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Hepatitis B is a viral liver disease that can cause mild to severe illness. The virus is one of several types of hepatitis viruses that cause inflammation and affect your liver's ability to function.
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Hepatitis B is a contagious liver infection caused by the hepatitis B virus. Hepatitis B can be acute or chronic. Every type of hepatitis can increase your risk of liver scarring and liver failure.
Hepatitis B infection may be either acute (short-lived) or chronic (long lasting):
• Acute hepatitis B infection may last less than six months. Normally your body will clear of the virus within a few months of infection. Hepatitis B often cause acute infection, but in some cases it might be chronic.
• If the infection lasts longer than
six months, it’s a chronic condition. This happens because your immune system is not strong enough to fight off the virus. Chronic hepatitis has a higher risk of serious illnesses such as cirrhosis and liver cancer. Young children – especially newborns or children younger than 5 – The younger you are when you have hepatitis B — particularly newborns or children younger than 5 — the higher your risk the infection becoming chronic. Chronic infection may go undetected for decades until a person becomes seriously ill from liver disease. Causes The hepatitis B virus (HBV) is transmitted from person to person through blood, semen or other body fluids. There are some common ways of HBV transmission, include: • Having unprotected sex with an infected person; • Sharing needles or syringes for drug use with an infected person; • Getting a tattoo from a shady parlor or from tools that are infected; • Sharing personal items, especially ones that can contact with blood such as razor, with an infected person; • Frequent contact with hepatitis B patients or taking care of infected person; Hepatitis B can transmit from pregnant moms to their baby during childbirth. However, most cases of hepatitis in newborn can be avoided by getting vaccination. Risk factors People with the factors may increase your risks at hepatitis B: • Sexual activities with multiple sex partners or with someone who's infected with HBV without using condom. • Use needles intravenouslywith an infected person. • Are a man who has sex with other men • Live with someone who has a chronic HBV infection • Are an infant born to an infected mother • Have a job that exposes you to human blood • Travel to regions with high infection rates of HBV, such as Africa, Central and Southeast Asia, and Eastern Europe • Share personal items like razors or toothbrushes with an infected person. Signs and symptoms There are some common signs and symptoms of hepatitis B, ranging from mild to severe, usually appear about one to four months after you've been infected, may include: • Abdominal pain; • Dark urine; • Fever; • Joint pain; • Loss of appetite; • Nausea and vomiting; • Weakness and fatigue; • Yellowing of your skin and the whites of your eyes (jaundice). Go to seek medical help if you have signs or symptoms of hepatitis B.If you know you've been exposed to hepatitis B, contact your doctor immediately. A preventive treatment may reduce your risk of infection if you receive the treatment within 24 hours of exposure to the virus.
This case study is about Abdul Chidiac, a 51 year old male, married with 4 children. He had a medical history of hypertension, hypercholesterolaemia and cirrhosis with two admissions in the last six months. He is a smoker and drinks beer, 5-6 bottles per day. As Carithers & McClain (2010) explained the patient’s medical history is another indicator of the risk for cirrhosis; the progression to cirrhosis is adaptable and may take time over weeks or many years. Cirrhosis is a liver disease characterized by permanent scarring of the liver that interferes with its normal functions including alcoholism. Most people who drink large amounts of alcohol cause harm to the liver in some way (Heidelbaugh & Bruderly, 2006). The cause of cirrhosis is not yet known, but the connection between cirrhosis and excessive alcohol ingestion is established (Jenkins & Johnson, 2010). Common causes of cirrhosis include: alcohol abuse, hepatitis B infection, hepatitis C infection and non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (Schuppan & Afdhal, 2008).
The common change is liver cell necrosis. It may be the form of an acute hepatitis or viral or alcoholic type. Alternatively there may be continuous liver cell damage as in metabolic disorders. When necrosis is massive as in severe viral or drug induced hepatitis, the areas of surviving parenchyma are assumed to undergo regeneration but fail to reproduce normal lobular or acinar architecture. The compressed necrotic zones then form the basis of the fibrous septa of the cirrhotic liver.
Hepatitis A is a usually short acting virus that occurs in humans and monkeys. It is caused by the Hepatovirus and the species is Hepatitis A Virus. There are two major ways in which Hepatitis A can be transmitted. One way is from person to person. This transmission occurs when the fecal matter of an infected person gets ingested by another person. Other ways Hepatitis A can be transmitted from person to person are through direct contact with an infected person, such as sexual contact, and sharing of needles for intravenous drug use. Hepatitis A can also be transmitted through coming in contact with contaminated food or water. Also foods that are uncooked or undercooked and have been contaminated with Hepatitis A can transmit the virus. (Bennett,
The Hepatitis B virus is a disease that affects the liver and results in swelling and loss of normal function in the liver. It is estimated that 350 million people are infected with Hepatitis B worldwide, with 50 million new cases diagnosed every year.(1) In the Unit...
