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Pathophysiology of parkinson disease essay
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Parkinson’s Disease
Parkinson’s disease has become front page news as of late. It has caught the attention of many due to its unrestricted and devastating effects. People from all walks of life can suffer from the disease. It has no economic, social, or religious boundaries. Well known celebrities such as Muhammad Ali, Michael J. Fox, Estelle Getty, Billy Graham, Janet Reno, Pope John Paul II, and Johnny Cash, among many others, have fallen victim to this debilitating ailment. Because Parkinson’s disease is “one of the most common neurologic disorders of older adults” (Ignatavicius & Workman, 2016, p. 867), it is important to review and learn about this disorder. Parkinson’s disease affects approximately four million people worldwide and
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It “is a progressive neurodegenerative disease that is the one of the most common neurologic disorders of older adults” (Ignatavicius & Workman, 2016, p. 867). The brain is the primary organ involved. In the area of the brain called the substantia nigra, dopamine producing cells are damaged or destroyed. Because there is a diminished number of the dopaminergic neurons, dopamine production is decreased. Dopamine is a neurotransmitter responsible for relaying messages to other neurons. Dopamine, together with acetylcholine, work to polish and synchronize movement allowing for smooth, purposeful physical motion. As one neurotransmitter, acetylcholine, elicit a response; the other, dopamine, inhibits it. This works as a well balanced act to control voluntary movement. The decrease in dopamine is what gives Parkinson’s disease its characteristic. Four chief signs are found in Parkinson’s disease: tremors, especially when at rest; muscle rigidity; bradykinesia or akinesia, slow movement which can lead to muscles freezing or no movement especially facial muscles in which the individual adopts a mask like feature called hypomimia; and impaired posture and balance, individuals lose coordination increasing the risk for …show more content…
At the first sign of trouble, the doubt and anxiety starts to creep in. Patients and family member can experience the emotions that goes along with loss such as denial, disbelief, and some times shock. They can become discouraged to learn that Parkinson’s is a non curable disease. As their abilities diminish and worsens, depression and anger can become part of their coping mechanism. Their doubt about their ability to support their family, drive, participate in activities, interact with their loved ones, and communicate is a valid one and deserves attention. Family dynamic is impacted and some family members might experience a role reversal. Special attention must be placed on the caregiver as well. Caregiver role strain can go unnoticed if one does not play close attention. Educating both the patient and the care giver is of outmost importance as to provide resources that can make their life a bit more predictable and
Many people, like myself, after watching an episode of “The Michael Jay Fox Show,” started to be come curious as to what exactly this disease is. You ask yourself; What is this disease? What causes it? Can it be passed down from generation to generation? Is there a treatment? What would your life be like suffering from this? Through my research on Parkinson’s disease, I am determined to answer these questions. I hope to have a better understanding on this disease, and how it affects the lives of patients that I might see in a hospital.
(Davidson, F. G.) Due to the nature of dementia being a neuropsychological disorder, those affected by the disease tend to look like they will not require much care, which, in reality, they often require more care than the caregiver originally expected, leading to stress and burnout. Another effect caused by this can be the caregiver blaming themselves by feeling like they are failing to give proper care, which, in reality, can often be very far from the truth. If the caregiver does not receive help from anyone else, the task of watching over the victim becomes a daunting twenty for hour task. Sometimes, the caregiver won’t be allowed quality sleep. Over 66 percent of home caregivers suffer from some form of psychological or physical illness. The most common illness that is resulted from giving care to Alzheimer’s disease is depression. The caregiver needs to monitor their emotional well-being as well as the well-being as the person that they are giving care to. Usually, giving care to those with dementia is actually more stressful than giving care to those with cancer. When the caregiver is a family member and not a professional, the emotional toll is often even greater. It is important for caregivers to remember that they need to take care of themselves first and
Parkinson’s Disease is a progressive neurodegenerative disorder in the community resulting in significant disability. This global problem has consumed the lives of many. “Approximately 60,000 Americans are diagnosed with Parkinson's disease each year, and this number does not reflect the thousands of cases that go undetected” (Statistics on Parkinson’s, 2014). Once this unbiased disease has begun to affect the patient it is a lifelong battle. Parkinson’s disease has a tremendous impact on the patient as they battle for their independence and plead for their acceptance into their own community setting. People living with Parkinson’s disease struggle with tremors, bradykinesia and rigidity. It takes a skilled nurse to be able to care for the patient suffering with Parkinson. With education, support and exercise the patient will be able to feel some sense of hope for their future. The purpose of this paper to is educate the community about Parkinson’s disease and the impact on the patient and on the nurse caring for the patient.
