Wait a second!
More handpicked essays just for you.
More handpicked essays just for you.
Pathophysiology of parkinson disease essay
Parkinson disease review paper
Parkinson disease review paper
Don’t take our word for it - see why 10 million students trust us with their essay needs.
Recommended: Pathophysiology of parkinson disease essay
The following paper discusses one of the most common disease of the elderly naming Parkinson's Disease. This paper reflects the basic understanding of the disease with prime focus on the course, treatment and advance health care needs of the patient. Additionally, to have a better understanding of the disease this paper puts some light on the causes and pathogenesis of the disease and how an elderly patient can cope up with his life during the last stages of the disease.
Key Words
Parkinson's disease, Elderly patient, Bradykinesia, Akinesia, Substantia Nigra, Alpha-synuclein, Rest tremor, Micrographia, Levodopa, Carbidopa, Dopamine, Frozen gait, Depression, Deep Brain Stimulation, Hospice, Living will and Durable Power of Attorney for Health Care (DPHC).
..........................................................................................................................
1. Introduction
Parkinson's Disease is a perpetual, dynamic, neurodegenerative sickness of the elderly for the most part influencing individuals at the age of 60. Nearly 5 million people are suffering from this disease all over the world and 1.2 million people are suffering in United States and Canada with approximately 480 per million people are newly diagnosed each year. This disease not only affects the patient but also it is a cause of worry among patient's loved ones and family members. Though, the news of the recent disease diagnosis haunt every individual and his nears and dears but due to several support groups and societies and several scientific breakthroughs have put a ray of hope in the life of individual living with Parkinson's disease.
2. History
The disease was commonly called as shaking palsy. In the year 1817, it was Dr. James Parkinson wh...
... middle of paper ...
.... Rest tremor is usually unilateral starting from hand and foot and the movement of the fingers and thumb is usually described as pill rolling action. As the disease progresses, the tremors spread to all the four limbs. The counter action of muscles such as contraction and relaxation is disturbed leading to muscles soreness and finally rigidity. Patients experience slowness in their routine activities and tend to fall backward due to loss of postural reflexes. Other secondary signs include mask like face, slurred speech, drooling of saliva, difficulty in writing commonly called as micrographia, constipation, depression and difficulty in swallowing. Parkinson's malady is regularly connected with psychiatric dullness, which incorporates discouragement, uneasiness, and dopaminergic psychosis. Therefore, several medications and psycho therapies are available for relief.
Many people, like myself, after watching an episode of “The Michael Jay Fox Show,” started to be come curious as to what exactly this disease is. You ask yourself; What is this disease? What causes it? Can it be passed down from generation to generation? Is there a treatment? What would your life be like suffering from this? Through my research on Parkinson’s disease, I am determined to answer these questions. I hope to have a better understanding on this disease, and how it affects the lives of patients that I might see in a hospital.
on the account of ancient Indian texts relating to the Ayurveda medical system which identified the disease as Kampavata. Many others have identified Parkinson’s throughout time as either the “shaking palsy” or its Latin form “paralysis agitans” (Abramovitz, 10). People such as Middle Age physician Galen in 175 AD and widely known Leonardo Da Vinci all picked up on the presence of Parkinson’s Disease before it’s official description was written in 1817 in
People who have been diagnosed with this lifelong disease have either started to see the early signs and symptoms or have yet to recognize them. The negative impact that fatigue, loss of muscle strength and in-coordination has on the patients with Parkinson’s disease can be improved with a well-balanced exercise regimen. The three most common physical symptoms the patient will experience are tremors, rigidity, and bradykinesia. “Tremors while at rest are the most common initial symptom and are present in around 70 percent of cases at disease onset. It often presents as a pill rolli...
The four key symptoms of Parkinson’s disease are tremors of the hands, arms, legs, or
Parkinson's is an idiopathic, multifactorial neurodegenerative disease that attacks neurotransmitters in the brain called dopamine. Dopamine is concentrated in a specific area of the brain called the substantia nigra. The neurotransmitter dopamine is a chemical that regulates muscle movement and emotion. Dopamine is responsible for relaying messages between the substantia nigra and other parts of the brain to control body movement. The death of these neurotransmitters affects the central nervous system. The most common symptoms are movement related, including shaking, rigidity, slowness of movement and difficulty with posture. Behavioral problems may arise as the disease progresses. Due to the loss of dopamine, Parkinson's patients will often experience depression and some compulsive behavior. In advanced stages of the disease dementia will sometimes occur. The implications of the disease on the anatomy and physiology of the respiratory and phonatory systems significantly control speech.
