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An essay on ethical research
An essay on ethical research
Thesis on medical ethics
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What exactly is ethical behavior when it comes to human experimentation? Nowadays, people would claim it has to be honest, fair, safe, and humane. However, that criteria had not prevailed through all of history. Early on, scientists often used questionable techniques to obtain research because ethics would not be an important issue until well into the 20th century. In her book, The Immortal Life of Henrietta Lacks, Rebecca Skloot uses tone and diction to illustrate the historical evolution of the ethics surrounding human experimentation.
In the 19th and 20th centuries, researchers did not consider ethics when using minorities in research. For example, doctors tested drugs and new surgical techniques on slaves. The doctors did not even use
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anesthesia, let alone ask for permission. Also, in the early 1900s, researchers exhumed black corpses for experimentation without familial consent. Northern schools bought black bodies for anatomy courses through an underground shipping industry. Back then, these actions were considered fine because people were more concerned with discovery rather than ethics. Ethics would not be an issue for decades to come. Rebecca Skloot presents these details in a reportorial, unbiased tone. She says the “corpses were routinely exhumed from graves,” not showing any resentment or even support towards the doctors. Had she wanted to have a more angry and passionate tone, she could have used different diction, like “carcasses were unjustly ripped from tombs.” Skloot is not trying to push her agenda so readers can better evaluate the information she’s presenting and make a decision for themselves. By the 1930s, not much debate had been stirred about unethical experimentation of minorities.
Starting from that decade, the U.S. Public Health Service researchers at the Tuskegee Institute recruited black men with syphilis to study how their disease killed people. The researchers watched each man die, even after realizing penicillin could cure him. They chose black subjects specifically because they, along with many other white people, believed black people were “notoriously syphilis-soaked.” The researchers, and the public at the time, did not care about the deaths of a so-called racially inferior group. All the scientists gave to the families of those who died was a fifty-dollar stipend. Here Rebecca Skloot’s tone is more indignant. She chooses to describe the black men’s deaths as slow, painful, and preventable. She is clearly upset at the researchers’ flippant carelessness with black lives and wants the reader to understand the injustice of their actions. Also in the 1930s, in what was called the Mississippi Appendectomies, hysterectomies were performed involuntarily on poor black women. Doctors wanted to practice and to sterilize the women. Again, Skloot’s tone is upset. She uses the word choice of “unnecessary” to enforce that the doctors were not even trying to treat the women. The reason her tone might have been more passionate was because these experiments were part of a conversation she had with Roland Pattillo. She wanted to impress him so he would put her in touch with the Lacks family. A more emotional response was needed to show how much she cared about the wrongdoings black people
endured. In the 1950s, the discussion of ethics still had not risen. During this era, patients going to public wards would unknowingly be used in research. Doctors believed that since they received free treatment, taking part in experiments would be their payment. In 1954, Chester M. Southam injected about a dozen cancer patients with HeLa, which were malignant cells. Tumors began to grow on the injection site for all the patients. In one, the HeLa cells even metastasized to her lymph nodes. Southam only told them that he was testing their immune system. Two years later, he performed the same experiment on prisoners. This time, he told the subject they were there for cancer research, but did not explain further or attempt to gain informed consent. Also in the 1950s, Crownsville State Hospital, formerly known as the Hospital for the Negro Insane, conducted research on patients without consent. For example, the staff performed pneumoencephalographies without permission from the patient or the parents. Pneumoencephalography was a technique for taking images of the brain. Doctors drilled holes into subjects’ skulls, drained their brain fluid, and pumped air or helium in instead. This allowed for crisper X-rays. The doctors did not even question if what they were doing was moral. Skloot’s tone is once again formal and explanatory. The neutrality of her tone helps her purpose of educating others about the ethics of human experimentation. She doesn’t want to force readers to feel the same as her; she just wants them to understand and learn. Finally in the 1960s, ethics started to become a debate. In 1963, Chester Southam and Emanuel Mandel, director of medicine at the Jewish Chronic Disease Hospital, teamed up to use the hospital’s patients for research. Mandel instructed his staff to give injections containing cancer to patients without their knowledge or consent. Three young Jewish doctors refused because they all knew about the nonconsensual research Nazis did on Jews and other concentration camp prisoners. This research was brought to light through the Nuremburg Trials. In 1947, seven Nazi doctors were sentenced to death by hanging for their experiments. They sewed siblings together and dissected living people. A code of ethics, now known as the Nuremburg Code, was set forth. However, it was never taught in medical schools. Here Skloot’s diction does give away her voice. She described the research as unthinkable and she said Southam “claimed” not to know the Nuremburg code existed. Claimed has a connotation of deception. It shows Southam clearly knew what he was doing, but was playing innocent. Skloot could have used “said” since it has a more neutral implication, but she chose “claimed.” Perhaps this stray from her usual tone is a reflection of her own half-Jewish heritage. In the 1970s and 1980s, ethics became more of an issue. In the 1970s, prisoner experimentation came under heavy scrutiny and started being regulated. Moreover, during that decade the public finally learned about the Tuskegee syphilis studies. The media went crazy. Rumors starting spreading that doctors injected the men with syphilis. People were finally paying attention. Ethics about human experimentation have changed over time. They came all the way from routinely using slaves as research subjects to injections, sterilizations, and surgeries on unknowing patients to people finally taking a stand. Rebecca Skloot used mostly an unbiased tone to demonstrate this evolution. Now how will ethics transform in the future and what current injustices will eventually be realized and scrutinized?
