Swine Flu Research Paper
Swine flu is a disease that has placed a burden on humanity for many years. The virus of swine flu has a very intriguing history as well. Swine flu had originated from the first influenza pandemic in 1918. The actual swine flu virus had come from a pig in Iowa in 1931. Two years later a human strand of swine flu was found in London for the very first time. This was later followed by the Hong Kong flu pandemic in 1968 which had killed up to one million people worldwide. Many years after these pandemics had occurred, the first cases of swine flu were found in California and Texas in March of 2009. This pandemic killed 25,174 people who were infected with swine flu. A couple of months later, the United States and the United Kingdom began testing people for the swine flu and started vaccination programs. Swine flu has had a long history and has taken a large number of lives in the past with worldwide pandemics. As a result, countries like the United States started to take measures toward vaccination. The virus has many different ways of being transmitted, signs and symptoms, areas of the world it infects, and treatment plans.
The size of the swine flu virus ranges anywhere from ten to three hundred nanometers in diameter. In comparison to real world measurements, one nanometer is one one-millionth of a millimeter. The shape overall is a sphere which means it targets members of the animal kingdom like mammals. The swine flu virus is not categorized in a kingdom, phylum, or class because it is not considered to be living. However, it is part of the order of mononegavirales which includes all viruses that can infect any of the six kingdoms. The family is orthomyxoviridae which is all spheri...
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...influenza pandemic in one way or another; the use of quarantines were extremely prevalent among them. Also, the pandemic is directly responsible for the creation of many health organizations across the globe. The organizations help track and research illnesses across the globe. The CDC (Centers for Disease Control and Prevention) for example, strive to prevent epidemics and pandemics. They also provide a governing body with directives to follow in case an outbreak does occur, and if one shall occur the efforts of organizations across the globe will be crucial for its containment. It is amazing that with modern medicine and proper organization that influenza still manages to make its appearance across the globe annually.
However due to globalization, import and export viruses is more easily transmitted. Over the past century the global community especially Asian has been affected with new strains of the influenza virus. The changes in the virus can occur in two ways “antigenic drift” which are gradual changes in the virus over time. This change produces new strains that the antibody may not recognize. “Antigenic shift” On the other is a sudden change in the influenza virus which ‘’ results in a new influenza A subtype or a virus with a hemagglutinin or a hemagglutinin and neuraminidase combination that has emerged from an animal population,” as seen with H5N1 virus. This change leaves people defenseless against this new virus. (CDC, 2013) Currently there is no vaccine to combat all strains therefore “Planning and preparedness for implementing mitigation strategies during a pandemic requires participation by all levels o...
The influenza or flu pandemic of 1918 to 1919, the deadliest in modern history, infected an estimated 500 million people worldwide–about one-third of the planet’s population at the time–and estimates place the number of victims anywhere from 25 to 100 million. More than 25 percent of the U.S. population became sick, and some 675,000 Americans died during the pandemic. The 1918 flu was first observed in Europe, the U.S. and parts of Asia before swiftly spreading around the world. Surprisingly, many flu victims were young, otherwise healthy adults. At the time, there were no effective drugs or vaccines to treat this killer flu strain or prevent its spread. In the U.S., citizens were ordered to wear masks, and schools, theaters and other public
A few years before 1918, in the height of the First World War, a calamity occurred that stripped the globe of at least 50 million lives. (Taubenberger, 1918) This calamity was not the death toll of the war; albeit, some individuals may argue the globalization associated with the First World War perpetuated the persistence of this calamity. This calamity was referred to the Spanish Flu of 1918, but calling this devastating pestilence the “Spanish Flu” may be a historical inaccuracy, as research and historians suggest that the likelihood of this disease originating in Spain seams greatly improbable. Despite it’s misnomer, the Spanish Flu, or its virus name H1N1, still swept across the globe passing from human to human by exhaled drops of water that contained a deadly strand of RNA wrapped with a protein casing. Individuals who were unfortunate enough to come in contact with the contents of the protein casing generally developed severe respiratory inflammation, as the Immune system’s own response towards the infected lung cells would destroy much of the lungs, thus causing the lungs to flood with fluids. Due to this flooding, pneumonia was a common cause of death for those infected with Spanish Flu. Due its genetic similarity with Avian Flu, the Spanish Flu is thought to be descended from Avian Flu which is commonly known as “Bird Flu.” (Billings,1997) The Spanish Flu of 1918 has had a larger impact in terms of global significance than any other disease has had because it was the most deadly, easily transmitted across the entire globe, and occurred in an ideal time period for a disease to happen.
"Pandemic Flu History." Home. U.S. Department of Health & Human Services, n.d. Web. 23 Mar.
