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Essay on the marburg virus
Essay on the marburg virus
Essay on the marburg virus
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For my outbreak paper, I wanted to choose an existing disease that was extremely deadly and find possible scenarios of this disease’s transmission to the US. The disease I chose is called Marburg disease. I chose this disease because of its similarities to Ebola, which is also a very known deadly disease. Marburg has a high mortality rate, and fast progression form being healthy to being on your death bed. To create an outbreak for Marburg we need to understand the epidemiology of the disease including where it is from, how it moves, and if there are any treatments to prevent this disease. Unfortunately, Marburg was discovered accidently by trying to find a vaccine for polio.
Marburg was first dated in 1967 when the outbreak of hemorrhagic
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The incubation period for Marburg disease is 3 to 9 days, however the disease is similar to those of other infectious diseases such as typhoid or malaria making the disease hard to diagnose. Without proper testing equipment for the disease this means an infected person can die within a matter of days. Therefore, places like Uganda, Angola, and DRC have more cases of Marburg virus than any other countries. Tracking the virus down to its roots has been a difficult challenge for WHO doctors considering they are only called after the epidemic has …show more content…
We can now create a potential outbreak of Marburg Virus. Considering the transmission mode includes bodily fluids contact, our index cases include a couple scenarios. One scenarios include a person who is on a mission trip to Kenya and decided to visit a national Park like Mount Elgon. Tourist who come to these parks will adventure the caves which has fruit bats. As we learned earlier the African fruit bats are reservoirs for the Marburg Virus. There are report that date in 1980 and 1987 where people have visited the Kitum Cave in Kenya and contracted the virus and have died with 9 to 10 days after onset symptoms. In my outbreak I have two people who are on a mission trip and visit the Kitum Cave in Kenya. They visit the cave on their second to last day of their trip, and have came in contact of the fruit bats, not knowing the virus is within the bats. The two people then travel back to the US, and in my choice, they travel back to Indiana. When they do travel back to Indiana it has probably been two to three days since first contact of the bats and no signs of symptoms. This is where I think Marburg can be a deadly outbreak if we do not pay attention to details. The two people who visited the cave in Kenya then visit the caves in Indiana like Marengo within two days after getting back. If there are any bats in the cave what are the possibilities of the virus being
The exposure to the contaminated food happened during the Memorial Day service celebration, which was May 30th. According to the case study, onset of symptoms occurred from June 5th to June 28th. Therefore, the incubation period from this case ranged from seven days to thirty days. According to Heymann (2014), the incubation period for Typhoid fever ranges from 3 days to over 60 days, with the usual range from eight to fourteen days. A graph of the incubation period is provided in Figure
At first polio was a troubling prospect when it first reared its ugly head in the United States of America. In a noble effort to be rid of polio, America as a whole was to adopt stringent sanitation measures. Everywhere, especially the home was to be spotless and clean in order to try and prevent the contraction of polio. This coupled with the view that America as a western nation seemed impervious to such a lowly disease tried to assuage American fear of the disease. Despite the measures commonly adopted throughout the myriad of cities and towns, polio still managed to spread around the country and wreak havoc taking thousands of lives. An outbreak that ravaged America claimed nearly 27,000 lives in a terrible reckoning before it finally subsided. This and several other troubling outbreaks
[1, 4, 5, 9, 13] There have been no documented cases where a human has contracted the disease from another human. [4] It appears, based on field and lab data, that infection requires direct contact with the virus through means such as contact with infective bodily secretions, urine, or tissues. [12] It is unknown to scientists how the virus can be maintained in the bat populations and avoids extinction as the host species becomes immune to its presence. [14] The incubation period from time of infection to the onset of symptoms is about 5-14 days in experimentally induced animals [4] and 8-14 days in natural field cases.
The population of bats in the United States is facing a serious threat of extinction due to the outbreak of a deadly fungus called Deomyces destructans. The fungus is nicknamed White-Nose Syndrome, after the white fungus that typically appears on the infected bats noses and wings. Other signs and symptoms of White Nose Syndrome are white fungus on the ears and tail as well, bats flying during the day in the middle of winter, bats clustered near the entrance to a hibernacle or cave, and general abnormal behavior for a hibernating bat. Scientifically the fungus has been identified as, Deomyces destructans. The fungus itself causes damage to their connective tissues, muscles, and skin. It also can disrupt many of their physiological processes. Typically during a hibernation period bats will wake up on average every 10 to 20 days. An infected bat on the other hand will wake up every 3 to four days which causes them to burn up their fat stores twice as fast. When they wake up they are both dehydrated and hungry, around 90% of the bats actually die from starvation due to a lack of insects for food in the winter season. WNS is transmitted from bat to bat and that is why any contact between an infected bat from one cave population with a non-infected bat from another population has serious consequences.
