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Roles and importance of genetics in our society
Future use of the human genome project
Impacts of human genome project in society
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Is it possible to eradicate disease entirely? A half-century ago, little was known about how disease was affected by genetics. In 1953, James Watson and Francis Crick discovered the double helix structure of DNA. In the mid 1970’s, ways were developed to determine the order, or sequence, of the chemical letters in DNA. The Human Genome was completely unknown to man until 1990, when the National Institutes of Health (NIH) and the Department of Energy teamed up with international partners to complete the entire 3 billion base pairs of the Human Genome. The goal of this project was to understand the genetic factors in human disease and to hopefully find ways to diagnose, treat, and prevent disease. The Human Genome project has supported an Ethical, Legal and Social research program to address the many issues that might arise from this study. The Human Genome Project should continue because it has the potential to unlock the cure to countless diseases.
In April 2003, researchers successfully completed the Human Genome Project, more than two years ahead of schedule. The Human Genome Project has already led to the discovery of more than 1,800 genes that cause disease (“NIH Fact Sheets…”). As a result of the Human Genome Project, researchers can find a gene suspected of causing an inherited disease in a matter of days, rather than the years it would have taken before. “One major step was the development of the HapMap. The HapMap is a catalog of common genetic differences in the human genome. The HapMap has accelerated the search for genes that have a say in common human disease, and have already produced results in finding genetic factors involved in conditions ranging from age-related blindness to obesity”(NIH Fact Sheet). The Can...
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...e, not only humans are being affected by this project. As a result of the Human Genome project Americans can make our crops more resilient with increased size. Why stop there? The Human Genome Project could be used to affect our livestock, making them mature faster and even making organs more compatible with humans (Narcisse).
The Human Genome Project is essential for the human race to advance. With the ability to decimate human disease and even boost food resources, people will increase life expectancy alongside decreasing the percent of people around the world who go hungry each day. There can even be limits placed on Legal aspects of The Human Genome Project results that appease civil rights activists and will preserve ethics and diversity while still improving mankind. Humans will never have to fear disease or hunger. The future looks bright for all of mankind.
...hich inherited traits, such as those for genetic disease, can be tracked over generations. Throughout out the course of human development, scientists will continue to find new new ways to help the human race through the discovery of the human gene inside of each of us, its uses, as well as complications, that can help the survival of our species.
The more we know about genetics and the building blocks of life the closer we get to being capable of cloning a human. The study of chromosomes and DNA strains has been going on for years. In 1990, the Unites States Government founded the Human Genome Project (HGP). This program was to research and study the estimated 80,000 human genes and determine the sequences of 3 billion DNA molecules. Knowing and being able to examine each sequence could change how humans respond to diseases, viruses, and toxins common to everyday life. With the technology of today the HGP expects to have a blueprint of all human DNA sequences by the spring of 2000. This accomplishment, even though not cloning, presents other new issues for individuals and society. For this reason the Ethical, Legal, and Social Implications (ELSI) was brought in to identify and address these issues. They operate to secure the individuals rights to those who contribute DNA samples for studies. The ELSI, being the biggest bioethics program, has to decide on important factors when an individual’s personal DNA is calculated. Such factors would include; who would have access to the information, who controls and protects the information and when to use it? Along with these concerns, the ESLI tries to prepare for the estimated impacts that genetic advances could be responsible for in the near future. The availability of such information is becoming to broad and one needs to be concerned where society is going with it.
The age of genetic technology has arrived. Thanks to genetic technological advancements, medical practitioners, with the help of genetic profiling, will be able to better diagnose patients and design individual tailored treatments; doctors will be able to discern which medications and treatments will be most beneficial and produce the fewest adverse side effects. Rationally designed vaccines have been created to provide optimal protection against infections. Food scientists have hopes of genetically altering crops to increase food production, and therefore mitigate global hunger. Law enforcement officers find that their job is made easier through the advancement of forensics; forensics is yet another contribution of genetic technology. Doctors have the ability to identify “high-risk” babies before they are born, which enables them to be better prepared in the delivery room. Additionally, oncologists are able to improve survival rates of cancer patients by administering genetically engineered changes in malignant tumors; these changes result in an increased immune response by the individual. With more than fifty years of research, and billions of dollars, scientists have uncovered methods to improve and prolong human life and the possibilities offered by gene therapy and genetic technology are increasing daily.
The debate over the importance of a Human Genome Project can be cleared up by looking at what the human genome actually is, and why knowing its DNA sequence can be beneficial to the scientific and the human community. The human genome is made up of about three billion base pairs, which contain about 100,000 genes. The 100,000 genes in the 46 human chromosomes only account for a small total of the DNA in our genome. Approximately 10 percent of our DNA make up these genes in our genome, these genes are what is actually encoded for and used by our body to make vital proteins needed for everyday life. The remaining 90 percent of our three billion base pairs are repeated sequences between genes that do not encode for any particular product. These repeated sequences account for the reason why 99 percent of any humans DNA is identical to another human's (1). With this knowledge many people believe it is not worth the time or money to sequence the entire human genome when only a small percent is used to encode for proteins. However, by sequencing the whole genome researchers will no longer have to do a needle in the haystack type of search for small genes, like the one found on chromosome four that is responsible for Huntington's disease (4). Also, knowing the complete human DNA sequence will allow scientists to determine the role and importance of the repeated DNA, non-protein encoding, sequences in our body.
