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Radiation therapy quizlet
Radiation therapy quizlet
A lecture on hematopoeisis
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As the healthcare field continues to grow and evolve at an accelerated rate, new and advanced technologies are sprouting up everyday and becoming increasingly commonplace. A technology that has garnered both positive and negative attention is transplanting stem cells. Hematopoietic stem cells refer to the body's blood forming blood cells (American Cancer Society, 2013). Here is some background information on these types of stem cells. These cells are young and immature.
Stem cells mostly live in the bone marrow (the spongy center of certain bones), where they divide to make new blood cells. Once blood cells mature, they leave the bone marrow and enter the bloodstream. A small number of stem cells also get into the bloodstream. These are called peripheral blood stem cells. (American Cancer Society, 2013).
Stem cells are unique because they are pluripotent meaning they can give rise to all cell lineages.
Disease can damage blood marrow and tissue. In order to repair this damage, doctors can transplant the stem cells described above into the patient in need. There are a few different names for this kind of transplant procedure. They are: bone marrow transplant, a peripheral blood stem cell transplant, and a cord blood transplant (American Cancer Society, 2013). The process of transplanting these hematopoietic stem cells involves a number of complex steps. The first step involves the patient receiving chemotherapy and/or radiation, which kill the diseased cells. This “conditions” the area (Dana-Farber Cancer Institute, 2014). Next, healthy stem cells are infused into this conditioned area. “These transplanted stem cells will begin to grow and produce healthy red and white blood cells and platelets” (Dana-Farber Can...
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...l Studies. PLOS Biology:. Retrieved March 26, 2014, from http://www.plosbiology.org/article/info%3Adoi%2F10.1371%2Fjournal.pbio.1001738
Stem Cell Research. (n.d.). Stem Cell Research. Retrieved March 26, 2014, from http://www.citelighter.com/science/medicine/knowledgecards/stem-cell-research
Stem Cell Transplant - Dana-Farber Cancer Institute. (n.d.). Stem Cell Transplant - Dana-Farber Cancer Institute. Retrieved March 26, 2014, from http://www.dana-farber.org/Adult-Care/Treatment-and-Support/Treatment-Centers-and-Clinical-Services/Stem-Cell-Transplantation-Program.aspx
What are stem cells and why are they transplanted?. (n.d.). What are stem cells and why are they transplanted?. Retrieved March 26, 2014, from http://www.cancer.org/treatment/treatmentsandsideeffects/treatmenttypes/bonemarrowandperipheralbloodstemcelltransplant/stem-cell-transplant-what-are-stem-cells
... it, which destroys all healthy bone marrow in the body. As a result of this, the patient will have to undergo a process to replace all deteriorated or damaged bone marrow. This process involves taking the stem cells from a donor and transplanting them into the patient’s body, so that the patient will transform these stem cells into bone marrow. Bone marrow can also be a complication for the body if it escapes into the blood stream. If the bone marrow enters the blood stream, it can travel throughout the body, and cause serious complications. This is a condition referred to as fat embolism, and mainly occurs after serious trauma or surgery to lower limbs. There is not a specific diagnosis or treatment for this; it is mostly based on the patient’s condition or symptoms. Bone marrow can be a very dangerous thing if it has any type of complications within the body.
Stem cells are the building blocks of the human body. Embryos consist of unspecialized stem cells that transform into the various specialized cells in the body such as cardiac, muscle or bone cells. Fetuses also have stem cells. However, the stem cells are divided into types like muscle, bone or nerves and don't perform a specialized function. Surprisingly, adult bodies also contain stem cells. In adults, stem cells are undifferentiated but limited to specific tissue type. When needed, the stem cells transform into the cells needed for repair and maintenance. The most common source of adult stem cells is bone marrow. Researchers also acquire stem cells from umbilical cords. Without stem cells, embryos could not develop into fetuses and adult
The body is composed of cells, which form the basic unit of life. Unique cells found in the body are the stem cells. These cells are biological cells that are not specialized for particular functioning in organisms. They can be distinguished since they have the ability to differentiate or divide into multiple body cells, and their ability to replicate self. They are unique in the way they can renew themselves by undergoing cell division when inactive for a long period. It is also possible to induce stem cells to organs or tissue cells under some conditions. When the cells divide, they replenish the cells in a living organism. They serve as an internal system that repairs and replaces the tissues that are worn out.1 Dividing cells may remain as stem cells or become specialized in their functions, for instance red blood cells, brain or muscle cells.
According to Courtney Farrell’s overview of stem cell research, stem cells are undifferentiated cells that can be used to fix and replace other kinds of cells that are missing or damaged, and they can be derived from several different sources. The first of these sources, “embryonic” stem cells have been the source of many ethical debates because the process to gain embryonic stem cells involves the destruction of a human embryo in its early stages. Many people find this unethical and think it’s equal to human murder. According to the article by John Pearson, other types of stem cells include adult stem cells, which can be derived from bone marrow in grown adults, and umbilical blood stem cells; these are found in the blood of the umbilical cord after the birth of a baby and are becoming a great replacement for embryonic stem cells.
