Informative Essay On Smoking

796 Words2 Pages
bulb-icon

Recommended: Background on tobacco as a public health issue

Because you regularly smoke tobacco, which is one of the most avoidable risk factors for cancer, I wish to inform you of a research article that reveals progression toward understanding the mechanism by which tobacco smoke damages the genome, an organism’s complete set of DNA, and creates the mutations that ultimately cause cancer.
Tobacco smoking is linked to at least 17 different types of cancer such as lung cancer and oral cancer, and it leads to more than six million deaths per year. The smoke itself is made up of a large mixture of chemicals, at least 60 being carcinogens, substances that can lead to cancer. The way in which these substances cause cancer is by damaging the DNA which can lead to mutations in the cancer gene. The carcinogen …show more content…

Each base substitution was characterized using a 96-mutatino classification system that includes six substitutions together. In the study, 5243 cancer genome sequences of cancer that have an enhanced risk from smoking were examined to identify mutational signatures and methylation changes associated with tobacco smoking. The samples studied included 2490 from tobacco smokers and 1063 from non-smokers. Thus, the mutational consequences of smoking tobacco and refraining from smoking was able to be compared for lung, larynx, pharynx, oral cavity, esophageal, bladder, liver, cervical, kidney, and pancreatic …show more content…

Signatures 2, 4, 5, 13, and 16 showed significant contributions. Signature 4 is classified by C > A base mutations, and was found to likely be the consequence of misreplication of DNA damage from carcinogens. Signatures 2 and 13 are made up by C>T and C>G mutations, but they were only shown more in smokers than nonsmokers in lung cancer, while still being present in the other cancer types, unrelated to tobacco smoking. Signature 5 is characterized by mutations across all 96 subtypes of base substitution and is found in all cancer types. It occurs widespread in nonsmokers and in cancers unrelated to smoking; therefore, it can be concluded that it is probably not a direct consequence of misreplication of DNA damaged from carcinogens. Signature 16 is characterized by T>C mutations and was only increasingly detected in liver cancer for smokers versus nonsmokers, but its mechanism is

Show More
Related

  • Persuasive Essay On Vaping And Cigarettes

    877 Words  | 2 Pages

    Many actions have been taken on vaping and cigarettes, such as only allowing people over or at the age of eighteen to buy the product and putting warning labels on products. The serious issue is there needs to be action applied to the fact that these products can kill a human being. There is a wide variety of policies trying to be passed for vaping and cigarettes. A vaping regulation is trying to pass making all vape companies to carry products similar to products back when vaping firs started. This could cause the vaping market crash, making people lose money, and most important jobs. Some actions should be taken on tobacco products because of the risk of getting cancer in it is high.

    Read More

  • Argumentative Essay On Cigarettes

    1040 Words  | 3 Pages

    Experiencing the death of a loved one is never easy, especially when the cause is something self-inflicted, such as cigarettes. Imagine if that loved one was your parent or even worse, your own child. Now, imagine watching the demise and physical incapacities that transpire while you see them deteriorate right in front of you. Feel the anger that would coarse through your veins if you were to see an add that glamorized such deadly instruments, particularly once you realize that the areas being marketed are lower class. Cigarettes are legal killers that cripple many individuals and families alike. They are a highly addictive substance that benefit no one. I am against cigarettes in every capacity as I have dealt with the effects of it on a personal level. Cigarettes leave a distaste in the mouth literally and figuratively. I am also a firm believer that

    Read More

  • Tobacco In Systemic And Oral Health

    875 Words  | 2 Pages

    Various types of tobacco have a variety of negative outcomes. Extensive research has been done on inhaled tobacco smoking and has been proven to cause damage to many systemic functions of the body as well as lead to periodontal disease. The general public believes that smokeless tobacco is the safer choice but this may not be the correct assumption. Although there is evidence that smoking is associated with oral cancer, smokeless tobacco studies show this form of tobacco to be more strongly associated with oral cancer.1