Parkinson's Disease is a mysterious disease that affects the central nervous system and can be very difficult to treat and live with. It is classified as a motor system disorder but is a progressive, chronic disease resulting in
With more than 200,000 US cases per year, Parkinson’s disease has become a major part
Parkinson disease (PD), also referred to as Parkinson’s disease and paralysis agitans, is a progressive neurodegenerative disease that is the third most common neurologic disorder of older adults. It is a debilitating disease affecting motor ability and is characterized by four cardinal symptoms: tremor rigidity, bradykinesia or kinesis (slow movement/no movement), and postural instability. Most people have primary, or idiopathic, disease. A few patients have secondary parkinsonian symptoms from conditions such as brain tumors and certain anti-psychotic drugs.
Parkinson's is an idiopathic, multifactorial neurodegenerative disease that attacks neurotransmitters in the brain called dopamine. Dopamine is concentrated in a specific area of the brain called the substantia nigra. The neurotransmitter dopamine is a chemical that regulates muscle movement and emotion. Dopamine is responsible for relaying messages between the substantia nigra and other parts of the brain to control body movement. The death of these neurotransmitters affects the central nervous system. The most common symptoms are movement related, including shaking, rigidity, slowness of movement and difficulty with posture. Behavioral problems may arise as the disease progresses. Due to the loss of dopamine, Parkinson's patients will often experience depression and some compulsive behavior. In advanced stages of the disease dementia will sometimes occur. The implications of the disease on the anatomy and physiology of the respiratory and phonatory systems significantly control speech.
Nurse’s play a very important role in the delivery of care to an older person and in complex disease such as Parkinson’s disease, the care provided by a nurse is vital for both the patient and the family of the affected person. The aim of this essay is to understand briefly about Parkinson’s disease and associated issues and the role of the nurse in the management of the condition.
There exists a group of people who live the final years of their lives in glass boxes. They are perfectly capable of seeing outside, but incapable of reaching out to the world around them. Their emotions can not be shown through facial expression, and as their condition continues, speech also becomes difficult or even impossible. These people are men and women of all races and geographical areas, constituting one percent of the world’s population over 50 years old. Parkinson disease is their affliction. Although Parkinsonism has been around almost as long as recorded history, there is yet to be found a cause or a cure. Medications tame the symptoms and prolong life, but are incapable of reversing the disease progression.. Diagnosis relies exclusively upon clinical signs and symptoms, because almost all laboratory and radiography tests are normal in the Parkinson patient. For this reason early diagnosis is very difficult. The fact that early signs of Parkinsonism can easily be overlooked as normal aging, further complicates diagnosis. Therefore, primary care physicians of the middle-aged and elderly population must be extremely sensitive to patients’ outward appearance and changes in movement ability.
Alzheimer’s disease is a serious disease which causes people to behave in a challenging way for their family and caregivers to manage. These behaviours are caused by damage to the brain that leads to psychological and functional impairment. Due to this impairment the people with AD are often neglected and labelled by the society. Family caregivers play a massive role in the care of their loved ones with AD. Patients and family caregivers often experience stress in dealing with all the obstacles that Alzheimer’s disease put them through.