The Immortal Life of Henrietta Lacks by: Rebecca Skloot has a lot of themes, but one that is most relevant in my opinion is the racial politics of medicine. Throughout the chapters, there were examples of how Henrietta, being African American, prevented her from receiving the same treatment as the white woman sitting right next to her in the waiting room. The story begins with Henrietta going to Johns Hopkins Hospital and asking a physician to check a “knot on her womb.” Skloot describes that Henrietta had been having pain around that area for about a year, and talked about it with her family, but did not do anything until the pains got intolerable. The doctor near her house had checked if she had syphilis, but it came back negative, and he recommended her to go to John Hopkins, a known university hospital that was the only hospital in the area that would treat African American patients during the era of Jim Crow. It was a long commute, but they had no choice. Patient records detail some of her prior history and provide readers with background knowledge: Henrietta was one of ten siblings, having six or seven years of schooling, five children of her own, and a past of declining medical treatments. The odd thing was that she did not follow up on upcoming clinic visits. The tests discovered a purple lump on the cervix about the size of a nickel. Dr. Howard Jones took a sample around the tissue and sent it to the laboratory.
According to the Belmont Report (1979), justice is relevant to the selection of subjects of research at two levels: the social and the individual. Skloot (2010) describes how “Gey took any cells he could get his hands on” and how “TeLinde began collecting samples from any woman who walked into Hopkins with cervical cancer” (p. 30). These two doctors did not exhibit fairness in their selection of subjects. Dr. TeLinde was collecting samples from women on the color ward and did not consider the appropriateness of placing further burdens on already burdened persons. The women whose tissue samples are being gathered for research are the women who will most likely be the last to benefit; because more advantaged populations (wealthy and white) will initially be the primary
Rebecca Skloot’s novel, The Immortal Life of Henrietta Lacks, depicts the violation of medical ethics from the patient and researcher perspectives specifically when race, poverty, and lack of medical education are factors. The novel takes place in the southern United States in 1951. Henrietta Lacks is born in a poor rural town, Clover, but eventually moves to urban Turner Station. She was diagnosed and treated for cervical cancer at Johns Hopkins hospital where cells was unknowingly taken from her and used for scientific research. Rebecca Skloot describes this when she writes, “But first—though no one had told Henrietta that TeLinde was collecting sample or asked she wanted to be a donor—Wharton picked up a sharp knife and shaved two dime-sized pieces of tissue from Henrietta's cervix: one from her tumor, and one from the healthy cervical tissue nearby. Then he placed the samples in a glass dish” (33). The simple act of taking cells, which the physicians did not even think twice about, caused decades
Ethical violations committed on underprivileged populations first surfaced close to 50 years ago with the discovery of the Tuskegee project. The location, a small rural town in Arkansas, and the population, consisting of black males with syphilis, would become a startling example of research gone wrong. The participants of the study were denied the available treatment in order further the goal of the research, a clear violation of the Belmont Report principle of beneficence. This same problem faces researchers today who looking for an intervention in the vertical transmission of HIV in Africa, as there is an effective protocol in industrialized nations, yet they chose to use a placebo-contro...
The Deadly Deception video scrutinizes the unjust practices of a syphilis study that began in the 1930’s on the campus of Tuskegee Institute by the U.S. Public Health Service. The experiment was conducted using hundreds of African American men that were mainly poor and illiterate. The study was called the Tuskegee Study of Untreated Syphilis in the Negro Male. Participates were deceived and lured in by promises of free medical care and survivors insurance.