In 1990, the first great stride of genetics took place. This was called the Human Genome Project, a large-scale operation that was designed to understand the human genome (genetic structure). Since its commencement, there have been many leaps and bounds that have taken place. For certain genetic issues that we once knew nothing about, we no...
In the past, the discovery of human disease genes has historically been an arduous undertaking. Extensive and exhaustive studies of genetic inheritance and pedigrees in generations of families led to the discovery of the color blindness gene on the Y chromosome in the early 1990's. As more biological tools became available, the pace of gene discovery increased. However, much of the biological laboratory practices were still rooted in intensively manual procedures. With the introduction of computing power in the mid-1980's, disproportionate amount of resources were being applied to hundreds of individual gene discovery efforts, such as Huntington's Disease and muscular dystrophy. It was with this realization that a large-scale effort at mapping the human genome was undertaken and in 1990, the Human Genome Project was deemed possible and launched officially by the National Institute of Health (Pollack 1,2).
Modification of the human genome will occur as a natural result of genetic research, even if it does not directly pertain to reshaping human DNA. In areas such as agriculture and breeding, genetics already plays an important role in determining success. In just a few decades, genetically altered crops went from laboratories to farmland, foreshadowing the success of similar projects in humans in the future. Techniques scientists use to adjust the nature of plants are antecedents to slightly modified procedures that are today used to change the DNA of animals. In Redesigning Humans, Gregory Stock describes a specific way genetics is already used to determine traits, saying, “This is not pie-in-the-sky genetic design. Capecchi’s lab has already used the technique…in a mouse chromosome” ...
The genetic technology revolution has proved to be both a blessing and a blight. The Human Genome Project is aimed at mapping and sequencing the entire human genome. DNA chips are loaded with information about human genes. The chip reveals specific information about the individuals’ health and genetic makeup (Richmond & Germov 2009).The technology has been described as a milestone by many in that it facilitates research, screening, and treatment of genetic conditions. However, there have been fears that the technology permits a reduction in privacy when the information is disclosed. Many argue that genetic information can also be used unfairly to discriminate against or stigmatize individuals (Willis 2009).
Can you imagine knowing your own genetic code? Going into the doctor for a routine physical and leaving with the knowledge of your genetic downfalls so that you may prevent disease and cancers. This may seem unbelievable but it is likely to be implemented in the near future. Since the start of the human genome project, the medical community has been anxiously awaiting its completion because the applications it has to this field are obviously enormous. However, we still have much to learn about genetic variability and the information we gain can be used to prevent, repair, and eradicate illness.
It was not that long ago that there was an age of no internet or computers. Life around the world has changed dramatically in the past thirty years. Technology has advanced at faster rate than ever before. We now know about many new things including humans including our DNA. It seems as though, the more we learn about the make up of our bodies, the more we are learning how to manipulate them. Do we want to let science take over our natural way of life? Russell Powell of the Journal of Medicine & Philosophy agrees that there is a common worry that humans could be harmed by genetic engineering of humans. The problem, Powell says, could potentially lead to the extinction of human life. By reducing human genetic diversity, we could end up with a biological monoculture that may increase our susceptibility to deadly diseases.
Assessing the consequences of the information that the Human Genome Project may yield must be taken into consideration; the medical benefits must be weighed on a balanced scale with the ethical and moral ramifications to properly size up what we will do in the future. Residents of the Rio Grande Valley must be prepared to deal with the positive and negative aspects of this modern revolution that we call genetics.
In June 2000, the publicly funded Human Genome Project (HGP) and the private firm Celera Genomics Inc. announced that they had completed sequencing the human genome. This unprecedented accomplishment is expected to enable doctors to diagnose, treat and even prevent numerous genetic diseases. As these two entities worked on sequencing the human genome, there was also a separate and less publicized race to patent as many human genes as possible.
You may think that you have full control over your body, the way you look, how you dress, and even how you do your own makeup. You have control over your hair color, how much knowledge you have, and even how strong you can be, but could you imagine having control over how tall you would like to be, the color of your eyes, and potentially the color of your very skin? Can you imagine altering EVERY aspect of yourself, including the omission of disease? These are some of the questions that the USDE hopes to find solutions to through The Genome Project. The Genome Project has been an ongoing project since 1990 and was finally completed on April 14th 2003.
In April 2003 this project was successfully completed with a high-quality version of the full human genome available for public view. Advantages: Genomics and the Human Genome Project are having huge positive effects on the economy of many places like China, Germany, France, Spain and many more. The Human Genome Project has brought in over $800 million dollars since 1990 and given about 4 million jobs since 2003, which has enabled millions of people to stay off the streets and support their families.
Another area of medical advancement is genetic engineering. Genetic engineering will detect and possibly stop diseases before birth. Many diseases are associated with specific genes that can be checked for disease and replaced if dysfunctional. Genetic testing has already revealed genetic mutations that cause hypertension, heart disease, diabetes, osteoporosis, colon cancer, polycystic kidney disease, Alzheimers disease, and others. (5) Replacing missing, altered, inactive, or dysfunctional genes will prevent diseases or even death. Also, progression of a disease can be monitored, and