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The history of medicine essay
Penicillin introduction
Letters about penicillin
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Nowadays, we are so indolent that we take for granted the medicine provided for us to cure our pain or illnesses and must feel privileged. When we date back to the 1800-1900, we will come to know that it wasn’t unusual for people to die with minor diseases, as there were no medicines invented for that certain type of disease. For decades, scientist and doctors worldwide have worked day and night in order to invent respective medicines and drugs that can help humankind to get rid of certain disease. Many drugs and medicines have been discovered or invented till today, but the medicine which has provided tremendous advantages to human kind due to its vast effectiveness is no other than Penicillin. Back in the medieval days, hospitals were full of people with infections and there wasn’t much to do but wait and hope. The Circumstances then were unsanitary and penicillin was unheeded.
Penicillin basically refers to any group of substances that are chemically similar and are obtained from molds of the Genus Penicillin. Penicillin was the first medicine discovered that successfully treated the bacterial infections caused by bacteria belonging to the genus of staphylococci. In the beginning, small amounts of penicillin were obtained from strains of mold P. Notatum.
There are seven main classes of antibiotics. One of the main classes is the penicillin group. Including penicillin, ampicillin, amoxicillin, and many others that end with cillin. This group’s main role is to fight bacteria that cause staphylococci etc.
We are auspicious to be provided with numerous amounts of different antibiotics for our medical conditions. Penicillin has been one of the consummate and powerful Medicines yet conceived, and an example of one such disco...
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...uperior amounts, but no attention was paid.
Later in 1938, 10 years after Fleming’s invention three scientists Howard Florey, Ernst Chain and Norman Heatley had prolonged Alexander Fleming’s work at the university of Oxford. They performed certain experiments for growing, sanitizing and extracting penicillin to substantiate its value as a drug. Norman Heatley, had recommended transferring the ingredient of penicillin back to water to change its acidity. By 1940 they produced adequate amount of penicillin to test on animals, which they tested on mice by injecting them with penicillin and streptococci to see which mice had survived. From the results they had gained, the mice that were injected with penicillin had survived whilst the other failed During the year 1942, a patient was successfully treated for the bacterial infections that he had by using penicillin.
This was a factor that was based on chance, as the penicillin (mould) had probably blown through a window. In my opinion Fleming didn't have much do to with the development of Penicillin, but he did recognise its importance and published his findings. Florey and Chain were scientists. They stumbled across Fleming's research papers and were intrigued by his findings. They were sure that, if Fleming was right, this discovery could save a lot of lives, prevent pain and make it much easier to fight infectious diseases and prevent other infections.
Medicine has been developed and discovered for thousands of years; however, the 1920’s was the first decade that fashioned a pathway for new developments and discoveries. Medical professionals have taken a huge hit for their fight in finding new inventions that can save patients from death’s hands. In the 1920’s, medicine has also taken a tremendous leap in controlling fatal diseases such as diabetes (Pendergast 110). Medicine in the 1920’s has altered the way medicine is shaped today; furthermore, the development and discovery of the iron lung, penicillin, and insulin were the first pertinent breakthroughs in medical history (“Iron” par. 7; Grimsley par. 15; “Banting” par. 13).
Penicillin, derived from the mold Penicillium, is the first antibiotic to successfully treat bacterial infections on humans. It was accidentally discovered by scientist, Alexander Fleming. While Fleming was growing Staphylococcus, a serious and often deadly infection, in a dish, he noticed the bacteria had stopped growing after a mold found its way
Today, Johnson & Johnson is a pharmaceutical giant worth $71 billion. The company is listed on NYSE as JNJ with 2.83 billion shares outstanding with the value of $92.7 per share.
The contributions of several doctors, researchers, and scientists helped improve the health of the growing population. In 1850 the average life expectancy was 42 years. By 1910 the average life expectancy had risen to nearly 55 years. Between 1850 and 1910 there were several advances in the medical field. The introduction of genes, white blood cells, blood groups, insulin, rubber gloves, aspirin, and vitamins and the discoveries of Pasteur, Charcot, Halsted, Zirm, Lister, and Koch were the starting point of an international fight against disease.
