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Common differential diagnosis
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What is your differential and presumptive diagnosis at this point? Describe the thought process that selects one of these diagnoses over the other.
Differential Diagnosis: Bronchiolitis, viral Pneumonia, Bacterial Pneumonia, Influenza, Foreign Body
My Presumptive diagnosis given this information is RSV bronchiolitis. The rationale behind this is that it is a common pediatric illness that causes difficulty breathing and a cough. Other clues to this diagnosis include the onset of the disease which was gradually worsening and a low grade fever. Additionally, on physical exam the presence of dull tympanic membranes suggests there is possible otitis media, which is common in children who have bronchiolitis. Due to the nature of the onset and presenting
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This virus gets into the epithelium of the bronchioles cells. Once inside of the cell, the virus begins to replicate and spread through the airway. At the same time monocytes and macrophages that are inside of the airways phagocytize the virus and present them on their membrane. This causes an immunologic response that leads to the release of inflammatory mediators. The purpose of these inflammatory mediators is to recruit more cells into the lung tissue to fight off the infection. The more mediators that are drawn into the periphery the greater the pulmonary symptoms will be. The reason for this is because the symptoms are actually a response to the obstruction that the inflammatory mediators and white blood cells cause. This is significant because the bronchioles are very narrow tubes about 2mm in diameter and can be easily obstructed blocking the exchange of oxygen, which produces the high respiratory rate, low oxygen saturation, and wheezes that are heard on physical …show more content…
Which means instead of opening up the airways it actually causes them to constrict. It is also possible that the introduction of a Beta-2 agonist increased the V/Q mismatch even more because there is an increase blood flow that needs to be perfused. Unfortunately, the obstruction in bronchioles prevents in proper perfusion, because it remains intact and still blocking the airway despite dilation. This results in the body trying to compensate which is why the patients respiratory rate went up and began to show signs of distress.
What are the current practice guidelines for using albuterol for this condition?
Currently there are no recommendations for the use of bronchodilators. There is no evidence to support that the use of this medication actually relieves the symptoms or decreases of the course of the disease. The reason this is so is because bronchiolitis is a disease that is caused by an obstruction in the airway and not a result of the constriction.
Why is the information about the pregnancy important?
The reason the information about the pregnancy is important is because it is helpful and determining how severe the disease could actually. A premature birth increases the severity usually 32 weeks or early is a sign that this infection could require hospitalization. Other birth history that is important is knowing if he has a congenital heart defect or a low birth weight. Which would
Ransley reports frequent nasal congestion that has been more problematic in the last couple of weeks and I note you have commenced him on some oral antibiotics and prednisolone which seems to be helping.
Racemic albuterol is a β2- adrenergic agonist that is a 50:50 mixture of two isomers, (R) albuterol and (S) albuterol. These two isomers are mirror images of each other, and rotate light in opposite directions. (R) Albuterol is an active isomer and in this combination acts an active bronchodilator. The other half of the mixture, (S) albuterol, does not actually possess any bronchodilator activity and was until recently considered an “inactive” distomer or physiologically inert. The “R” stands for rectus or right, while the “S” is for sinister or left. Racemic albuterol was synthesized for maximal airway smooth muscle dilation while minimizing the α- and β1-receptor mediated effects on the cardiovascular system.
Also contributing to the virulence of the bacteria are the exotoxins including invasive adenylate cyclase, tracheal cytotoxin, and lethal toxin. Invasive adenylate cyclase reduces local phagocytic activity as well as acting as a hemolysin. Tracheal toxin affects the ciliated respiratory epithelium by inhibiting the ciliary beating. This kills the cells and causes them to be eliminated from the mucosa. Tracheal toxin also stimulates the release of IL-1, which causes fever. Lastly, lethal toxin causes inflammation and local necrosis at infection sites.