The Tuskegee study of untreated syphilis in the Negro Male population was studied to improve the health of poor African Americans. Men were recruited for this study and were promised free medical examinations, blood tests, and medicines. Bessie disliked going to the doctor, however, she would really not really seek health care knowing the circumstances of this case. Trusting the health care providers would be her biggest issue. Not being able to communicate and understand a patient, as a caregiver would make me not want to go to the doctor as well. Annette Dula would suggest that the need for dialogue with African Americans should be recognized as a serious bioethical problem. I would suggest that health care providers should know different dialogue to get a better understanding of their patients. I agree with the three health disparities: institutional racism, economic equality, and attitudinal barriers to
"Nazi Medical Experimentation: The Ethics Of Using Medical Data From Nazi Experiments." The Ethics Of Using Medical Data From Nazi Experiments. N.p., n.d. Web. 09 Dec. 2013.
Does racism still exist today? Although many believe it was a problem in the past, it still exists today. Many People are still not aware that it still exists in our workforces, especially in medical field. Although racism in medicine can be very offense, it can sometimes be beneficial and help reveal differences in diseases based on genetic make up. These differences can be taken in the wrong manner and can lead to social problems especially if these distinctions are thought of as ethnic differences. In Gregg M. Bloche’s article. “Race, Money and Medicine”, he states that we should erase racial categories from medicine but only use them if they are beneficial for the patient’s health. Peter Clark, author of “Prejudice and the Medical Profession: A Five Year Update”, explains that racial categories should be understood because understand these different can be beneficial. Lynne D. Richardson and Marlaina Norris, authors of “Access to Health and Health Care: How Race and Ethnicity Matter”, also believe that these differences can be beneficial but want to improve the health are because they know a majority of minorities do not receive proper health care and treatment. Rebecca Skloot, author of “The Immortal Life of Henrietta Lacks”, pays attention to the fact that her character, Henrietta Lacks, was not given the proper treatment and care she should have. Although Henrietta’s cells were beneficial to cancer research , she never once gave consent to the doctor’s to distribute her cells. She was taken advantage of because of her race and low income. Minorities’ opinions and beliefs should be taken into perspective because they often feel neglected which causes a sense of “distrust”. There has been a vast history of racism in the ...
Miss. Evers Boys is a movie based on the real life study called “The Tuskegee Study” that took place in Macon County, Alabama, where 400 black men who had syphilis and 200 black men without this disease participated on this study without knowing the terrible truth behind it. Also the participants were poor and uneducated sharecropper who fell for Miss. Evers persuasions and rewards that doctors were offering to participants. The main results that doctors were trying to obtain from this experiment was to gain information about how African Americans men’s bodies reacted to syphilis. During the 1930’s, society believed that black men were inferior to white men, so diseases were supposed to affect differently black men. This study in particular, the participants were not informed about the capacity that this disease could damage their human system and they were not viewed as a human being and they were used as lab rat. Furthermore, one of the doctors who were involved in this experiment Dr. Raymond Vonderlehr used the term “necropsy” that is an autopsy performed on animals when speaking about the participants of this experiment (Mananda R-G, 2012).
Ethics of Medical Research with Animals,. 'U.S. Law And Animal Experimentation: A Critical Primer - Ethics Of Medical Research With Animals'. N. p., 2014. Web. 6 May. 2014.
Wepworth, Adam. "Animal Research: The Ethics of Animal Experimentation." (n.d.): n. pag. 16 July 2010. Web. 12 Nov. 2013.
Knowing the rudimentary explanation of morality, ethics could almost be described as the law of morality. The word ethics is used in an abundance of contexts and therefore is described using a vast amount of different guidelines. When biomedical or behavioural research is conducted on humans, which almost is the only research conducted on humans, a specific set of laws known as ‘The Belmont Report’ demands adherence. Originating in the USA in 1979 it is now used almost worldwide, while it is a short set of laws it explicitly states the benefits of the research must outweigh any risks to the participants, each participant must b...
Unethical experiments have occurred long before people considered it was wrong. The protagonist of the practice of human experimentation justify their views on the basis that such experiments yield results for the good of society that are unprocurable by other methods or means of study ( Vollmann 1448 ).The reasons for the experiments were to understand, prevent, and treat disease, and often there is not a substitute for a human subject. This is true for study of illnesses such as depression, delusional states that manifest themselves partly by altering human subjectivity, and impairing cognitive functioning. Concluding, some experiments have the tendency to destroy the lives of the humans that have been experimented on.
In the natural sciences there are always ethical norms that limit how knowledge can be produced. In the natural sciences, experimentation is an important method of producing knowledge but ethical judgments can limit the use of this method. There are areas that are considered unethical ...
It has long been debated as to whether it is ethical to use animals for experimentation. When considering whether animal research is ethically acceptable or not two main concerns must be raised. The first issue is whether it is absolutely necessary to use animals in order to acquire information that may contribute to the improvement of people’s health and well-being. The second issue is whether the use of animals is defendable on a moral ground.