Nurse’s play a very important role in the delivery of care to an older person and in complex disease such as Parkinson’s disease, the care provided by a nurse is vital for both the patient and the family of the affected person. The aim of this essay is to understand briefly about Parkinson’s disease and associated issues and the role of the nurse in the management of the condition.
These pieces of evidence led to the conclusion of John having Parkinson’s Disease. The fact that he is an old man, who has difficulty with motor movement, tremors in his hand, and has almost illegible writing led to the diagnosis of Parkinson’s, which includes these symptoms.
The fact that early signs of Parkinsonism can easily be overlooked as normal aging, further complicates diagnosis. Therefore, primary care physicians of the middle-aged and elderly population must be extremely sensitive to patients’ outward appearance and changes in movement ability. Most signs and symptoms of Parkinson disease correspond to one of three motor deficiencies: bradykinesia, akinesia, tremor, and rigidity. The first two qualities are usually present before tremor, but often attributed to aging by the patient and even the physician, and thus the disease is rarely diagnosed until tremor becomes evident much later. An average of 80% of the nigrostriatal neurons may have already degenerated by the time Parkinsonism is diagnosed, which complicates treatment (Fitzgerald, 130).
Parkinson disease (PD), also referred to as Parkinson’s disease and paralysis agitans, is a progressive neurodegenerative disease that is the third most common neurologic disorder of older adults. It is a debilitating disease affecting motor ability and is characterized by four cardinal symptoms: tremor rigidity, bradykinesia or kinesis (slow movement/no movement), and postural instability. Most people have primary, or idiopathic, disease. A few patients have secondary parkinsonian symptoms from conditions such as brain tumors and certain anti-psychotic drugs.
Parkinsons disease Learning is defined as, a change in the capability of a person to perform a skill that must be inferred from a relatively permanent improvement in performance as a result of practice of experience (Magill 247). For healthy people to learn a skill, they must show improvement, consistency, stability, persistence, and adaptability. However, for patients with Parkinsons Disease, it is not as simple. Bradykinesia, the slowed ability to initiate and continue movements, is a well-recognized side effect of Parkinsons Disease. In Rostami and Ashayeris study, Effects of motor skill practice on reaction time and learning retention in Parkinsons Disease, they investigated whether or not short-term practice could improve Bradykinesia. Patients with Parkinsons Disease frequently spend more time not only initiating voluntary movements, but also more time carrying out the voluntary movements. Thus, the study gathered 9 patients (7 males and 2 females) with Parkinsons Disease and 9 controls (7 males and 2 females) that were healthy and disease free. The participants were instructed to look at their monitor and to carry out a hand-to-mouth reach when prompted by the random stimulus on the monitor. The researchers used the Kinemetrix 3D Motion Analysis System and three markers that were positioned on the lateral aspect of the wrist, elbow, and shoulder joints to record and analyze the movements in three-dimensional space. Though all of the participants were right-handed, they were all instructed to use their left hand to complete the task because in all of the participants the left arm appeared to be more bradykinetic. The purpose of this study was to see if reaction time coul...
Parkinson 's disease usually develops later on in life, commonly between the ages of 40-80, but also occurs in younger and older individuals. Unfortunately there is no current cure or any definitive therapy which has been shown to slow the progression or prevent the disease. Levadopa is the most standard treatment for neurological disease, nearly all patients showed signs of improvement when Levadopa is used.
James Parkinson first discovered Parkinson's Disease in 1817. Parkinson's Disease is a common neurologic disorder for the elderly. It is a disorder of the brain characterized by shaking and difficulty with walking, movement, and coordination. This disease is associated with damage to a part of the brain that controls muscle movement. Parkinson's Disease is a chronic illness that is still being extensively studied.
Parkinson’s disease – Affecting the central nervous system, Parkinson’s affects basic movement, leading to tremors. Typically characterised by shaking hands.
"Secondary Parkinsonism: MedlinePlus Medical Encyclopedia." U.S National Library of Medicine. U.S. National Library of Medicine, n.d. Web. 11 May 2014.
The study was organized and conducted at the Adele Smithers Parkinson’s Disease Treatment Center of the New York Institute of Technology, College of Osteopathic Medicine (Old Westbury, NY). A flyer was on the bulletin board in the clinic area. The study was also introduced at an exercise class. The study was approved by the New York Institute of Technology Institutional Review Board, and all participants signed written informed consent. Twenty-one Caucasian participants (19 male, 2 female) who were diagnosed with PD by a neurologist were consented to participate in this study.