Stem cells can be utilized by transplant. Four principal types of physical disease that can be treated with stem cell transplants, including blood disorders, congenital metabolic disorders, immunodeficiencies, and certain cancers (Waller-Wise, 2011). Some examples of diseases include Sickle-cell anemia, Tay-Sachs’ disease, Hodgkin’s and non-Hodgkin’s lymphoma, certain leukemias, and many more (Waller-Wise, 2011). It is recommended that persons with family history of any of the known diseases that can be helped with stem cell transplants consider cord blood banking. Insurance companies will need to know that funding banking for cord blood is going to have more benefits than risk.
Stem cell therapy is a controversial topic that falls on the list of things not to discuss over thanksgiving dinner, very much like religion and politics. While the potential of stem cell research and therapy stand to make leaps of progression in cures for disease like Cancer and Alzheimer’s; Pros, Cons and morality still surround the issue.
Stem cell research is a heavily debated topic that can stir trouble in even the tightest of Thanksgiving tables. The use cells found in the cells of embryos to replicate dead or dying cells is a truly baffling thought. To many, stem cell research has the potential to be Holy Grail of modern medicine. To many others, it is ultimately an unethical concept regardless of its capabilities. Due to how divided people are on the topic of stem cell research, its legality and acceptance are different everywhere. According to Utilitarianism, stem cell research should be permitted due to the amount of people it can save, however according to the Divine Command of Christianity, the means of collecting said stem cells are immoral and forbidden.
Stem cells have the ability to transform into any kind of cell. These cells can divide and also replenish other cells in the body, such as muscle cells, brain cells, red blood cells, or they may just simply remain as stem cells. Stem cells are able to replicate even after long periods of dormancy. They naturally repair damaged tissues and can be experimentally induced to work with particular tissues and organs (NIH, 2013). There are three types of stem cells.
Stem cells help us to maintain and heal our bodies, as they are undifferentiated cells, their roles are not yet determined. They have the ability to become anything during early life and growth. Stem cells come from two sources, namely: embryonic stem cells (embryo’s formed during the blastocyst phase of embryological development) and adult stem cells (see figure 3).
In 2013 about 580,350 Americans were projected to die of cancer, almost 1,600 people a day. Cancer remains the second most common cause of death in the US, accounting for nearly 1 of every 4 deaths (Cancer Facts). Doctors and scientists are always trying to discover new ways to help battle cancer as well as other diseases. Doctors have tried everything from plants to radiation to try and destroy cancerous cells. Instead of destroying them Scientists and doctors are now trying to replace the old cancerous cells. In order to replace these cells they will need new cells. Stem cell research is the newest way doctors are trying to help with diseases. There are different types of stem cells. Stem cells are cells found primarily in embryos, and they have not yet taken on the characteristics of any particular type of cell, such as bone, muscle tissue or brain matter. The newest research being done is with embryotic stem cells. Embryotic Stem cells have been used in medical therapies to aid patients with many types of diseases; that being said it is imperative that we continue researching, practicing, and funding these medical advancements.
Stem cells come from adult stem cells, and embryonic cells. Embryonic (blastocyst) stem cells come from embryos that are usually three to five days old. They contain 150 cells that are useable for stem cell research. These embryos are usually created as in vitro fertilization (a bunch of eggs that are fertilized but only one is put inside of a woman). Reproduction happens when a male’s sperm is fertilized in a woman’s egg to create a zygote (cell). Scientists can verify the cells are embryonic by them being able to be duplicated and the cells ability to become other cell types; this makes embryonic cells flexible. Adult stem cells are found in adult tissues in very small numbers. These cells are only used in certain areas where they are found such as bone marrow or adipose tissue (fat).
Mayo Clinic Staff. "Stem Cells: What Are They and What Do They Do?" MayoClinic. Mayo Clinic, 13 May 2013. Web. 25 Apr. 2014. .
Stem Cell Basics. In Stem Cell Information [World Wide Web site] Bethesda, MD: National Institutes of Health, U.S. Department of Health and Human Services, 2009 [cited Friday, November 08, 2013] Available at stemcells.nih.gov
...oll(2010), around 33% of U.S. voters believe that taxpayers’ money should be spent on embryonic stem cell research and more than 50% of the voters disagree that taxpayers’ money should go the research(Roe, 2010). Hence, it is believed that government should not fund the stem cell research.
The first successful case of stem cell therapy in human was reported in 1959. Bone marrow restorations were observed in leukemia patients who received total body irradiation subsequent by intravenous injection of their twins’ bone marrow (Thomas et al, 1957). Nevertheless, that effect was transient and the following bone marrow transplantation attempts in non-twin patients and donors can eventually lead to patient’s death from graft-versus-host disease (Mathé et al, 1965). During that time, the safety of hematopoietic cells transplantation was not guaranteed because of the limited knowledge in human histocompatibility and immunosuppression. However, the turning point came after the discovery of human leucocyte antigen (HLA) groups (Dausset, 1958; van Rood et al, 1958), HLA typing and compatibility testing were performed prior to the transplantation. In addition, the improvement of immunosuppressive protocol also helps bringing the bone marrow transplantation to become more and more successful (Donnall and Hutchinson, 1999).