Proteins: A Macromolecule In Blood

209 Words1 Page
bulb-icon

Recommended: Case studies on hemophilia

Proteins, a macromolecule in the blood, serve many functions. One of these is to assist in blood clotting. There are 13 proteins that make up the clotting cascade. After a bleeding episode or injury, the clotting cascade is activated. These proteins work together in the blood to create what is known as a fibrin clot. A fibrin clot is what most people know as a scab. This clot stops the loss of blood and keeps it circulating inside the veins to continue its mission of carrying oxygen and other vital things to our organ systems.
For someone with Hemophilia, a bleeding disorder, this process does not work as it should. In a person with Hemophilia, the eighth or ninth protein in the clotting cascade is either missing or at very low levels in the

Show More
Related

  • Pathophysiology of Sepsis Inflammatory Response

    987 Words  | 2 Pages

    In septic patients, increased levels of PAI-1 inhibit plasminogen activator (t-PA), which converts plasminogen to plasmin. Release of fibrin inhibits fibrinolysis by activation of thrombin-activatable fibrinolysis inhibitor (TAFI). In addition, the release of PAF causes platelet aggregation. This combination of inhibition of fibrinolysis, fibrin strand production and platelet aggregation contribute to a state of coagulopathy. This can lead to microcirculatory dysfunction with isolated or multiple organ dysfunction and cell death. Mr Hertz’s coagulation profile showed a fibrinogen level of 5.6 g/L, indicating that coagulopathies were underway in his system.

    Read More

  • hemophilia

    2023 Words  | 5 Pages

    Hemophilia is a genetic bleeding disorder. People who have hemophilia have a deficiency or an absence of a coagulation protein. A blood clotting factor is deficient or absent. Bleeding is most often in joints, such as the knee, elbow, or ankle, but bleeding can occur anywhere in the body. People with hemophilia bleed longer, not faster.

    Read More

  • Overview of The Cardiovascular System

    1664 Words  | 4 Pages

    Protection- The cardiovascular system protects the body through its white blood cells. Platelets and red blood cells form scabs to seal wounds and prevent pathogens from entering the body and liquids from leaking out.

    Read More

  • Myocardial Infarction Research Paper

    719 Words  | 2 Pages

    The next stage in myocardial infarction is the formation of thrombus. Exposure of the subendothelial matrix of the plaque to blood due to superficial abrasion generates platelet activation and aggregation. Clotting factors on the platelet membrane carry out reaction which release prothrombin activator, this activator then converts prothrombin to enzyme thrombin. The transformation of fibrinogen to fibrin is then catalysed by thrombin. During proteolysis (the breaks down of protein), fibrinogen is converted to fibrin strands which stabilize the final blood clot. Complete occlusion of coronary artery by thrombus disrupts blood flow and causes ischemia due to atherosclerotic coronary artery steno...

    Read More

  • Hemophilia Research Paper

    881 Words  | 2 Pages

    Hemophilia is a rare bleeding disorder that slows the blood clotting process, which is not normal. Some people with Hemophilia may just have a little bit of “clotting factor” or no clotting factor at all (National Institute of Health [NIH], 2013). Clotting factor is a protein in blood that controls bleeding and they are needed the blood to clot normally. In order to help the blood clot, clotting factors work with “platelets” (National Institute of Health [NIH], 2013). Platelets are small blood cell fragments that form in the bone marrow, a tissue in the bones that is similar to a sponge. The functions of platelets have a very important role in blood clotting; the role of a platelet is to stick together (by the help of clotting factors) to block cuts, break on the carriers of blood (veins or arteries) throughout the body, and stop the bleeding when “blood vessels” (National Institutes of Health [NIH], 2013) are injured. Blood vessels are tube like structures carrying blood through the tissues and organs, like a vein, artery, or capillary. People with hemophilia do not have enough “clotting factor VIII or IX” (World Federation of Hemophilia [WFH], 2013) in their blood, which results to prolonged bleeding or oozing, meaning that bleeding can last longer (though, not faster) than usual after surgeries, accidents, or having teeth pulled out at the dentist. Clotting factor VIII, which can also be called as “anti-hemophilic factor” (AHF, for short) (Patient.co.uk, 2011), is a blood clotting protein that is necessary for humans to have. Clotting Factor IX is a protein that i...

    Read More

  • Hemophilia Essay

    1255 Words  | 3 Pages

    Hemophilia is a genetic disorder in which the blood does not clot normally. It’s a rare bleeding disorder that has been happening since ancient times. Men are the ones mainly affected by it. One in five thousand men born each year have Hemophilia. Yet women can be carriers and just like men, they can suffer from symptoms too. Women can only have Hemophilia if their father does and mother is a carrier, it’s uncommon but can happen. Hemophilia affects all races and ethnic groups. It’s all based on your family tree. A man with Hemophilia will pass the gene down to his daughters, leading to them becoming carriers. A woman with the gene has a fifty percent chance of passing the gene down on to her sons. If there was no family history of Hemophilia but the woman is a carrier, a son could possibly be the first one in the family to have it. If there’s one thing for certain about hemophilia is that it does not discriminate against anyone. Hemophilia has affected royalty as well as high and low class men all throughout history.

