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Alexander Fleming's words when he invented penicillin
Was science the main factor in the development of penicillin
History of medicine essay
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Medicine today is required for almost anything, from a simple cold, to a fever, to something more serious such as recovering from a surgery. Antibiotics have become mainstream objects that are taken for granted, yet there was a point in time where medicine was not as accessible or numerous as it is now. An extremely effective medicine that is used widely today but did not exist until somewhat recently is penicillin. It kills bacteria and fights off infections, clearing the body of any diseases that it might have. The medicine now known as penicillin had a purely accidental discovery, and its use is to prevent any bacteria from spreading. Initially, it was a French medical student, Ernest Duchesne, who noticed penicillin in 1896. However, it was Alexander Fleming who re-discovered and popularized it in 1928 through a series of purely coincidental events. When he left for a one month …show more content…
It also had to be produced in practical amounts or only a trivial amount of people would be able to receive this medicine. Howard Florey and Ernst Chain began the effort of devising a way of using penicillin in humans. Part of the reason this drug was needed was to reduce the bacterial infections in soldiers’ wounds from World War II. The nature of the medicine is to stop the growth of bacteria, so in the wound it would prevent any infection from spreading, sparing the life of the soldier. However, to be able to treat the vast number of injured soldiers, a better method of producing penicillin would have to be developed. This method was to pump air into deep vats containing corn steep liquor and adding other key ingredients, which produced penicillin faster and in larger amounts than with the surface-growth method. With a clear purpose for penicillin and a way to produce it in significant amounts completed, the medicine could then be used for treating the wounded soldiers and saving countless
The Factor of War in the Development of Penicillin The discovery, development and subsequent use of penicillin can be considered to be one of the most important breakthroughs in medical history. There were many factors, which were involved in the development of penicillin, and it could be argued that war was the most important, but other factors were also responsible. Alexander Fleming was working in London as a bacteriologist in 1928 when he noticed that a growth of a mould called penicillin produced a substance that actually killed the germs he was working on. He realised that this might be very important and a year later he wrote an article about his findings. However, Fleming did not have the facilities or the support to develop and test his idea that penicillin could fight infection, and he didn't develop it further.
Adegoke AA, Tom M, Okoh AI, Jacob S (2010) Studies on multiple antibiotic resistant bacterial isolated from surgical site infection. Scient Res. Essays 5:3876-81.
Penicillin, derived from the mold Penicillium, is the first antibiotic to successfully treat bacterial infections on humans. It was accidentally discovered by scientist, Alexander Fleming. While Fleming was growing Staphylococcus, a serious and often deadly infection, in a dish, he noticed the bacteria had stopped growing after a mold found its way
Years later other scientists were also intrigued by the possibilities of penicillin and produced enough penicillin to prove that it was a useable antibiotic. The scientists from Great Britain were developing all of this during World War II, and unfortunately funding for their drug was unavailable due to the war. They decided to bring their concepts to the United States, and once enough was made, it was eventually used, to treat wounded soldiers during World War I.
Penicillin became the first manufactured antibiotic after physician Alexander Fleming published articles regarding this bacteria-disabling mold in 1928. Come 1932, penicillin was commonly used to treat infected war injuries, saving the lives of unnumbered soldiers (Lewis). Since then, penicillin has become a popular treatment for numerous infections ranging from respiratory illness to syphilis. As society realized the benefits of penicillin, physicians began producing antibiotics to fight an infinite number of illnesses.... ... middle of paper ...
Having an ear infection in 2015 is no big deal. You hop in your car and drive to your doctor’s office. Your doctor sees you, diagnoses you with an ear infection and prescribes you, penicillin like they have dozens of times before. Today penicillin and other antibiotics are taken for granted. Before the 1920’s bacterial infections would do a lot more harm than just having an ear ache. If penicillin was not invented who knows how delayed today’s medicine would be.