In the last decade, the number of prescriptions for antibiotics has increases. Even though, antibiotics are helpful, an excess amount of antibiotics can be dangerous. Quite often antibiotics are wrongly prescribed to cure viruses when they are meant to target bacteria. Antibiotics are a type of medicine that is prone to kill microorganisms, or bacteria. By examining the PBS documentary Hunting the Nightmare Bacteria and the article “U.S. government taps GlaxoSmithKline for New Antibiotics” by Ben Hirschler as well as a few other articles can help depict the problem that is of doctors prescribing antibiotics wrongly or excessively, which can led to becoming harmful to the body.
Medical procedures and inventions are constantly being developed and made better. World War 1 was a time in which many of the procedures used today were first thought of and used. It was a time that inspired the doctors and nurses working today, not to mention the fact that it’s a topic that still affects everyone in the world today. Medical advancements made during World War 1 had a major impact on the world as evidenced by those advancements still in use today.
Years later other scientists were also intrigued by the possibilities of penicillin and produced enough penicillin to prove that it was a useable antibiotic. The scientists from Great Britain were developing all of this during World War II, and unfortunately funding for their drug was unavailable due to the war. They decided to bring their concepts to the United States, and once enough was made, it was eventually used, to treat wounded soldiers during World War I.
The improvement of medicine over the course of the human successes gave great convenience to the people of today. Science has cured and prevented many illnesses from occurring and is on its way to cure some of the most dreadful and harmful illnesses. As the world modernizes due to the industrialization, so does the ways of medicine. Some cures are approached by chance, some, through intense, scientific measures.
18). Even though those diseases were not his goal to cure it still made penicillin revolutionary for the time being. Fleming now knew how to make penicillin and started to mass produce it. In the 1930s during the upgrading process of penicillin Fleming himself was cured of severe conjunctivitis. Then in the 1940s the fully developed penicillin was created. The creation of penicillin cured a wide variety of diseases, which led to the world excelling in growth, and penicillin improved the way of medicine at the time. The variety of diseases cured by penicillin made it a must have antibiotic. Penicillin was used to cure multiple diseases including syphilis, gonorrhea, tuberculosis, gangrene, pneumonia, diphtheria, and scarlet fever ( Common Antibiotics ). All the diseases have one thing in common, they all have the ability to spread, some faster than others. When a disease is discovered people tried to make a cure. When penicillin was made diseases that were thought to never have a cure were cured. People began to demand that penicillin be sold in local pharmacies. Penicillin was released to help people with the variety of diseases curable by
Compounding all of these solutions, the pharmaceutical industry needs to conduct extensive research on developing new antibiotics for various pathogenic bacteria by studying the bacterial structure. This will help scientists to formulate ways of counteracting the functions of the various constituents of bacteria.
Since antibiotics, such as penicillin, became widely available in the 1940s, they have been called miracle drugs. They have been able to eliminate bacteria without significantly harming the other cells of the host. Now with each passing year, bacteria that are immune to antibiotics have become more and more common. This turn of events presents us with an alarming problem. Strains of bacteria that are resistant to all prescribed antibiotics are beginning to appear. As a result, diseases such as tuberculosis and penicillin-resistant gonorrhea are reemerging on a worldwide scale (1).
Thesis: With the advent of antibiotics in 1929 Fleming said, "The time may come when penicillin can be bought by anyone in the shops.Then there is the danger that the ignorant man may easily underdose himself and by exposing his microbes to non-lethal quantities of the drug make them resistant."With the overuse of antibiotics today we have seen this very idea come to be.Over usage is caused most prevalently by a lack of education on the part of the patient.Thus stated, the way to overcome such a circumstance is to educate, not only the patient but also the physician.
Discovery and Development of Penicillin. (2014, April 4). Retrieved from American Chemical Society International Historic Chemical Landmarks: https://www.acs.org/content/acs/en/education/whatischemistry/landmarks/flemingpenicillin.html
The discovery of antibiotics is attributed to Alexander Fleming who discovered the first antibiotic to be commercially used (Penicillin) in approximately 1928. An antibiotic, also known as an antimicrobial, is a medication that is taken in order to either destroy or slow the growth rate of bacteria. Antibiotics are integral to the success of many medical practises, such as; surgical procedures, organ transplants, the treatment of cancer and the treatment of the critically ill. (Ramanan Laxminarayan, 2013)