As you know autoimmune diseases are your immune auto-generate antibodies against cells of your body. In here, I don’t tell physiology of autoimmune diseases but I will tell one of most autoimmune diseases that is immune fertility disease. Researchers at the University of Virginia Health System have found a new human protein, radical radial spoke protein 44 (RSP44) in July, 2007. RSP44 is antigen can be found in all men, residing in the sperm tail at the center of a structure known as the axoneme. Antigens can only stimulate antibody production when they come in contact with components of the blood. Under normal conditions, blood and sperm do not mix. Direct contact between the two is prevented by a cellular structure in the testes called
The Hepatitis A Virus affects many different systems within the body. The first being the digestive system and the gastrointestinal system because Hepatitis A causes an acute liver infection. The liver’s job is to process nutrients, filter the blood and toxin from your body, and fight infections. It produces important blood components, proteins, and bile which helps you digest food. The liver also stores glucose and vitamins. The Hepatitis A Virus causes inflammation that interrupts the liver’s ability to perform these vital functions. Having a healthy liver is crucial to your health because it supports many other body systems. For example, one function of the liver is to produce bile which is needed to break down fats. The body stores bile in the gallbladder and then sends it to the beginning section of the small intestine. Bile is then combined with other digestive
Hepatitis B Virus (HBV) is a double-stranded DNA virus in the Hepadnaviridae family. The infectious particle is 42nm in diameter, with a genome 3200 nucleotides long. It has an outer envelope and an icosahedral nucleocapsid, which contains viral DNA polymerase and has a diameter of 27nm. The envelope contains the HBV surface antigen (HBsAg); this is the molecule to which anti-HBV antibodies are directed. The non-infectious hepatitis B particles are composed of HBsAg only and come in the form of filaments and spheres. Their only likely purpose is binding up antibodies so the infectious particles can remain free. In humans HBV infects hepatocytes where it replicates within the nucleus, but can also be found in smooth muscle, bone marrow, kidneys, thyroid glands and other sites.
Pathogens are a type of microorganism that spreads viral and bacterial diseases. These diseases when present in human blood and body fluids are known as blood borne pathogens, and can spread from one person to another. (Worcester polytechnic institute) The most serious types of blood borne diseases are the hepatitis B virus (HBV) and hepatitis C virus (HCV), which can cause liver damage; and HIV (human immunodeficiency virus), which is responsible for causing AIDS (acquired immune deficiency syndrome). The blood borne pathogens can be spread when the blood or body fluids (semen, vaginal fluid, breast milk, and amniotic fluid) of an infected individual comes into contact with mucous membranes or an open sore or cut on the skin of another person. Mucus membranes are located in the eyes, nose, mouth, and other areas as well. ("Bloodborne pathogens: MedlinePlus Medical Encyclopedia") Two of the most common ways that pathogens are transmitted is through the exchange of fluids during sexual intercourse or by sharing infected IV needles. (Worcester polytechnic institute)
“Hepatitis is an inflammation of the liver.”("What Is Hepatitis?") There are three main types of hepatitis. These include hepatitis A, B, and C. These three types of hepatitis cause the most concern to medical staff due to their ability to spread and cause outbreaks. “Hepatitis A is a contagious liver disease that results from infection with the Hepatitis A virus.” (Centers for Disease Control and Prevention) It can range from acute to chronic. An individual can become infected with hepatitis A if they eat or drink food or water that has been contaminated with the virus. Some common “sources of vitamin A include shellfish, fruits, vegetables, ice and water”. (U.S. National Library of Medicine. “Hepatitis A.”) Hepatitis B is a serious, endemic, worldwide disease that can occur at any age. (Wilkins 45) The hepatitis B virus causes hepatitis B infection. Hepatitis B is transmitted though contact with the blood or bodily fluids of an infected person. (U.S. National Library of Medicine. “Hepatitis B.”) Hepatitis C...
