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Meningitis pathophysiology paper
Meningitis pathophysiology paper
Essay of pathophysiology of meningitis
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Public Health Problem Meningitis is believed to have existed since ancient times (Mandal, 2012), and the World Health Organization (2014) continues to regard it as a global public health risk even to this present day, with the disease becoming so prominent in sub-Saharan Africa that the area itself has been dubbed “the meningitis belt”. Meningitis is a worldwide problem that demands attention and solutions. Meningitis is a disease that specifically affects the membranes of the brain and spinal cord, otherwise known as the meninges, causing the aforementioned membranes to become inflamed. With respect to its initial cause, the severity of meningitis can range from the infected being able to recover independently (with the natural performance of their immune systems alone), to potentially fatal (in which the infected will then require immediate medical attention in the form of …show more content…
There are five types of meningitis, each diagnosis classified according to their cause: viral, bacterial, fungal, parasitic, and non-infectious (developed as a result of HIV/AIDS, cancer, tuberculosis, and other diseases and conditions). The distinct symptoms that all five types of meningitis share are the symptoms originating from the inflamed meninges, which, as reported by the Mayo Clinic (2015), include headaches, fever, and stiffness of the neck as the most distinct few of the variety. As stated by the Centers for Disease Control and Prevention (2015), although meningitis is considered a relatively rare disease in the United States (with the usually nonfatal viral meningitis being the most commonly observed case), bacterial meningitis in particular is the epidemic type that is often times fatal and the most dangerous. It is contagious and it can be spread by respiratory fluids such as saliva and mucus (CDC, 2015). In some cases, it is possible for those who have recovered from this form of meningitis to suffer from acute complications that impact their
The guidelines’ first focus is the definition of sepsis, which makes sense, because there is no way to effectively treat sepsis without an accurate and categorical definition of the term. The guidelines define sepsis as “the presence (probable or documented) of infection together with systemic manifestations of infection”. Such systemic manifestations can include fever, tachypnea, AMS, WBC >12k, among others; these manifestations are listed in full in Table 1 of the guidelines. The definition for severe sepsis builds on to the definition of sepsis, bringing organ dysfunction and tissue hypoperfusion (oliguria, hypotension, elevated lactate) into the picture; full diagnostic criteria is listed in Table 2. The guidelines recommend that all
In one of the meetings with the mentor regarding altered and/or impaired homeostatic function, a case study of a patient admitted with sepsis was discussed. Assessment, care and evolving treatment provided was looked into. Following the discussion, the management of sepsis has been examined further by the learner as she was not familiar with the bundle of six sepsis mentioned by the mentor. The learner looked on the situation and reflected back on the occurrence that took place realizing if appropriate measures were implemented and how things can be different in future practice (Schon, 1987). This
My disease is Streptococcal pneumonia or pneumonia is caused by the pathogen Streptococcus pneumoniae. Streptococcus pneumoniae is present in human’s normal flora, which normally doesn’t cause any problems or diseases. Sometimes though when the numbers get too low it can cause diseases or upper respiratory tract problems or infections (Todar, 2008-2012). Pneumonia caused by this pathogen has four stages. The first one is where the lungs fill with fluid. The second stage causes neutrophils and red blood cells to come to the area which are attracted by the pathogen. The third stage has the neutrophils stuffed into the alveoli in the lungs causing little bacteria to be left over. The fourth stage of this disease the remaining residue in the lungs are take out by the macrophages. Aside from these steps pneumonia follows, if the disease should persist further, it can get into the blood causing a systemic reaction resulting in the whole body being affected (Ballough). Some signs and symptoms of this disease are, “fever, malaise, cough, pleuritic chest pain, purulent or blood-tinged sputum” (Henry, 2013). Streptococcal pneumonia is spread through person-to-person contact through aerosol droplets affecting the respiratory tract causing it to get into the human body (Henry, 2013).
The human immune system is an amazing system that is constantly on the alert protecting us from
Most people who are exposed to the fungus experience symptoms, but do not get sick. The signs—fever, cough, and exhaustion—are difficult to distinguish from the flu, and can last for weeks to months. In people with weakened immune systems, the infection can cause more severe conditions such as meningitis or death. There is no vaccine for valley fever, and many in the general public (including the medical community) know very little about the illness. This lack of knowledge has allowed many milder cases to go undiagnosed, leading to underreporting.
Mumps is primarily a childhood disease, occurring most frequently between the ages of 5 to 9, although it was also known as a problem for soldiers during war because of the sanitary conditions and close proximity. For instance, in World War I only influenza and gonorrhea were more prevalent among the armies. It replicates inside the nose, throat, and regional lymph nodes. The virus incubates for about 14-18 days, and then a viremia occurs for about 3-5 days. During the viremia it can spread to the meninges, salivary glands, testes, ovaries and pancreas. Out of the infected population, 30 to 40% get swollen parotid salivary glands, with most of the rest being asymptomatic or having only respiratory problems. Around 60% of patients have asymptomatic meningitis, with up to 15% progressing to symptomatic. Encephalitis is also possible, occurring in around 5/100,000 cases. The encephalitis almost always results in some permanent hearing loss, and was historically the leading cause of hearing loss in children. Orchitis (testicular swelling) happens in up to 50% of post-pubertal males, with oophritis (ovarian swelling) happening in only 5% of women. Orchitis often results in testicular atrophy but very rarely in sterility.
