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Pathophysiology of polycystic ovary syndrome Up to date
Pcos pathophysiology
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Evidence Based Project: Polycystic Ovary Syndrome
Polycystic ovary syndrome (PCOS) is a difficult, life changing condition for many women (Madnani, Khan, Chauhan & Parmar, 2013). In the United States alone, PCOS affects approximately 5 million women of childbearing age. The price tag to the health care system for PCOS identification and management is approximately 4 billion dollars yearly (National Institute of Health Office of Disease Prevention, 2014).
Background Information
Polycystic ovary syndrome (PCOS) is a complicated condition that involves the endocrine system. Research have shown that it is a condition that is often present in women of reproductive ages, its main cause is not fully understood, but researcher have speculate that it is mainly a result from factors such as obesity, excessive insulin production and genetics. Women with this condition often present with excess androgen production, irregular periods, and polycystic ovaries-enlarged ovaries which contain fluid. Because of the excessive androgen production ovulation problems, acne, excessive body, facial hair (Hirsutism), baldness and increased obesity occur (Legro, Arslanian, Ehrmann, Hoeger, Murad, Pasquali, & Welt, 2013). Another entity that is present with PCOS is abnormally
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increase insulin production (Legro et al., 2013). Typically, symptoms of PCOS includes excessive body hair on areas such as the back, face, stomach chest, toes ( hirsutism) which normally does not occur in women. Other symptoms includes infertility, excessive weight gain, sleep apnea, ovarian cyst, irregular menstrual cycle, and pelvic pain, (Legro et al., 2013). The diagnosis of PCOS is usually made due to exclusion of other disorder, presentation of oligomenorrhea and or anovulation and clinical or biochemical evidence of hyperandrogenism and or polycystic ovaries (Roe, Prochaska, Smith, Sammel, & Dokras, 2013). Significance of the Problem PCOS negatively impacts woman’s quality of life and increases their risk for morbidity such as, cardiovascular disease, diabetes, hyperlipidemia, hypertension, increased obesity, infertility and endometrial and breast cancer. Having PCOS along with these morbidity leads to more health problems, which intern increases the cost to the health care system. PCOS burdens to women and the health system as a whole makes it an area of interest (National Institute of Health Office of Disease Prevention, 2014). The Relevance of PCOS PCOS is relevant to this writer’s role as an advanced practitioner because of its high prevalence, it being the most common endocrine disorder among female, ages 18 to 44 years and its associated reproductive and metabolic complications (National Institute of Health Office of Disease Prevention, 2014).
PCOS symptoms can drastically affect a women’s wellbeing and mental state, which increases her risk for developing anxiety and depression. There is also the effect of social and marital maladjustment and sexual dysfunction. Overall PCOS offers a reduction in health related quality of life for women, which makes it a relevant topic to this writer’s role (Bazarganipour, Taghavi, Montazeri, Ahmadi, Chaman, & Khosravi,
2015). Role of Advanced Practice Nurse The role of the advanced practice nurse is to manage PCOS appropriately, to optimized health promotion and the best quality of life physically and mentally (Bazarganipour et al., 2015). Since a main contributor of PCOS is obesity, advanced nurse practitioners should promote lifestyle changes, which includes healthier eating habits, increased exercise and weight loss as a priority in women with PCOS (Bates & Legro, 2013).
Congenital Adrenal Hyperplasia (CAH) is an inherited condition that affects hormone production in the adrenal gland. The individual lacks enzymes to make cortisol, and hormones are instead are shifted away to make other hormones, specifically androgens. This results in the deficiency of cortisol and the abundance of testosterone.
“High levels of hormones can cause problems in the human body, but can hormones we ingest really alter our hormone level...
