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Short notes on influenza vaccine
E World Pandemic disease: Influenza of 1918-1920
E World Pandemic disease: Influenza of 1918-1920
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The influenza infection has a long history of having devastating effects on people worldwide but with the discovery and use of the influenza vaccine the fatally of the influenza infection decreased. The cause of the influenza infection is a virus. The virus enters the body via droplets coughed or sneezed and inhaled by a host (Bostock-Cox, 2013). Because the virus spreads via droplets it is very easily transmitted from person to person, which can lead to epidemics and even pandemics. In addition, the influenza virus is capable of mutating. The World Health Organization is responsible for tracking influenza virus changes and outbreaks around the world (Bostock-Cox, 2013). When referring to outbreaks in influenza infection the term epidemic is …show more content…
The most recent influenza pandemic that has affected the world occurred in 2009. In 2009 the “Swine flu” had a mortality rate of almost half a million people worldwide (Bostock-Cox, 2013). Unlike most yearly epidemics the “Swine flu” pandemic mostly affected persons under the age of 65. It was estimated that 87% of the deaths related to “Swine flu” occurred in persons under the age of 65 years old compared to yearly epidemics where 90% of deaths related to influenza occurred to persons 65 years and older (Bostock-Cox, 2013). Pandemics are an enormous public health risk, however yearly epidemics pose a similar public health risk worldwide. Due to the yearly public health risk that influenza epidemics cause, The World Health Organization recommends a mixture of viruses for a yearly vaccine for the northern hemisphere based on collected information about circulating virus strains throughout the year (Bostock-Cox, 2013). The yearly mixture is announced in February to allow for production and is distributed in September to providers to administer to the public (Bostock-Cox,
...influenza pandemic in one way or another; the use of quarantines were extremely prevalent among them. Also, the pandemic is directly responsible for the creation of many health organizations across the globe. The organizations help track and research illnesses across the globe. The CDC (Centers for Disease Control and Prevention) for example, strive to prevent epidemics and pandemics. They also provide a governing body with directives to follow in case an outbreak does occur, and if one shall occur the efforts of organizations across the globe will be crucial for its containment. It is amazing that with modern medicine and proper organization that influenza still manages to make its appearance across the globe annually.
However due to globalization, import and export viruses is more easily transmitted. Over the past century the global community especially Asian has been affected with new strains of the influenza virus. The changes in the virus can occur in two ways “antigenic drift” which are gradual changes in the virus over time. This change produces new strains that the antibody may not recognize. “Antigenic shift” On the other is a sudden change in the influenza virus which ‘’ results in a new influenza A subtype or a virus with a hemagglutinin or a hemagglutinin and neuraminidase combination that has emerged from an animal population,” as seen with H5N1 virus. This change leaves people defenseless against this new virus. (CDC, 2013) Currently there is no vaccine to combat all strains therefore “Planning and preparedness for implementing mitigation strategies during a pandemic requires participation by all levels o...
Current influenza vaccines are about 70% to 90% effective in preventing influenza in healthy adults. Since the vaccines are made of dead fragments of influenza viruses, they cannot cause influenza. The strains of influenza that circulate change every year and therefore, it is necessary to make a new influenza vaccine annually. After vaccination, the body's immune system produces antib... ... middle of paper ... ...
One of the most virulent strains of influenza in history ravaged the world and decimated the populations around the world. Present during World War I, the 1918 strain of pandemic influenza found many opportunities to spread through the war. At the time, science wasn’t advanced enough to study the virus, much less find a cure; medical personnel were helpless when it came to fighting the disease, and so the flu went on to infect millions and kill at a rate 25 times higher than the standard.
It is necessary in order to understand Avian Flu's impacts on society to first understand what H5N1 influenza is. Like any virus, influenza viruses cannot reproduce on their own the way bacteria can. Technically, viruses aren’t even alive because in order for them to reproduce, they must take over the living cell of another organism. This makes all viral diseases notoriously hard to cure because modern research has yet to reveal a medication or procedure that can kill a virus without killing its host. The best medications that we currently have available to treat viruses can only prevent the virus fro...
Influenza is a major public health problem which has outbreaks all over the world. Resulting in considerable sickness and death rates. Furthermore, it is a highly infectious airborne disease and is caused by the influenza virus. Influenza is transmitted easily from one person to another person, which has a great impact on society. When a member of society becomes sick, it is more prone to spread to other people.