“I’ve got Parkinson's syndrome. Now they can say,‘He’s human, like us. He has problems.” (Gale). But after all the controversy about Ali’s Parkinson’s, he decided to capitalize on this and used his popularity to try and raise awareness for Parkinson’s disease. Dr. Michael Okun who is the medical director of the National Foundation states that,“Before Ali, there wasn’t that much known about Parkinson’s disease.” Most people would mistake Parkinson’s for other disease like ALS or Alzheimer's, but Ali made it so that people would be aware that this is a major issue that needed to understood. In the 1990s, Ali began to heavily advocating for the increased government funding for Parkinson’s disease research and even donated majority of his earnings so that scientists would receive research dollars for Parkinson’s. He even started his own annual event called, Celebrity Fight Night. This too was to raise money for research and he ended up making around $100 million in donations for Parkinson’s. In 1997, Ali helped establish Muhammad Ali Parkinson Center at the Barrow Neurological Institute. For the next ten years, there were more than 23,000 research articles concerning Parkinson’s disease were published in scientific journals. And because of this, many centers, including the Muhammad Ali Parkinson’s Center, are now using mental and physical exercises for treatment for Parkinson’s
716). Characteristic features of Parkinson's disease include “motor impairment (bradykinesia, rigidity, tremor, gait dysfunction, and postural instability), cognitive impairment (frontal lobe executive dysfunction), and mood disorders” (p. 716). Normally, motor performance depends on the interaction between automatic (unconscious) and volitional (cognitive) control of movement, however those with Parkinson's disease, experience an “early and preferential loss of dopamine in the caudal regions of the basal ganglia (dorsal regions in rodents), which leads to diminished automatic and increased cognitive control of movements that include frontal lobe circuitry” (p. 716). Consequently, those with Parkinson’s disease must sustain a larger cognitive load to execute either motor or cognitive tasks, such as working memory. In the past decade, increasing evidence has accrued for the role of exercise in the improvement of motor performance, which may help both the cognitive and automatic control of movement. Thus, exercise interventions can help those with Parkinson’s disease incorporate goal-based motor skill training, which then helps in engaging circuitry important in motor learning. Individuals with Parkinson's disease become cognitively engaged with the practice and acquiring of movements and skills that were formerly automatic and unconscious. In addition, aerobic exercise is also observed as important for improvement of blood flow and assistance of neuroplasticity in the elderly, which may also play a role in the improvement of behavioral function in those with Parkinson's disease. Petzinger et al. additionally states that exercise also uses goal-based training and aerobic activity which can improve “both cognitive and automatic
Without this vital dopamine nerve cells cannot properly transmit messages resulting in a loss of muscle function.Parkinson's Disease is a non-communicable disease and doctors have not yet found out whether or not it is a hereditary disease. Parkinson's Disease has many distinct symptoms. The symptoms are:Muscle Rigiditystiffness difficulty bending arms or legsunstable, stooped, or slumped-over posture loss of balancewalking pattern changesslow movements difficulty beginning to walk difficulty initiating any...
Many people around the world today suffer from Parkinson’s disease and other movement disorders. A movement disorder is a disorder impairing the speed, fluency, quality, and ease of movement. There are many types of movement disorders such as impaired fluency and speed of movement (dyskinesia), excessive movements (hyperkinesia), and slurred movements (hypokinesia). Some types of movement disorders are ataxia, a lack of coordination, Huntington's disease, multiple system atrophies, myoclonus, brief, rapid outbursts of movement, progressive supranuclear palsy, restless legs syndrome, reflex sympathetic dystrophy, tics, Tourette's syndrome, tremor, Wilson disease, dystonia, which causes involuntary body movement, and Parkinson's disease. Parkinson’s disease, Tourette’s syndrome, and tics are one of the most widely known of these disorders, known to impair people of movements and rob them of their lives.
Leggett, A., Zarit, S., Taylor, A., & Galvin, J. (2010). Stress and burden among caregivers of patients with lewy body dementia. The Gerontologist, 51(1), 76-85.