    Read More

  • Persuasive Essay On Anti Smoking

    1650 Words  | 4 Pages

    “Cigarette is one of the leading cause of death in the World!” “Cigarette can cause lungs cancer!” “Cigarette is harmful and is bad for society!” These are the things that the society taught us ever since we are young. Everyone knows that cigarette is harmful for the human body, but why does the percentage of people smoking is still high and is increasing every year. Why does it is so hard for people to quit or not try cigarette in the first place, despite knowing the consequences of this small, innocent looking-yet-deadly roll of paper. Clearly, the effort of our society to prevent people from smoking is not effective. Recently, more and more anti-smoking campaigns were produced by different corporations, in order to join the race in tobacco

    Read More

  • Cigarettes Should be Illegal

    796 Words  | 2 Pages

    Smoking causes many other types of cancer, including cancers of the throat, mouth, nasal cavity, esophagus, stomach, pancreas, kidney, bladder, and cervix, and even leukemia has been found linked to smoking. Also, people who smoke are up to six times more likely to suffer a heart attack than nonsmokers, and the risk increases with the number of cigarettes smoked. Smoking also causes most cases of chronic obstructive lung disease. Also, approximately 49,400 deaths have been due to exposure to secondhand smoke. 3,000 nonsmoking adults die of diseases caused by exposure to second-hand smoke every year.

    Read More

  • Persuasive Essay On Banning Cigarettes

    658 Words  | 2 Pages

    Cigarettes are one of the most common killers known to mankind. Cigarettes kill about 6 million people every year, and that number isn’t going to go down in less we do something about it. Smoking in the twentieth century killed only 100 million people, whereas a billion could die in our century. There are several more reasons why we should ban cigarettes, and I am going list them.

    Read More

  • Cigarettes Should Be Made Illegal

    1584 Words  | 4 Pages

    Every year new medical reports are issued regarding the harmful effects of smoking cigarettes. Hundreds of thousands of people around the world die every year from diseases caused by smoking. Approximately one in two lifetime smokers will die from their habit. Half of these deaths will occur in middle age. The most common of the diseases caused by smoking is cancer, of course. Not only is it a cause of lung cancer, but cancer of the larynx, and the esophagus, and it contributes to the development of cancers of the bladder, pancreas, and kidney. Lung cancer comes from the tar in the cigarettes. The tar coats your lungs like soot in a chimney. It does not make a difference if a smoker changes to low-tar cigarettes because smokers will take a deeper puff to get the same affect as a regular cigarette. This causes them to draw the tar deeper into their lungs causing even more damage. The Surgeon General requires that every package of cigarettes has one of the following statements: SURGEON GENERAL’S WARNING: Smoking Causes Lung Cancer, Heart Disease, Emphysema, And May Complicate Pregnancy. SURGEON GENERAL’S WARNING: Cigarette Smoke Contains Carbon Monoxide. Despite these warnings most of the population is not aware of the other illnesses that can develop...

    Read More

  • Argumentative Essay On Electronic Cigarettes

    736 Words  | 2 Pages

    Nicotine is the chemical in tobacco that most impacts the brain and provides near instantaneous feelings of pleasure associated with smoking. People who smoke usually have ruff skin or other things that are wrong with them. Tar will also stain smoker’s fingers, their teeth, and collects in their lungs (Eshrick 32). Lung cancer is the most common cancers that most people have. Studies have proven that one out of every four people die from lung cancer, and ninety percent of cancer is caused by tobacco use (Eshrick 62). Bladder cancer may occur when smokers inhale some of the carcinogens in tobacco smoke are absorbed from the lungs and get into the blood, then filtered by the kidneys and concentrated into the urine. If the victim smokes more than twenty cigarettes a day it can double the risk of the most common type of kidney cancer (Eshrick 55). The last cancer is cervical cancer, the chemicals damage the cervix. There are cells in the lining of the cervix called Langerhans cells that specifically help fight against diseases. These cells do not work well in smokers (Eshrick

    Read More

  • Argumentative Essay: Why Cigarettes Should Not Be Legal

    1542 Words  | 4 Pages

    Most people would think that cigarette smoking can cause many health issues and diseases after looking at the ingredients used, and they are right. Periodontitis, Peptic ulcers, Erectile dysfunction, Chronic obstructive pulmonary disease, Cancer, and cardiovascular disease are just a few of the diseases that can be caused from smoking cigarettes. Smoking may also increase the chance of heart disease, stroke, atherosclerosis, and peripheral vascular disease. Tobacco has also been linked to Buerger 's disease, Oral disease and some infection throughout the body has also been caused by smoking

