The most exceptional trait about nanomedicine is its capability of eliminating cancers and tumors. Cancers and tumors have been a major problem for people worldwide, from families being torn apart, loved ones vanishing, and much more. Both being a complex matter to challenge as for many years it has been a problem and the closest thing that was thought to be the answer was chemotherapy. Many people have been wanting the actual cure and now we might have the answer. In the article “Nanomedicine”(2014), Guizhi Zhu, Lei Mei, and Weihong Tan establishes that:
… liposome-based combination chemotherapy delivery system that can simultaneously deliver two synergistic chemotherapeutic drugs, erlotinib and doxorubicin, for enhanced tumor killing. Erlotinib,
…show more content…
They are so miniscule that terraining through nerves and cells won’t be a hassle. Also that once the nanoparticle is in the cancer cell or tumor it will stay and keep the combined drugs contained since it is both; deep inside the cell or tumor and can distribute a certain amount of drugs. While they are helpful during the process of curing. Nanodetectors are able to create bioimaging of various things that are going on in your body. Right now the use of it is to detect cancers, diseases, tumors, and much more. This gives the doctor an idea on what the situation is looking like. As Zhu, Mei, and Tan implies that, “… nanodetectors, researchers can add recognition probes such as aptamers—short synthetic nucleic acid strands that bind target molecules. Circulating tumor cells (CTCs) are shed into the bloodstream from primary tumors and provide a potential target for early cancer diagnosis” (https://www.the-scientist.com). This meaning that you’ll clearly see when tumors are expanding and traveling throughout your body. This was problematic sometimes as you wouldn’t be able to know whether or not it was spreading. Or that the doctor would think that the tumor was gone in the initial spot but then end up regrowing in another place. A great thing about nanodetectors is that you’ll be able to see early stages of cancer cells and
Vemuri S. & Rhodes CT., 1994. Preparation and characterization of liposomes as therapeutic delivery systems: a review. Pharmaceutics Acta Hebetiae, 70, 95-111.
U.S. Congress, Office of Technology Assessment. 1990. Unconventional Cancer Treatments, OTA-H-405. Washington, D.C.: U.S. Government Printing Office.
Ketoprofen proliposome formulations using pearlitol SD 200 and different ratios of HSPC and cholesterol were prepared. HSPC (a high phase transition temperature lipid) and cholesterol (for structural rigidity) were selected because of their lower risk of oxidation and improved stability of liposomes respectively. However any variation in the composition of HSPC and cholesterol results in the deformation of vesicle, which leads to drug leakage and fusion of vesicle with gastrointestinal epithelium (32). To conquer the lipid to cholesterol composition in developing stable proliposomes varying ratios of HSPC to cholesterol (total lipid mixture of 250 µM) were investigated.
The main target of this research are two main groups, the spectators and the athletes. These are two important stakeholders being affected by decisions related to nanotechnology’s use in sports. The fans and spectators of sports were reached through an online survey. By posting the survey on multiple websites and forums I was able to reach out to different people in different countries and get a representative opinion about the given issue. The athletes on the other hand were approached through a focus group and one-on-one interviews. The opinion of these two groups is important to address the gap mentioned above since an agreement must be reached to what extent nanotechnology should be allowed or not. Moreover, this research will focus on Egyptian athletes and fans because Egypt is a developing country and one of the aims of this research is to try to see if developing countries will be able to benefit from nanotechnology in sports rather than developed countries.
Wang, K., Wu, X., & Huang, J. (2013, February 28). Cancer stem cell theory: therapeutic implications for nanomedicine. Retrieved December 12, 2013, from http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589204/
Van, d. B., Brouwer, M. C., Thwaites, G. E., & Tunkel, A. R. (2012). Advances in treatment of
Cancer in one way or another touches all of us, whether as a patient or through the diagnosis of the people you love around you. Millions of patients who are faced with cancer are depending on oncologists everywhere to cure cancer so others will not suffer like they had to. Optimistically, sooner rather than later this international problem will come to an end. There are a number of drug companies that have been coming out with cancer treatment drugs. “Oncology has been one of the hottest and most active therapeutic areas for drug development, drug makers may want to take note of a finding that new cancer drugs have proven far more difficult to gain approval than medicines for infectious and autoimmune diseases.” (nature.com) Unfortunately, these drugs cannot cure the cancer but it sure makes it a load easier o...
Nanomedicine is offering incredible and innovative therapies like cancer nanomedicine, nanosurgery, and tissue engineering. In cancer nanomedicine, they use “targeted drug delivery” to target the tumor itself and avoid harming the normal, healthy cells (Berger, 2017). This in return, offers a more effective treatment with better outcomes and less side effects. In cancer nanomedicine, nanoparticles are used as tumor destroying mediators that use high temperatures to destroy them. These nanoparticles have to be injected into the tumor, then they have to be activated to produce this heat and then they are destroyed via a magnetic field, X-rays, or light (Berger,
Almost everyone is touched by cancer in some way and the number of people living with and beyond cancer grows greater every year. Globally 14 million people are diagnosed with cancer each year and 8 million people will die from it annually. Half of all men and one-third of all women will develop cancer during their lifetime. (13) There are many treatments for cancer, mainly: surgery, radiation and chemotherapy. These traditional treatments have many negative side effects. Therefore, increasingly, other treatments, such as hormonal therapy and targeted therapy are being used for certain cancers. Nanotechnology is a form of targeted therapy that destroys cancer tumors with minimal damage to healthy tissues and organs. Scientists are already using nanotechnology in early detection of elimination of cancer cells before they form tumors. But the real game changer will be when nanotechnology targets cancer tumors in treatment (11,13).
West, B. S., & Stanley, D. R. (2011). Lung cancer treatment. New York: Nova Science Publishers.
“Since 1990, over 6 million Americans have died of cancer, more than the combined casualties from the Civil war, WWII, and the Vietnam and Korean conflicts combined” (Faguet, p. 5). According to American Cancer Society projections, there were 1,529,560 new cases of cancer in 2010. Cancer is becoming more and more common around the world. New cancers are constantly being discovered. Researchers are finding new ways to detect cancer and treat it so that the fatality rate does not rise. However, there are some cancers that researchers have not yet discovered a cure for. It is very important for Cancer Research to continue so that one day these cancers will no longer be a treat.
Furthermore, current marketed liposomal doxorubicin features pegylation, in which liposomal doxorubicin is pegylated or otherwise known as coated with polyethylene glycol (13). The polyethylene glycol impedes detection by the mononuclear phagocyte system allowing it extended circulation periods without elimination (7, 13). Increases in circulation period compound aid to liposomes EPR effect in accumulating within cancerous
Nanotechnology includes nanorobots which are so small that they can be injected into the human bloodstream after which the nanorobots can do investigations or repair at cellular level. Nanorobots could optimize the delivery of pharmaceutical products, these means that medicines which are targeted on a specific type of cells can be delivered to only those cells by the nanorobots. The robots can attach to the cells after which they can inject the drug into the target cells. This could be a great breakthrough for cancer treatments such as chemotherapy because there is a minimal chance of injecting healthy cells with the drug and therefor negative side effects can be avoided.
We have already created micro robots that can enter the human body. We have also made genetic modification to fruits and vegetables. Third, we are creating nano technology so it can destroy cancer cells. In the end what will we really use them for after curing cancer. This technology can be used for war, and the government could use it to take control of cities. Will we be safe from technology? It's up to our government to decide on what to do.
I have chosen nanotechnology as my topic area of choice from the food innovation module.