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Introduction to polio research essay
Introduction to polio research essay
Introduction to polio research essay
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In an interview with the American Academy of Achievement, Jonas Salk stated “Risks, I like to say, always pay off. You learn what to do, or what not to do.” As a man of science, Salk truly believes and lives these words every day. In his career he has surely taken many risks, chasing down new theories and ideas, only to lead to a dead end road. But one day, he stumbled upon an idea, and took a risk that left an impact on humanity forever. Not only has Jonas Salk left his stamp on the medical world with the development of the Polio vaccine, but his team continues to conduct groundbreaking research on some of today’s most deadly diseases.
Knowledge of Polio has seemingly decreased throughout the years, but there is no denying its terrifying impact on parents of the early 20th century. What many people are unaware of is the fact that Polio is caused by a virus that can be spread by simple person-to-person contact (History of Polio). Secretions from the nasal and oral cavities as well as contact with bodily waste (feces) lead to the spread of this virus. Upon contact with a “contaminated” person, the virus travels through the mouth, growing and reproducing new cells as it moves along the digestive tract (History of Polio). In the most severe cases of Polio, the virus exits the digestive organs and enters the bloodstream where it wages war with nerve cells. This results in throat and chest paralysis and possibly even death (History of Polio).
Scientists hypothesize that Polio has been affecting the human race for thousands of years (History of Polio). Proof of this came from an Egyptian picture that is believed to have been carved around 1400 BCE. This carving portrays a man with a “leg deformity similar to one caused by Polio” (His...
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...ion or desire, which was to be of some help to humankind, so to speak, in a larger sense…” (Salk). That ambition drove him to develop one of the greatest medical feats of all time and a build an unprecedented research facility. He had to take many risks and face many people who did not believe in him, but in the end, Jonas Salk accomplished more than anyone thought was possible. Long after his passing, Salk’s legacy of hard work, brilliant ideas, and simple compassion for the human race will live on. He has left his mark on history with his work and he has also placed himself into the future with the research that is being conducted every day in his name. It is only a matter of time before the Salk Institute comes out with another groundbreaking concept proving again what can happen when you mix a little courage, a lot of ambition, and a brilliant mind for science.
...m these advancements that are from human body parts. Instead, it is imperative to honor and preserve those who have made these interventions possible
At first polio was a troubling prospect when it first reared its ugly head in the United States of America. In a noble effort to be rid of polio, America as a whole was to adopt stringent sanitation measures. Everywhere, especially the home was to be spotless and clean in order to try and prevent the contraction of polio. This coupled with the view that America as a western nation seemed impervious to such a lowly disease tried to assuage American fear of the disease. Despite the measures commonly adopted throughout the myriad of cities and towns, polio still managed to spread around the country and wreak havoc taking thousands of lives. An outbreak that ravaged America claimed nearly 27,000 lives in a terrible reckoning before it finally subsided. This and several other troubling outbreaks
Moreover polio is a deadly disease that is caused by a highly contagious virus entering the nervous system in the brain or spinal cord causing temporary or permanent paralysis. There are three
Polio: An American Story describes a struggle to find a vaccine on polio through several researchers’ lives, and over the course of many years. The second thesis is the struggle between Salk and Sabin, two bitter rivals who had their own vaccine that they believed would cure polio. The author David M. Oshinsky, is describing how difficult it was to find the cure to a horrifying disease, which lasted from the Great Depression until the 1960’s. Oshinsky then writes about how foundations formed as fundraisers, to support polio research. Lastly, the author demonstrates how researchers were forced to back track on multiple occasions, to learn more about polio.
Jonas Salk, a virologist at the National Foundation for Infantile Paralysis (NFIP), used inactivated viruses (virus particles grown in culture and then killed by a form of heat) to create a polio vaccine. Salk drew blood from about two million children, which the NFIP checked for immunization. Through the collection of many HeLa cells and trial and error, the polio vaccine was ready in a year.... ... middle of paper ... ...
One of the other notable important advances was the “Conquest of Polio” this disease usually caused paralysis in the people who contracted the virus. Back then there...
In the United States there was a vicious enemy everyone feared. In the 1950s the United States was under attack by the ruthless Poliomyelitis virus. Americans lived in constant fear of their children contracting this horrible virus that left many children paralyzed. During the outbreaks in the 1950s foundations were created to fund research and create awareness to help find a way to eradicate the virus. Americans become focused on doing anything in their power to fight this virus off. Jonas Salk’s Exploration of Medicine and research led to the creation of the Polio vaccine that united the country, prevented further outbreaks, and introduced a new form of treatment which has limited the fatality of polio infections today.