    Read More

  • Cancer Synthesis Essay

    459 Words  | 1 Pages

    An article from the American Cancer Society states that, “Cigarette smoking accounts for at least 30% of all cancer deaths.” (Source 1) Meaning that it has been proven, smoking puts you at huge health related risks. According to the American Cancer Society, “ Besides lung cancer, tobacco use also increases the risk for cancers of the mouth, lips, nose and sinuses, larynx, pharynx, esophagus, stomach, pancreas, kidney, bladder, uterus, cervix, colon/rectum, ovary, and acute myeloid leukemia.” After hearing this I believe it is safe to say tobacco use is one of the most preventable cancer carcinogens there are. Along with tobacco use, diet and physical activity is another one of the main preventable

    Read More

  • Persuasive Essay: The Dangers Of Smoking

    786 Words  | 2 Pages

    One of the biggest problems that people are faced with on a day-to-day basis is cigarette smoke. The sole cause for 480,000 deaths each year just in the United States is accredit to cigarettes(CDC). For a lot of the smokers the habit of smoking happens to assist them when under stress and dealing with issues that are unmanageable. Some smoke to appeal to their peers or simply because it “feels good.” Smoking one cigarette can lead to a major addiction. The effects of smoking hurt oneself and those amongst us. Smoking Kills as the ad portrays this revolver and cigarettes as the bullets, and also lists the side effects of smoking. Cigarettes causes cancer, increases the risk of you getting a stroke, highly addictive and causes a lot of health problems. Nearly 16

    Read More

  • How to quit smoking

    379 Words  | 1 Pages

    Cigarettes and cigarette smoke contain over 4,000 chemicals, including 43 known to cause cancer. Many of these chemicals are added in the processes of tobacco farming and cigarette production. The tobacco burns while a cigarette is smoked, exposing the smoker to these deadly chemicals, tars and gases

    Read More

  • Argumentative Essay On Smoking Cigarettes

    1146 Words  | 3 Pages

    Smoking cigarettes is a very deadly addiction that, unfortunately, 42.1 million adults in the United States and 6.4 million children have. The reason why so many people get addicted to cigarettes because of nicotine. Medicinenet.com says that nicotine is “Made by the tobacco plant or produced synthetically. Nicotine has powerful pharmacologic effects (including increased heart rate, heart stroke volume, and oxygen consumption by the heart muscle), as well as powerful psychodynamic effects (such as euphoria, increased alertness, and a sense of relaxation). Nicotine is also powerfully addictive.”

    Read More

  • Argumentative Essay On Smoking

    1198 Words  | 3 Pages

    Smoking cessation has major and immediate health benefits, including decreasing the risk of lung and other cancers, heart attack, stroke, and chronic lung disease. It is known that cigarette smoking causes 87 percent of lung cancer deaths and is responsible for most cancers of the larynx, oral cavity and pharynx, esophagus, and bladder. The risk of developing smoking-related cancers, as well as noncancerous diseases, increases with total lifetime exposure to cigarette smoke. Tobacco smoke contains thousands of chemical agents, including over 60 substances that are known to cause cancer. Smoking is the largest leading cause of death in the U.S.

    Read More

  • Smoking Essay

    832 Words  | 2 Pages

    In today’s generations most people know somebody that smokes cigarettes. Some of these smokers are coworkers, friends, family, or even themselves. Regardless of when they started smoking, it’s common knowledge that smoking is extremely harmful for the human body. According to the 2014 Surgeon General’s Report, “cigarette smoking has been linked to diseases of nearly all organs of the body.” Ironically most smokers fail to realize the gravity of the long term dangers they are exposing themselves to by smoking. Regardless of their choice, the long term uses of smoking cigarettes have been medically documented to cause lung damages, breathing issues, and heart complications.

    Read More

More about Informative Essay On Smoking

Open Document