While many forms of encephalitis exist, West Nile Virus was first isolated and identified in the West Nile District of Uganda in 1937. The virus, which was seemingly isolated to North Eastern Africa, became recognized as a cause of severe human meningoencephalitis (inflammation of the spinal cord and brain) in elderly patients during an outbreak in Israel in 1957. In addition to the human victims of this disease, the virus was found Egypt and France during 1960s to have fatal effects within horses. While this disease spread through Northern African and Southern Europe, 1999 marked the first appearance of West Nile Virus in North America, with encephalitis reported in both humans and horses.
Due to its tendency to be both a viral and bacterial disease, meningitis can prove difficult to treat. Its dual tendencies also mean that various methods are used to attack the disease. In order to treat meningitis, different aspects of the disease must be discovered first. The type of organism causing the infection, the age of the patient, and the extent of the infection must all be taken into account (WebMD, sec. 8). Any time meningitis is found, immediate treatment with antibiotics is required, and continuation of antibiotic treatment depends on whether a bacteria or a virus is causing th...
As an upcoming senior you will think that your senior year will be stress less. But that not the case it will be filled with work on top of work. During my senior year I didn't think senioritis was real until I have to actually do work I didn't feel like doing . Once I got to the second quarter I was completely check out and ready to graduate. As a senior myself I didn't do some of my homework, I was getting low test scores, and not coming to school. Senioritis is real and after the first quarter you will feel like it's no purpose. So it's important to stay motivated and avoid laziness.
However, not everyone develops cryptococcal meningitis. For the most part, when healthy individuals inhale these spores, they usually don’t get infected with cryptococcosis. On the other hand, individuals with an immunodeficiency due to an illness like HIV or AIDS, are highly susceptible to cryptococcosis. According to the Centers for Disease Control and Prevention, cryptococcosis is one of the common causes of deaths for people who are infected with HIV or AIDS. This infection is very prominent, especially in poor countries where treatment and prevention of cryptococcosis is unattainable.
Throughout history there have been very dangerous diseases that have been able to single handedly wipe out entire civilizations because there was nothing that we could do about it. Most of the time was because we did not quite understand what was actually happening. But thanks to all of the scientific advancements humans are able to live many more times than previous years. But that doesn’t meant that every human is healthy enough. This means that although we are less prone to die from some infectious diseases, we now have other risk for example not keeping up with a healthy diet is one of the many reasons why there are so many premature deaths. Now if you don’t get treated right away it can get worst the longer you get and sometimes it can also be fatal. One of those is Meningitis which is something very serious that if it doesn’t get treated it can lead to very serious complications in the long run or even death depending on the case. The reason why I chose this one was because when I was in high school I suffered from some...
Approximately one year ago in Kentucky, a man went to sleep thinking he might have caught a flu. The next day, he is rushed to the local hospital while coughing up chunks of lung tissue; within a few hours he experiences organ failure and lips into a coma. Over the next two days, two other patients come in with the same symptoms and die almost immediately. This epidemic that swept over this small area in Kentucky was an ultra resistant strain of staph infection known as MRSA, or methicillin-resistant Staphylococcus aureus (Eisler, 2013). MRSA and other species of resistant bacteria have arisen from the global overuse of antibiotics. Over the years, resistant strains of bacteria have become more and more difficult to fend of using common antibiotic treatments. If something is not done to stop antibiotic resistance, completely resistant strains of bacteria, which we will be unable to kill through use of antibiotics.
I was lead to Meningococcal meningitis which is a serious and potentially life threatening infection caused by the bacterium Neisseria meningitidis. The common symptoms of meningococcal meningitis are very similar of those five middle school children, high fever, stiff neck, confusion, nausea, vomiting, lethargy, and purpuric rash. Most cases of Meningococcal meningitis occur in children and teens. Meningococcal disease occurs more often in the seasons of winter or spring and spreads just like the flu. This disease passes from person to person through everyday activities such as risk living in close quarters, being in crowded areas for prolonged periods of time, sharing drinking glasses, water bottles, eating utensils, kissing, smoking or being exposed to smoke, staying out late and having irregular sleeping patterns. All these symptoms can weaken an individual immune
In this essay I will the experiment that a group of researchers conducted to determine which vaccine is more effective for preventing getting the flu. There were two types tested: a shot and a nasal spray. The numbers are as follows: 1000 participants were selected at random with 500 people getting the shot and 500 the nasal spray. Of the 500 people were treated with the shot, 80 developed the flu and 420 did not. People who were treated with the nasal spray, 120 people developed the flu and 380 did not. Level of significance was set at .05. Proportion of people who were treated with the shot who developed the flu = .16, and the proportion of the people who were treated with the nasal spray was .24. The calculated p value = .0008.
Dr. S.M. Shamim ul Moula, “Fighting Disease” May 9, 2001 African Networks for health research and development; retrieved Dec. 9, 2003 http://www.afronets.org/archive/200105/msg00035.php