There are four phases of Hepatitis B: infection, inflammation, fibrosis, and cirrhosis. In the first phase, HBV invades the liver and goes for the nucleus, where it releases contents of DNA and polymerase into the surroundings. It then maneuvers its way to the cell’s components and enzymes. The polymerase sways the liver cells to make segments of the HBV DNA from RNA. The virus makes liver cells create spare parts for other HBV viruses. Replicas are released from liver cell into the bloodstream, destroying host cell and infecting other healthy liver cells. This entire process can take a few hours to occur, but must continue multiple times for serious damage to occur. The second phase is inflammation. Inflammation is caused by lymphocytes trying to get rid of the virus, but they also release harmful chemicals that damage the cells and take part in damaging the liver. The third phase is fibrosis. Fibrosis is scar tissue caused by inflammation and chronic infection. According to Everson and Weinburg, (2002, pg. 64) “Only 5/10% of people develop chronic Hepatitis B from acute Hepa...
An estimated 242,251 Canadians, and 150 million people worldwide are chronically infected with the hepatitis C virus, and more than 350 000 people die every year from hepatitis C-related liver diseases.1 Hepatitis C can lead to other serious diseases, such as liver failure, death, etc. But without any vaccines available to prevent the contraction of the disease, it may be hard to avoid. Due to disease generally being asymptomatic many people are unaware that they have it, further spreading the disease because of a lack of prevention mechanisms. Hepatitis C when developed chronically can cause serious affects on the liver, which may even lead to death. With hepatitis C being such a serious disease, it is important that more people be tested for it so they can start treatment in the early stages of the disease, as well as be aware and informed, before it becomes a chronic infection leading to serious complications.
Hepatitis A is a virus or an infection that causes liver disease and inflammation of the liver. According to Centers for Disease and Prevention, hepatitis A is a self- limited disease that does not cause a chronic infection and it is rarely fatal. The virus is an infectious disease of the liver which cannot be transmitted by sneezing and coughing. It is usually transmitted from person to person through the feces or the mouth, from consuming contaminated food or water. Many people do not experience any symptoms of hepatitis A, but if someone was to get it, then the symptoms could last from 2 weeks to 6 weeks. The blood is tested to determine how the liver is functioning. The blood is usually taken from the vein in the arm and
Hepatitis A is caused by a virus that infected the liver cells which spread when people eat and drink something contaminated with feces. According to Mayo Clinic, the virus can spread by eating food when someone with the virus does not thoroughly wash their hands after using the restroom, drinking water that has been infected with feces, eating raw shellfish from water polluted with sewage, being in close contact with someone who is infected even if the person has no symptoms, and having sexual partners who have the virus. According to the Centers for Disease Control, a hep A vaccine is recommended for homosexual men, laboratory workers, people who use illegal drugs, people with chronic liver disease, and people who travel the world. Cases of hepatitis A are not distinct from other types of acute viral hepatitis. According to WHO, specific diagnosis are made by the detection of Hepatitis A Virus (HAV)-specific Immunoglobulin G (IgM) antibodies in the blood. Additional tests include reverse
What is hepatic cirrhosis? According to the medical dictionary hepatic cirrhosis is when scar tissue replaces the liver’s healthy tissue. This disease changes the structure of the liver and blood vessels that nurture it. It reduces the liver’s capability to produce proteins and process hormones, nutrients, medications, and poisons. Cirrhosis is an illness that gets worse over time and possibly can become life threatening. This serious illness is ranked as the ninth leading cause of death in the U.S. It is the third most common cause of death for adults between 45 and 65 years of age. It occurs in more than fifty percent of undernourished chronic alcoholics. Unfortunately it kills about 35,000 people per year. In other country’s such as Africa and Asia death from cirrhosis is usually caused by hepatitis B.
Hepatitis B, an infectious disease caused by the Hepatitis B virus (HBV, a DNA virus), was formerly called serum hepatitis, inoculation hepatitis and post-transfusion hepatitis. Infection with HBV may result in acute, fulminant or chronic hepatitis, sometimes even resulting in a chronic asymptomatic carrier state, apart from hepatocellular carcinoma and liver cirrhosis (Davis 179). The disease is transmitted when an individual comes in contact with infected blood or objects. It may also be transferred from an infected mother to her infant either during or after birth (Zuckerman et al. 211). Transmission may also occur by accidental inoculation from infected needles and hospital equipment, intravenous drug abuse, body piercing, tattooing, and mouth-mouth kissing (Zuckerman et al. 210). The risk of Hepatitis B is particularly high in individuals with multiple sex partners, and in homosexuals. The HBV virus occurs in morphologically different forms in the serum of infected individuals. HBV infection has an incubation period of about 75 days. Systemic symptoms of the disease include fatigue, fever, dyspepsia, arthralgia, malaise, and rash, while local symptoms include hepatomegaly, jaundice, dark urine, and pale stools (Davis 179; Zuckerman et al. 210).