Influenza is very contagious and spreads rapidly from person to person. Influenza causes worldwide yearly epidemics. According to World Health organization Influenza affects 5-15% world’s population and resulting in 500,000 deaths yearly. Ottenberg stated that, in United States, an average of 200,000 were hospitalized and 36,000 died each year from influenza complications. Influenza is the sixth leading cause of death among US adults and is related to 1 in 20 death in persons older than 65 years. Disease control and prevention estimates indicate that infections like H1N1 which is one of the types of influenza, have resulted in an estimated 42 to 86 million cases and 8520 to 17620 deaths. As I mentioned earlier that infections like influenza are very contagious, they can spread easily from hcw to Patient and back to hcw. The most efficient and effective method of preventing influenza infection is vaccination(The best way to prevent influenza is with annual vaccination).(Sullivan,2010) (Gregory,Tosh &Jacobson, 2005). Motivated by a desire to actively avoid illness Influenza may increase the risk for death in people with existing heart, lung, or circulation disorders. In fact, the higher than average number of winter deaths in people with heart disease may be due only to the occurrence of influenza during those months.Vaccination provides immunity to fight against infection.To increase resistance to harm by modifying the environment to minimize preventable illness (NEED TO CHANGE WORDING)
Throughout 1918 and 1919, influenza spread quickly in three waves killing an estimated 50 million to 100 million people worldwide. With the best-recorded first case having occurred in Fort Riley, the contagious flu spread across military camps around the United States. Due to the world war, the influenza virus was brought over to Europe where it infected people in nearly every country. This disease would end up causing one of the greatest pandemics in human history, but would also catalyze great advancements in science and medicine.
The influenza pandemic of 1918-1919 killed more people than the Great War, known today as World War I (WWI), at somewhere between twenty and forty million people. (1) Influenza is a virus that appeared in 1918 and caused a pandemic. It made an enormous impact that is still significant to the world today. It has pushed scientists to make advancements in the medicine and vaccination industry that continue to grow each and every day. Influenza may be a horrible thing, but without it we wouldn’t be where we are today.
Influenza is defined as an acute, commonly epidemic disease, occurring in several forms, caused by numerous rapidly mutating viral strains and characterized by respiratory symptoms and general prostration. Spanish flu was more than just a normal epidemic, it was a pandemic. Epidemics affect many people at the same time in areas where the disease doesn’t normally occur. A pandemic is an epidemic on a national, international, or global scale. The Spanish flu was different from the seasonal flu in one especially frightening way, there was an unusually high death rate among healthy adults aged 15 to 34 and lowered the life expectancy by more than ten years. Such a high death rate has not occurred in this age group in and epidemic prior to or since the Spanish flu pandemic of 1918. (Tumpey, 2005)
“Selecting the Viruses in the Seasonal Influenza (Flu) Vaccine.” Centers for Disease Control and Prevention. USA.gov, 9 March 2011. Web. 19 Jan. 2010
Vaccines save us from being infected with viruses. They save approximately 2.5 million people from death every year. However, while they help save lives, vaccines still have both minor and severe side effects. This can result in nausea, severe sickness, and in rare cases, death. Every year, 3,000 to 4,500 people in the United States are hospitalized due to vaccine side effects. It is extremely important for all communities to be informed about the side effects of vaccines and what causes them. Also, the Centers for Disease Control and Prevention say that the influenza vaccine is only 48% effective, due to constant mutation of the virus (Scutti, 2017). This means, the influenza vaccine does not work on all
Currently, one cannot explore the news without coming across the topic of the swine flu, scientifically known as H1N1. Swine flu is a respiratory infection derived from the influenza virus. The virus contains genetic materials from human, swine, and avian flu viruses. It was first identified in spring 2009, and since then has spread rapidly across the globe. The infection’s spread has been verified as a global pandemic by the World Health Organization. As soon as the swine flu virus was isolated, scientists quickly developed a swine flu vaccine. Four vaccines have been approved by the FDA for the prevention of the swine flu. The vaccines will be ready for distribution in October 2009. Now the question is: To vaccinate, or not to vaccinate? Millions of people are now preparing to answer this question.
The swine influenza or swine flu is a respiratory disease in pigs that is caused by the type A influenza viruses. These viruses are referred to as swine flu viruses but scientifically the main virus is called the swine triple reassortant (tr) H1N1 influenza virus. When the viruses infect humans they are called variant viruses. This infection has been caused in humans mainly by the H1N1v virus in the United States. The H1N1 virus originates in animals due to improper conditions and the food they ingest. The virus stays in latency form, thus harmless to the respective animal. The longer the animals survive the more likely the virus is to develop and strengthen making it immune to vaccines. The virus reproduced through the lytic cycle. The virus injects its own nucleic acids into a host cell and then they form a circle in the center of the cell. Rather than copying its own nucleic acids, the cell will copy the viral acids. The copies of viral acids then organize themselves as viruses inside of the cell. The membrane will eventually split leaving the viruses free to infect other cells.
According to the Swine flu investigation team on April 15 and April 17, 2009, novel swine-origin influenza A (H1N1) virus (S-OIV) was isolated from two epidemiologically unlinked patients in the United States. The same strain was identified in other countries such as Mexico and Canada. In the United States 60% of patients were 18 years of age or younger suggesting that the younger population was more susceptible to the transmission of S-OIV or the possibility that the older population had developed a small amount of antibodies from the 1976 swine influenza vaccine (H1N1). 18% of the patients had recently traveled to Mexico, and 16% were identified from school outbreaks. (France, Jackson & Schrag, 2010) The most common presenting symptoms were fever (94% of patients), cough (92%), and sore throat (66%); 25% of patients had diarrhea, and 25% were experiencing emesis. Therefore, the criteria characterizing the S-OIV infection are comparable to the ...