18). Even though those diseases were not his goal to cure it still made penicillin revolutionary for the time being. Fleming now knew how to make penicillin and started to mass produce it. In the 1930s during the upgrading process of penicillin Fleming himself was cured of severe conjunctivitis. Then in the 1940s the fully developed penicillin was created. The creation of penicillin cured a wide variety of diseases, which led to the world excelling in growth, and penicillin improved the way of medicine at the time. The variety of diseases cured by penicillin made it a must have antibiotic. Penicillin was used to cure multiple diseases including syphilis, gonorrhea, tuberculosis, gangrene, pneumonia, diphtheria, and scarlet fever ( Common Antibiotics ). All the diseases have one thing in common, they all have the ability to spread, some faster than others. When a disease is discovered people tried to make a cure. When penicillin was made diseases that were thought to never have a cure were cured. People began to demand that penicillin be sold in local pharmacies. Penicillin was released to help people with the variety of diseases curable by
Ernest Chain and Howard Florey with the knowledge of Flemings work were able to successfully purify an extract of penicillin for testing. The tested it in 1940 on mice, they concluded that those who were given the penicillin lived whereas the others did not. Later in 1945 all three men received the Nobel Prize for their contr...
The controversy regarding the sub-therapeutic use of antibiotics in animal feeds is that “super-bugs” are able to evolve. This is a threat to both the health of the animals and humans. What a “super-bug” refers to is a strain of bacteria that has evolved to be resistant to bacteria and lethal to the host organism. These super-bugs account for the death of roughly 48,000 Americans each year (Adams, 2013). These superbugs proliferate in the digestive tracts of hosts. Each dose of antibiotics in the animals’ diets at sub-therapeutic levels increases the likelihood of antibiotic resistance bacteria to evolve. The antibiotics kill the antibiotic sensitive bacteria, but bacteria that are resistant proliferate in the gut of the animals. When these antibiotic resistant bacteria are left to grow in the gut, they can cause infection to the animal or people that consume the animal as food (Falco, 2013, Amachawadl et. al. 2013). Antibiotic-resistance can also be conferred through horizontal gene transfer and other methods, making the mere existence of such bacteria a threat that should not be taken lightly.
Alexander Fleming started the history of antibiotics in the 1920's with his discovery of penicillin.When penicillin was first discovered and used widely, it was touted as a wonder drug, and consequently was used as one.Though not necessarily harmful to the patient penicillin was used for much more infections than it was able to combat.Today the same practice is observed in the medical profession, however at this point it is due more to the detriment of an uneducated public.Studies have been carried out that show the huge over usage of antibiotics.In the seventies Soyka et al, concluded, "60% of physicians surveyed gave antibiotics for the treatment of the common cold."[3], and by common knowledge the common cold is a virus, something that cannot be treated by an antibiotic.Nyquist
To start off, Alexander Fleming was never a clean or organized person. His laboratory was always scattered with molds and bacterial cultures. According to “The Discovery of Penicillin: The True Story”, it states that when, “..he returned from his vacation in 1928...he
Discovery and Development of Penicillin. (2014, April 4). Retrieved from American Chemical Society International Historic Chemical Landmarks: https://www.acs.org/content/acs/en/education/whatischemistry/landmarks/flemingpenicillin.html
The discovery of Germ Theory eventually led to the discovery of the first antibiotic, penicillin, by Alexander Fleming in 1928 (Nobelprize.org, 2014). The development of the first commercially available antibiotics led to a massive drop in infection-related death rates in common procedures such as routine childbirth as seen in Figure
He observes that Ernest Duchesne had discovered penicillin during the 1890s, but his findings were not acknowledged as he was unknown and young, and unfortunately he died fifteen years later; penicillin was not rediscovered again until thirty-two years later by Scottish scientist Alexander Fleming, who was unaware of Duchesne’s discovery (Thompson 61). Unfortunately, many lives were lost all those years before penicillin was rediscovered and because both Duchesne and Fleming did not have access to a medium that allowed them to easily share ideas. Thompson further addresses his observation by providing several other
The discovery of antibiotics is attributed to Alexander Fleming who discovered the first antibiotic to be commercially used (Penicillin) in approximately 1928. An antibiotic, also known as an antimicrobial, is a medication that is taken in order to either destroy or slow the growth rate of bacteria. Antibiotics are integral to the success of many medical practises, such as; surgical procedures, organ transplants, the treatment of cancer and the treatment of the critically ill. (Ramanan Laxminarayan, 2013)