    Read More

  • Informative Speech On Hemophilia

    591 Words  | 2 Pages

    Today i'm going to be talking about Hemophilia and the general overview of it. I will also talk about any potential cures. I will be talking about what Hempohilia can do to your body. I will also be talking about if theres a cure or just a treatment to make it less worse. I will also be talking about how people with Hemophilia deal with this disease. I will also explain how people will benefit from extended research on thi s topic. I’ll also talk about my personal opininon on this topic and what I think about it. So for my first question I’m explaining what the characteristics of Hemophilia are. The characteristics of Hemophilia are not very deadly but can be very annoying I’ll also explan the genetic causes of this disease.

    Read More

  • False Anxiety Essay

    1122 Words  | 3 Pages

    Whenever an injury cannot be avoided, however, it activates a series of mechanisms to repair the organism. Evidence of these systems comes from blood platelets that clot wounds to prevent bleeding out.

    Read More

  • Function and Structure of Hemoglobin and Myoglobin

    829 Words  | 2 Pages

    Myoglobin consist of single polypeptide chain that made up of 153 amino acid and ahs a size of 18 kDa. Its three-dimensional structure was first determined by X-ray crystallography by John Kendrew in 1957. Myoglobin is a typical globular protein in that it is a highly folded compact structure with most of the hydrophobic amino acid residues buried in the interior and many of the polar residues on the surface. X-ray crystallography revealed that the single polypeptide chain of myoglobin consist of entirely of eight (labelled A-H) alpha-helical. Within a hydrophobic crevice formed by the folding polypeptide chain is the heme prosthetic group. This nonopolypepetide unit is noncovalently bound to myoglobin and is essential for the biological activity of the protein.

    Read More

  • The Functions of Proteins

    923 Words  | 2 Pages

    The Functions of Proteins Introduction Protein accounts for about three-fourths of the dry matter in humans. tissues other than fat and bone. It is a major structural component of hair, skin, nails, connective tissues, and body organs. It is required for practically every essential function in the body. Proteins are made from the following elements: carbon, hydrogen, oxygen, nitrogen. and often sulphur and phosphorus.

    Read More

  • Blood Types And Carbohydrates Essay

    873 Words  | 2 Pages

    According to Karen C. Timberlake, “every individual’s blood can be typed as one of four blood groups” (556). The differences in blood is what makes every human body different from the next. Studies have shown that “people have either blood group A, B, AB, or O, with each type occurring at different frequencies in populations around the world” (Ananthaswamy 15). An individual with one type of blood cannot share blood or organs with an individual of a different blood type. Failure to distinguish different blood types can cause reject when a patient receives the wrong type from a donor. Certain methods are used in determining what type of blood a patient has. However, there are certain blood types that can accept any type of blood, and there are also blood types that can be used for any type of patient. There are many different characteristics used for categorizing blood, such as blood types, agglutination, carbohydrates, antigens and antibodies.

    Read More

  • Portfolio Reflection on Hematology

    2140 Words  | 5 Pages

    sometimes a slide will show no platelets when in fact there are plenty of platelets, they

    Read More

  • The Importance Of Protein Nutrition

    1374 Words  | 3 Pages

    Moderation is vital in all aspects of life and is necessary for overall health, including with one’s food intake. Protein is one of the many important nutrient building blocks that is necessary for proper growth and good health. However, eating excessive amounts of any nutrient or inadequate amounts, can cause various health concerns. Scientists have been able to estimate the amount of nutrients that the body requires. However, the amount of any particular nutrient varies from person to person, depending on your “age, sex, general health status, physical activity level, and use of medications and drugs” (Schiff 2013). It is also important to remember that consuming the required amount of nutrients that meets your dietary guidelines does not

    Read More

  • Human Blood Essay

    1048 Words  | 3 Pages

    The white blood cells destroy any unfamiliar pathogens in the bloodstream and can cause inflammation. Therefore, the inflammation causes a surplus of white blood cells to clot the wound for healing.

    Read More

  • The Nature of Proteins

    1233 Words  | 3 Pages

    The Nature of Proteins Proteins consist of carbon, hydrogen, oxygen and also nitrogen. Proteins are macromolecules. They are constructed from one or more unbranched chains of amino acids; that is, they are polymers ( Compound whose molecule consists of many repeated units linked together). A typical protein contains 200-300 amino acids but some are much smaller (the smallest are often called peptides) and some much larger.

    Read More

More about Proteins: A Macromolecule In Blood

Open Document