). Heroin addicts often start out addicted to prescription painkillers, and transition to heroin when the prescription drugs become too difficult or expensive to obtain. Many addicts in the United States are unable to get affordable treatment, which is a likely cause of the rise of deaths. The United States should work to expand access to addiction treatment programs. Heroin addiction is a serious issue across the United States. Over 10,500 deaths per year are attributed to heroin, and even more are attributed …show more content…

Opiates are used as painkillers because they bind to opioid receptors on nerve cells in the brain and decrease the feelings of pain, as well as increasing dopamine levels. This floods the brain’s reward system, leading to addiction. (Ouzir, 60). One theory that attempts to explain why people get addicted to drugs is the incentive-sensitization theory. Mounir Ouzir writes about this: “The incentive-sensitization theory asserts that the motivational properties of drugs are related directly to their subjective pleasurable effects which create adaptations in the brain (Robinson and Berridge, 1993, 2000).” (Ouzir, 60). The opioid receptors are responsible for feelings of comfort and happiness, but too much stimulation leads to drowsiness and potentially death. Additionally, if opioids are used too frequently, the body stops producing natural opioids, leading to withdrawal symptoms when the drugs are no longer used (Volkow). This also leads to desensitization of the natural opioid system, which causes a tolerance to build and leads to dependence (Ouzir, …show more content…

However, the scientific community is largely in consensus that addiction should be classified as a brain disease. As discussed earlier, Ishani Deb’s study suggests that addiction is heritable, similar to many diseases (Deb, 489). Nora Volkow also refers to addiction as a disease: “The transition from misusing prescription opioids to using heroin may be part of the natural progression of disease in a subset of users.” (Volkow). Finally, Mounir Ouzir writes, “Drug addiction is now believed to be a brain disease that affects the physiology of certain brain regions and causes severe alterations in behavior, memory and neural cell life and may even cause neuronal cell death (Mewes et al., 2010; Koob and Volkow, 2010; Gold et al., 2009; Fowler et al., 2007).” (Ouzir,

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