Is it time to bring OCs over the counter?. (2010). Contraceptive Technology Update, 31(7), 77-
Polycystic Ovaries Syndrome can cause a number of symptoms. Its can cause everything from obesity to missed periods. It also causes women to have more of the male hormone in their bodies, which cause male hair growth. Not all of PCOS patients have excessive hair growth some may have other skin conditions, like acne. PCOS is the one of the most notorious cause if missed menstrual cycles and “infertility due to the lack of ovulation”. (Thatcher, 12)
Polycystic Kidney Disease, also known as PKD, is a common inherited gene disorder that causes the growth of cysts in the tissues of both the kidneys. The kidneys are a major organ in the excretory system; they remove wastes from the blood and form of urine. They filter the blood, keeping it clean of all wastes and have a number of other functions as well. Due to the growth of cysts on the kidneys it makes it hard to carry out these functions and the will eventually cause the kidneys to fail. This paper will discuss what PKD is, the many symptoms and treatments of PKD, and recent developments in research of this disease.
Most people appreciate their hair as the most valuable assets especially for women. However, there are so many problems related to this precious thing nowadays such as hair loss (alopecia), dandruffs and premature greying and balding. The researcher’s team headed by Professor Markus Nothen from University of Bonn and Dr. Roland Kruse from Dusseldorf University in 2005 discovered that the main cause of alocepia is hereditary factors which either because of high androgen receptor formed or variant receptor which develops as a result of genetic change. In addition according to Hoffman (2002), “The most common form of alopecia in men is believed to be due excessive activity of androgens on the scalp where the hairs become miniaturized and pigment production is stopped.” Hamilton (1951); Hoffman (2002); Price (2003); Severi et al., (2003) claimed that conversion towards more potent testosterone is due to elevation level of 5-alpha reductase lead to common baldness. For the genetically derived phenomenon, it supposed to be totally about the hereditary cause and the other exogenous factors will be excluded. However, there are also views from proponents saying that some natural food involves in solving these hair—related problems for example emblica officinalis or amla.
Other topics mentioned in Oakley’s review were also the three unsolved problems with women and health. She listed the three following topics regarding production, reproduction, and medicalization of psychological costs of women’s mental diseases. She also researched health vs. social product amongst women.
In conclusion, it is important women are aware of the severity of pelvic inflammatory disease, and be concerned with the damage it can do to the female reproductive system.
Because of this, she does seem to have metabolic syndrome. With metabolic syndrome, concomitant disease states occur that the patient may have, including PCOS, and hypothyroidism.
The cause of endometriosis continues to remain unknown. It has been researched for many decades and...
Life is a roller-coaster to a destination unknown. As we grow up we dream and plan our lives which involve our careers, families, and our future lifestyles. Unfortunately not everything we plan comes true there are bumps and hurdles in life. Some just make us stumble while others are crippling. One of those crippling wonders of life is known as Infertility. Infertility is defined as “not being able to become pregnant after a year of trying. If a woman can get pregnant but keeps having miscarriages or stillbirths, this too is known as Infertility” (NIH: National Institute of Child Health and Human Development). It is a growing problem, year after year the number of people effected increase. “Infertility affects 80 million people worldwide” (Peddie,Porter). I am of that eighty- million, so is my sister, and my mother. To the many people that suffer from Infertility it is personal, affects the community nationally, and needs our understanding.
Depression is most common in women. The rates are twice as high as they are in men. According to the National Mental Health Association, about one in every eight women will develop depression at some point during her lifetime. Women’s symptoms are similar to major depression. Some of them include being in a depressed mood, loss of interest in activities you used to like, feelings of guilt and hopelessness, and suicidal thoughts or recurrent thought of death. Women tend to blame themselves, feel anxious and scared, and avoid conflicts at all costs. They also use food, friends, and love to self-medicate. Some causes of depression in women are premenstrual problems, pregnancy and inf...
This journal was useful for me because it gave me the background details on why women are opting for delayed motherhood by the age of 30 or 40. Accordingly, I was able to build up my points on how it will affect the health conditions of both baby and mother and also the risk of taking that challenge.
...ian Syndrome (PCOS) is one of the most common female endocrine conditions. It affects about 5 to 10 percent of women of reproductive age14. Women who have PCOS often suffer from high levels of hormones called androgens – a steroid hormone that regulates the development of male characteristics-14. This syndrome results in obesity, excessive hair growth, reproductive problems and other health issues.