Poliomyelitis is a virus that infects the nerves of the spinal cord, and brain which leads to paralysis and or death (Piddock, 2004). Poliomyelitis is best known today as Polio, and Infantile Paralysis. Tonsillectomy polio would take over the lymph nodes in order to spread the infection throughout the body, leading to muscle paralysis in the limbs, and in some cases respiratory failure. Bulbar polio was a much more severe form, it affected the top of the spinal cord which caused paralysis and inability to swallow fluids (Rifkind, 2005). Polio was transmitted through ingesting materials contaminated by the virus found in feces. Children would play in public swimming pools, and ingest the contaminated water which lead to infection (Piddock, 2004). After the person ingested the virus, it would travel their intestinal tract, and eventually compromise their lymph nodes, making them unable to fight off the virus. Symptoms were like those of the flu, such as fever, headache, and upset stomach. The minority of people were able to let the virus run its course and it would be passed through their feces like any other virus. Others weren’t so lucky, those with compromised immune systems were unable to fight off the virus, the lymph nodes would fail to protect the nervous system causing paralysis once it reached the spinal cord (Piddock, 2004). Poliomyelitis has since then been eliminated in the United States because of the polio vaccine that is giv...
Albert Sabin, the developer of the polio vaccine once said, “Without animal research, polio would still be claiming thousands of lives each year.” Polio is a deadly disease caused by a virus that spreads from person to person. This infectious disease renders the brain and spinal cord helpless while also ensuring a permanent case of paralysis to the victim. According to the Centers for Disease Control and Prevention, “…13,000 to 20,000 para-lytic cases were reported annually,” before the 18th century. After the introduction of the polio vaccine, “…a total of 2,525 paralytic cases were reported, compared with 61 in 1965.” This dramatic decrease in the prominence of the polio disease can only be attributed to the success of animal testing. Animal experimentation is used in the research of genetics, drug testing, biology, toxicity testing, cosmetic testing, and many other fields. Despite all of its beneficial traits, animal testing has been wildly controversial over the past decades because of its perceived unethical treatment towards animals. Although animal testing may be deemed unethical by many, it is a form of medical testing that has not only saved lives but has also greatly revolutionized the medical world.
Polio is a viral disease. It cripples thousands of people and infects even more every year. Even though millions are inoculated, and the polio disease has been successfully purged from hundreds of countries still thousands of people and developing countries are infected and still people are dying. According to the World Health Organization (WHO) polio affects the Central Nervous System, or CNS; by infesting the intestines and transmitting it into the nerves thought the blood vessels. There the virus spreads through the nerve cells to the brain stem or other motor units, while forever damaging the nerves.
Through the rise of technological advances in medicine, the vaccine has changed the world for the greater good of the human race. Making a great triumph and virtually eliminating an array of life-threatening diseases, from smallpox to diphtheria, thus adding approximately thirty years to many humans’ life spans. Although, a new complication has arisen, possibly linking neurological digression with this rise of new vaccines. Such a digression has forced parents to exempt their children from receiving vaccinations and brought forth mental anguish affecting the minds of many.
Polios epidemiology can be broken down into its basic definition, causation, and origin. According to the Healthline website “Polio…is a highly contagious disease caused by a virus that attacks the nervous system”. Polio is most commonly found in children younger than five but can also be found in adults as well.This viral disease is caused by the poliovirus that may come in one of three different forms; all of which are part of the enterovirus genus. This virus is spread through direct person-to-person contact, contact with infected mucus or phlegm from the nose or mouth, and contact with infected feces. There are three types of the polio disease which are subclinical infections, non-paralytic, and paralytic. Subclinical is the most common form and accounts for “approximately 95% of polio cases” (Healthline). Patience with this form of Polio may n...
Poliomyelitis, also known as Polio, is a highly contagious disease caused by a virus that attacks the nervous system. Most victims to this disease are younger than five years of age; they are more likely to get this disease than any other age group. Out of two hundred people infected with the polio disease one is most likely to result in paralysis. The Polio Virus has decreased greatly since the Polio Vaccine was developed. In 2010 a WHO (World Health Organization) pole reported only 1,352 cases worldwide. Since the Polio Vaccine was developed the U.S has not has a single Polio case since 1979.
When hygienic conditions were poor polio attacked infants. The disease was spread by contaminated water and contact with fecal contamination. Many infants died when the conditions were poor. But as conditions improved the virus spread differently. It was spread more through playmates and family members, the contamination came from the nose and throat. By the early 1950s, twenty-five percent of paralytic cases occurred in people 21 years old or older.
The procedures that will be the future of modern medicine currently fall into the realms of taboo and fictional. These procedures encompass every aspect of medical science, from exploration of the human body, curing diseases, to improving a person’s quality of life. Many of these procedures are not very well known, while a few have been in the spotlight. These procedures include cloning, nano-robotics, retro-viruses, and genetic manipulation via gene-specific medications. For any serious breakthroughs in modern medical science, we must embrace these new forms of treatment instead of shying away from them. Second, I’ll attempt to explain how these methods and procedures could benefit mankind.