The virus is primarily spherical shaped and roughly 200nm in size, surrounded by a host-cell derived membrane. Its genome is minus-sense single-stranded RNA 16-18 kb in length. It contains matrix protein inside the envelope, hemagglutinin and neuraminidase, fusion protein, nucleocapsid protein, and L and P proteins to form the RNA polymerase. The host-cell receptors on the outside are hemagglutinin and neuraminidase. The virus is allowed to enter the cell when the hemagglutinin/ neuraminidase glycoproteins fuse with the sialic acid on the surface of the host cell, and the capsid enters the cytoplasm. The infected cells express the fusion protein from the virus, and this links the host cells together to create syncitia.
One of the most virulent strains of influenza in history ravaged the world and decimated the populations around the world. Present during World War I, the 1918 strain of pandemic influenza found many opportunities to spread through the war. At the time, science wasn’t advanced enough to study the virus, much less find a cure; medical personnel were helpless when it came to fighting the disease, and so the flu went on to infect millions and kill at a rate 25 times higher than the standard.
The influenza pandemic of 1918-1919 killed more people than the Great War, known today as World War I (WWI), at somewhere between twenty and forty million people. (1) Influenza is a virus that appeared in 1918 and caused a pandemic. It made an enormous impact that is still significant to the world today. It has pushed scientists to make advancements in the medicine and vaccination industry that continue to grow each and every day. Influenza may be a horrible thing, but without it we wouldn’t be where we are today.
“Selecting the Viruses in the Seasonal Influenza (Flu) Vaccine.” Centers for Disease Control and Prevention. USA.gov, 9 March 2011. Web. 19 Jan. 2010
Hvistendahl, M, Cohen, J et. al. 2013. ‘New Flu Virus in China Worries and Confuses’ Science 340: 129-130
In order to decide whether or not the swine flu vaccine is completely necessary, one must first gain a better understanding of the topic. It is a scientifically known fact that the swine flu is a result of a virus. A virus is a capsule of genetic material that causes infection in the body. The infectious particles are made up of nucleic acid enclosed in a protein shell, called a capsid. It cannot be considered a living organism like the disease causing agent of bacteria, because it does not carry out all the characteristics of life. Specifically, it cannot reproduce on its own.
Description Influenza, commonly known as the flu, is a highly contagious disease (caused by influenza viruses of varying forms) that has been around for more than 2,500 years. There are three main types of the virus; types A, B and C. Once the minuscule particles of the virus are inhaled, they locate their target cells using the proteins that surround the nucleus. These contain genetic material, which then trigger the target cells to produce more virus particles. Once these cells spread through the body and into the immune system, an infected person will begin to feel the physical symptoms of the flu.
A common strain of the flu, H-3-N-2, has led to an epidemic across the country. The strain is becoming known as quick killer. While people still have the usual symptoms chills, fever, muscle pain, headache, dry cough, high temperature and loss of appetite. 1 Millions are becoming increasingly concerned about the risk of their health. ABC new tonight with David Muir reported on Tuesday January 16, 2018 of the recent death of a mother from San Jose, California. Katie Thomas was a mother of three and known to be joyful, vibrant, and even an active participant in marathons. However unlike the normal masses of people who catch the flu during the winter season, she unfortunately didn’t not recover from her illness. 48 hours after being diagnosed with the flu, the mother died from the influenza. This came as to a shock to her family and friends due to her being such a healthy person. Sadly this case was not the first one of the season. Last week a 4 year old, Jonah Reiben, also
The word influenza originated from Italy people thought that the planet, stars, and moon caused the flu; they believed that powerful forces created unexpected sickness. The flu is contagious and effects breathing primarily infecting the nose, throat, and lungs. The flu varies in the degree of severity and at worst can lead to death. The flu is transmitted through the air via droplets, people spread through talking, sneezing and coughing. The Flu can be through touching an infected area such as door handles, keyboards, or cell phones. Also another way to transmit the disease is through birds or deceased birds infected with the virus. There are 3 different types of flu viruses A, B or C. A is more infections then B. C is associated with H3N2 and B with H1N1. There is another version of the flu called the avian influenza, which comes from birds usually spread through deceased birds or excrement. The Flu viruses are evolving if you had the flu in the past or had immunization your body has built immunity to that particular strain but you can still infected. In most cases the flu you had before can’t prevent you from the new viruses.
The swine influenza or swine flu is a respiratory disease in pigs that is caused by the type A influenza viruses. These viruses are referred to as swine flu viruses but scientifically the main virus is called the swine triple reassortant (tr) H1N1 influenza virus. When the viruses infect humans they are called variant viruses. This infection has been caused in humans mainly by the H1N1v virus in the United States. The H1N1 virus originates in animals due to improper conditions and the food they ingest. The virus stays in latency form, thus harmless to the respective animal. The longer the animals survive the more likely the virus is to develop and strengthen making it immune to vaccines. The virus reproduced through the lytic cycle. The virus injects its own nucleic acids into a host cell and then they form a circle in the center of the cell. Rather than copying its own nucleic acids, the cell will copy the viral acids. The copies of viral acids then organize themselves as viruses inside of the cell. The membrane will eventually split leaving the viruses free to infect other cells.