Beside the Ebola Virus, there are many other lethal viruses that are similar to Ebola and have similar effects, and fatality rates. One virus that is somewhat discussed in the book, is the Marburg Virus.
Polio: An American Story describes a struggle to find a vaccine on polio through several researchers’ lives, and over the course of many years. The second thesis is the struggle between Salk and Sabin, two bitter rivals who had their own vaccine that they believed would cure polio. The author David M. Oshinsky, is describing how difficult it was to find the cure to a horrifying disease, which lasted from the Great Depression until the 1960’s. Oshinsky then writes about how foundations formed as fundraisers, to support polio research. Lastly, the author demonstrates how researchers were forced to back track on multiple occasions, to learn more about polio.
A common theme in the stories we have read is that glory, happiness, and success come in cycles (this theme is commonly represented as "the wheel of fortune"). This theme is present in the Arthurian tales, as well as in Beowulf. Each story tells a tale (or part of a tale) of a rise to glory, and the proceeding fall to disarray. The men always were the kings and warriors, but the women played different roles in the different
Paralytic poliomyelitis, "polio", held a reign of terror over this nation for decades. But unless you were born before 1955, polio may seem to be just another ephemeral disease that has been nonexistent for years. Those born before 1955 remember having a great fear of this horrible disease which crippled thousands of once active, healthy children. This disease had no cure and no identified causes, which made it all the more terrifying. People did everything that they had done in the past to prevent the spread of disease, such as quarantining areas, but these tactics never seemed to work. Polio could not be contained. Many people did not have the money to care for a family member with polio. This was one of the reasons the National Foundation for Infantile Paralysis was organized. The March of Dimes, the fund raiser headed by the National Foundation for Infantile Paralysis, raised thousands and thousands of dollars to help people care for their polio stricken family members and to aid in the cost of research for a vaccine that would put an end to this misery that affected the lives of so many people.
Piddock, Charles. "Winning the War on Polio." Current Health 2 10 2004: 25-7. ProQuest. Web. 17 Mar. 2014.
There is no vaccine to protect against it and, in the most severe cases, no cure. The population of Phoenix has grown by ten per cent in the past deca...
From 166 A.D. to 180 A.D., The Antonine Plague spread around Europe devastating many countries. This epidemic killed thousands per day and is also known as the modern-day name Smallpox. It is known as one of deadliest plagues around the world.
Today there are many infectious diseases around the world. An infectious disease is defined as an infection which can be caused by the entrance, development and manipulation of microorganisms in the body. Infections are classified as emerging and re-emerging. An emerging disease is a disease that has appeared in a population for the first time, or that it may have happened previously but is rapidly increasing in incident or geographic range. Whereas a re-emerging disease is a disease that has been present at a location in the past and was considered eradicated or controlled. Some emerging and re-emerging disease present today and in the past are, HIV and Aids, Ebola, Hendra Virus as emerging diseases and Malaria, Tuberculosis, and Cholera as re-emerging diseases. In this report the re-emerging disease ‘Poliomyelitis’ will be thoroughly investigated and from reliable research, the effectiveness of the management to prevent this disease in the world will be evaluated. Poliomyelitis, often called ‘polio’ or ‘infantile paralysis’ is an infectious disease caused by a virus. This dangerous infectious disease has been eradicated around the world except for three countries, Nigeria, Pakistan and Afghanistan.
The inevitable, but unpredictable, appearance of new infectious diseases has been recognized for millennia, well before the discovery of causative infectious agents. The ease of world travel and increased global independence has added layers of complexity to containing these infectious diseases that affect not only the health but the economic stability of societies (Morens et al., 2013).
In the 1960s, doctors in the United States predicted that infectious diseases were in decline. US surgeon Dr. William H. Stewart told the nation that it had already seen most of the frontiers in the field of contagious disease. Epidemiology seemed destined to become a scientific backwater (Karlen 1995, 3). Although people thought that this particular field was gradually dying, it wasn’t. A lot more of it was destined to come. By the late 1980s, it became clear that people’s initial belief of infectious diseases declining needed to be qualified, as a host of new diseases emerged to infect human beings (Smallman & Brown, 2011).With the current trends, the epidemics and pandemics we have faced have created a very chaotic and unreliable future for mankind. As of today, it has really been difficult to prevent global epidemics and pandemics. Although the cases may be different from one state to another, the challenges we all face are all interconnected in this globalized world.
For innumerable centuries, unrelenting strains of disease have ravaged society. From the polio epidemic in the twentieth century to the measles cases in the latter half of the century, such an adverse component of nature has taken the lives of many. In 1796, Edward Jenner discovered that exposure to cowpox could foster immunity against smallpox; through injecting the cowpox into another person’s arm, he founded the revolutionary concept known as a vaccination. While many attribute the eradication of various diseases to vaccines, many United States citizens are progressively beginning to oppose them. Many deludedly thought that measles had been completely terminated throughout the United States.