Croup: Croup is another common airway inflammation caused by virus that can affect the trachea, larynx and possibility the bronchi (Murray, Sidani, & Zoorob, 2011) thus causing infection in the upper respiratory tract. Murray et al. describes it as the most common illness in children under the age of 6 to 36 months and cause for cough mostly when a child cries; acute stridor and hoarseness in febrile children (Murray et al., 2011). It can be a life-threatening situation in the life of the young infant and the family. Croup symptoms exhibit as hoarseness, barking cough, inspiratory stridor, and respiratory distress. I chose this diagnosis as my first preference because when I read the mother’s subjective report it matches that of croup symptoms: a barking cough, no fever, severe at night and when the baby cries, fatigue due to excessiveness of the tears, pain due to inflames and swollen of the airway. Murray et al., led us to understand that the etiologies of this viral causing agent can be traced to the parainfluenza viruses, type 1. (2011). This virus is commonly spread through contact or droplet secretion.
Oxygen, inhaled bronchodilators, inhaled steroids, combination inhalers, oral steroids, phosphodiesterase-4 inhibitors and theophylline are effective medications for COPD (Mayo Clinic, 2016). “Patients with COPD have persistent high levels of CO2, their respiratory centers no longer respond to increased levels of CO2 by stimulating breathing. Therefore, COPD patients with more severe hypoxemia are at higher risk of CO2 retention from uncontrolled CO2 administration” (Van Houten, p. 13). For nurses, “It is important to administer the lowest amount of O2 necessary to patients” (Van Houten, p. 13). Some COPD medicines are used with inhaler and nebulizer devices. It is important to teach patients how to use these devices correctly. (Potter & Perry,
...a are bronchodilators like anticholinergic, beta agonists, theophylline and oxygen, which are for the advance cases of the disease. In addition, the best treatment for people whom have emphysema is for them to stop smoking.
The second intervention to improve gas exchange related to ineffective airway clearance is the use of a positive expiratory pressure device (PEP). PEP devices work by providing constant backwards pressure on the airways during expiration.
Person, A. & Mintz, M., (2006), Anatomy and Physiology of the Respiratory Tract, Disorders of the Respiratory Tract, pp. 11-17, New Jersey: Human Press Inc.
Federman DG, Chanko EH. Differential Diagnosis in Internal Medicine: From Symptom to Diagnosis. JAMA.2007;298(17):2070-2075. doi:10.1001/jama.298.17.2072.
The clinical manifestation one may see in patients with chronic bronchitis are chronic cough, weight loss, excessive sputum, and dyspnea. Chronic cough is from the body trying to expel the excessive mucus build up to return breathing back to normal. Dyspnea is from the thickening of the bronchial walls causing constriction, thereby altering the breathing pattern. This causes the body to use other surrounding muscles to help with breathing which can be exhausting. These patients ca...
His positive result of nasopharyngeal aspirate for Respiratory Syncytial Virus (RSV) indicates that Liam has acute bronchiolitis, which is a viral infection (Glasper & Richardson, 2010). “Bronchiolitis is the most common reason for admission to hospital in the first 6 months of life. It describes a clinical syndrome of cough tachypnoea, feeding difficulties and respiratory crackles in chest auscultation” (Fitzgerald, 2011, p.160). Bronchiolitis can cause respiratory distress and desaturation (91% in the room air) due to airway blockage; therefore the infant appears to have nasal flaring, intercostal and subcostal retractions, and tachypnoea (54 breathes/min) during breathing (Glasper & Richardson, 2010). Tachycardia (152 beats/min) could occur due to hypoxemia and compensatory mechanism for low blood pressure (74/46mmHg) (Fitzgerald, 2011; Glasper & Richardson, 2010).
The virus attacks the lymph nodes and lungs. The buboes formed from the virus are usually formed in the groin or armpit depending on the closest lymph node. The plague is highly contagious, spread by speaking, coughing, and sneezing. There are two types of plague, the septimic and the pneumonic.
... is called Ventolin Inhalers, also known as Albuterol Inhalers. Approximately 90% of the fast-acting inhalers contain a medicine called albuterol. Albuterol Inhalers relieve bronchospasm. (An abnormal contraction of the smooth muscle of the bronchi resulting in an acute narrowing and obstruction of the respiratory airway.) The medicine will quickly open up the airways in the lungs so breathing will be more easily.
A 41-year-old manwith a history of DM was brought to emergency department (ED)due to difficulty in breathing. It was associated with fever, severe sore throat and muffled voice for 2 days duration. He visited a...
#1 If you haven’t yet been diagnosed you may experience any of the following :