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The effects of tuberculosis
Introduction to mycobacterium tuberculosis
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Tuberculosis (TB) is a transmittable and often severe airborne disease, an infection caused by a bacteria known as Mycobacterium tuberculosis (Mtb). TB usually affects the lungs, but it also can affect any other organ of the body. It is usually treatable with a scheduled routine of medicine taken for 6 months to 2 years, the length of treatment is conditional on the type and severity of the infection ( WHO. October 2015). This usually happens when a person breathes in the contaminated air, in which inhaled TB bacteria make their way to the lungs. The immune system cannot stop the bacteria from growing and spreading after the initial infection.
People that immune systems that are weaker, tend to be at a greater risk for developing TB. When they breathe in TB bacteria, the bacteria settles in their lungs and start growing because their immune systems cannot fight the bacteria. Tuberculosis can develop within days or weeks after being exposed. However, it is possible for it to develop months or maybe even years after being infected, at a time when the immune system becomes weak for other reasons and is no longer able to fight the bacteria. (Bennett, Raphael 2010)
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Within the lungs TB moves through the blood to settle in different parts of the body. Some symptoms of TB includes coughing, loss of weight and appetite, fever, chills and night sweats as well as symptoms from the specific organ or system that has been affected. Tuberculosis usually can be cured with speedy and correct treatment, but it remains a key cause of death and disability, particularly among people infected with HIV (World Health Organization
There are two types of Tuberculosis: Latent TB infection and TB disease. Latent TB is the infection that occurs in a patient who has not been previously exposed to the disease and has not been sensitized. TB Disease occurs when the immune system is not able to fend off the disease and the bacteria become active and multiply. Of patients who contract the disease, approximately 5% of them actually develop TB to the full extent.
Tuberculosis is marked by symptoms such as a hollow cough, an emaciated body, nightly weats and daily intermittent fevers. Tuberculosis was common amongst working classes because it was contracted through pestilent, infected air, manifesting itself in places surrounded by swampy land. Geography plays an important role in the transmission of tuberculosis. The working classes could not afford to live in areas that were free of the epidemic. The upper classes did contract consumption, although they sought the medicine of the day which often brought them to health. The most popular remedy was a sea voyage in a warm climate, but also pure air and the most nutritious food were encouraged. Accordi...
Tuberculosis or TB is an airborn infection caused by inhaled droplets that contain mycobacterium tuberculosis. When infected, the body will initiate a cell-mediated hypersensitivity response which leads to formation of lesion or cavity and positive reaction to tuberculin skin test (Kaufman, 2011). People who have been infected with mycobacteria will have a positive skin test, but only ones who have active TB will show signs and symtoms. Basic signs and symptoms include low grade fever, cough with hemoptysis, and tachypnea. They may also show pleuristic chest pain, dyspnea, progressive weight loss, fatigue and malaise (Porth, 2011).
Drug resistance in mycobacterium tuberculosis (TB) has become a severe global health threat. The fight against TB is now facing major challenges due to the appearance of Multi-Drug Resistant Tuberculosis (MDR-TB) and more recently, the virtually untreatable Extensively Drug Resistant Tuberculosis (XDR-TB). MDR-TB are strains that are resistant to both top first-line drugs, Isoniazid and Rifampin, while XDR-TB are MDR-TB strains that are also resistant to any fluoroquinolone and one or more of 3 injectable drugs. With this new resistance, there emerges a great need to find new drugs that are as effective, yet bypass the problem of resistance. One method of research is to find new vulnerabilities of tuberculosis to use as new target sites of drugs. This method is highly expensive (Scheffler, Colmer, Tynan, Demain, & Gullo, 2013), and requires intense and lengthy research just to implicate the new target site. An alternative is to develop new drugs that work on the same already known target as the first-line drugs, but by a different mechanism, thereby bypassing the resistance of the TB to the drug.
TB germs enter the body, the immune system builds a wall around them. While TB
This report will discuss how liver cancer affects the liver. I will discuss the how liver cancer affects the normal operation of the liver, what causes liver cancer, how this cancer can be detected and how this cancer can be treated. I will conclude with a discussion of how common liver cancer is.
The name Tuberculosis derives from ‘tubercles’, which are present in the lymph nodes of affected animals.
Tuberculosis is transmitted by inhalation of aerosols containing the tubercle bacilli. The required inoculum size for infection is usually high, but easily occurs with exposure to a patient who is currently infected. The products of dried aerosols, droplet nuclei, are particularly infectious because they remain in the air for an extended time, and upon inhalation easily move to the alveoli. The severe damage related to infection is caused by the reaction of the host. The tuberculosis infection has two phases, primary and secondary.
American Lung Association. “Who Get’s It.” Tuberculosis (TB.) On-line. Internet. 1 March 2001. Available: <a href="http://www.lungusa.org/diseases/lungtb.html">http://www.lungusa.org/diseases/lungtb.html
The immune system is a fascinating structure it defends the body against foreign invaders like bacteria, viruses and parasites. There are two primary forms that make up the immune system they are, innate and adaptive systems. Both the innate and adaptive system plays a large role in the immune system. The innate is the primary system to defend against foreign materials and the adaptive is the secondary system that responds to specific issues.
TB is a contagious disease. Like the common cold, it spreads through the air. A person acquires a tuberculosis infection by inhaling tiny droplets of moisture contaminated with the Mycobacterium Tuberculosis bacteria. The source of these droplets is frequently from infectious individuals who expel thousands of water droplets into the air every time they cough, sneeze, talk or spit. A person needs only to inhale a small number of these to be infected. The most common places for becoming infected with TB are right in your own home, or your workplace. Often the source of the infection is unknown since the initial infection may have occurred several years ago.
Active tuberculosis only develops in about 10% of infected persons, remaining dormant in the rest; although the latent infection may later progress to active disease years later, especially in immune-compromised individuals. 9 Infection by MTBC may involve any organ of the body, but clinical presentation is most common in the lungs (pulmonary TB). General symptoms include fever, loss of appetite, weight loss, fatigue and severe cough with bloody sputum (hemoptysis) which may lead to death if untreated. 10 Mortality rates without treatment are high: in a study of natural history of TB in HIV-negative patients, 70% died within 10 years. 11 Tuberculosis remains a major health problem in the world...
Untreated tuberculosis patients can pass the disease by coughing or sneezing, this fills the air with bacteria containing Mycobacterium. Inhaling these unhealthy bacteria a person can be infected with tuberculosis. “This causes the parasite to multiply in the blood, causing headaches, fever, weakness, pain in the joints, and stiffness.” (World Health Organization, 2014) People who become ill might not demonstrate signs of illness right away. Nevertheless, medication is available for tuberculosis, though this can take six to nine months and sometimes longer to be treated during the course of taking the
Why is the human body full of viruses and other bacteria? Most foods we eat even the air we breath is full of nasty bacteria floating around in them. Even Medicines are full of viruses that are reconstructed to be antibodies, helping the body fight off illnesses. So, what happens when the body has to deal with the same viruses over a long period of time? Well, It is believed that a superbug is formed. A superbug is a mutated stronger version of the main virus that has a immunity to the medicine made to kill it. The human body makes antibodies on its own at a sluggish rate. Therefore, medicines with antibodies are made to speed up the process of producing antibodies.
Tuberculosis has plagued mankind for a long time. This disease, which was previously believed to be eradicated, has once again shown up and begun attacking the lives of many humans. Tuberculosis infects a third of the population and kills a fraction of them. Many approaches have been used including different varieties of infection control, bodily defenses, and treatments to try to protect humans from tuberculosis. The best way to prevent tuberculosis infections is to contain the source of tuberculosis. The most common source of tuberculosis infection is from infected humans. By diagnosing, containing, and treating people with latent tuberculosis before they get active, contagious tuberculosis, tuberculosis can be quickly contained. Once someone has been diagnosed with TB, they should be placed under isolation.