Have you noticed that influenza has been in a bit of an uproar in the world for the last few past years? When news spread out about the two teams of researchers had purposefully tweaked H5N1 bird flu in the lab to potentially make it more transmissible among human beings. Those two scientists Yoshihiro Kawaoka and Ron Fouchier had with the expectation of swift publication. The National Science Advisory Board for Biosecurity (NSABB) did something unprecedented: they ruled that the two papers should be censored if published, that they should be scrubbed of the complete methods and viral mutations that the researchers studied, in order to head off the risk that terror groups could use the information to craft a deadly bioweapon. If you didn’t …show more content…
know H5N1 is strain of the avian flu, it very dangerous especially through the way it is transmitted. Statistic of the current deaths also shows the possible pandemic rising in the future. There a higher percent chance that the flu will not become a deadly killer disease. And there many possibilities and still no one can completely sure of the future result. H5N1 also known as A(H5N1) it a virus which can cause illness in humans and many other animal species. A bird-adapted strain of Highly Pathogenic Avian Influenza (H5N1) is the highly pathogenic cause agent of the H5N1 flu, commonly known as the typical bird flu. This strain is in many bird populations and is spreading globally after first appearing in Asia. It is epizootic and panzootic, which is killing tens of millions of birds and still spreading through hundreds of millions of other birds. H5N1 flu is probably one of the most feared possible outbreaks in today’s world because of its likelihood to mutate. This particular type of strain mutates, allowing human to human transmission easy, this immense chance for a world widespread. This can also leave the earth atmosphere with the possibility of humans not being able to resist these diseases. This virus has been evolving more and more each day. “Antigenicity” is the ability of the immune system to resist the antigen, and is continue changing constantly. “In addition to this is the factor that scares people the most about the H5N1 virus. If it mutates, it will be harder for people to resist the virus. There are two known types of the virus in the world. These types are geographically isolated from one another, though both remain within Asia. One type is been situated in Thailand and other countries, while the other strain is located within China and japan. There is a possible third type of strain which exists in the northern parts of Vietnam and Thailand that is thought to be even more dangerous considering its evolution rate and its current array of antigens. But still scientists are unsure about the true significance of these separate types of strains, although the virus a higher chance to mutate. Even the common belief is that these mutations are conducive to the generation of an indestructible virus. The only way to be sick with the H5N1 flu virus is to have close contact with the birds that are infected with flu.
It can only be transmitted through feces, mucus or saliva. Birds that are infected with the virus and three or more touches through the facial openings, there is a 90% or more chance that whoever touched it will become infected with H5N1 flu. But, if humans take safety precautions, such as hand washing it should be easy to prevent the spread of this virus. Human to human transmission has only been seen two cases, both outside the United States, one in Indonesia and the other in Thailand. This disease only been transmitted through these people because they did not take safety precaution which was needed to protect themselves. The case in Indonesia was a male poultry worker who was infected with H5N1 flu. He was then contaminated with the rest of his family with whom he close contact with. However the case in Thailand was very similar he was a poultry worker as well, who became very sick after been infected with H5N1 virus. He also infected other family members through close contact. There has similar mutation which led up to dreadful Spanish flu in 1918 that concerns the World Health Organization (WHO) that it could happen again. There is a 99% chance that if the virus mutate, it will be a lot more deadly than the flu of 1918. There have been several reasons to lethality, one of the reasons is that the world has more highly populated and city has become denser. …show more content…
If an outbreak occurs in the city area the possibility of a huge widespread is extremely high. Modern technology has been greatly facilitated worldwide, which has consequently allowed disease to travel too easily. H5N1 has become more deadly to both birds and humans than the 1918 Spanish Flu was, the speed and virulence which this virus might spread could be very devastating. Yet, under the circumstances that the H5N1 virus does mutate, it will also lose a sufficient amount of force. Because during it process of mutation, it have to sacrifice it killing in order to be able to mutate in a way. The gene that has control of its ability to transmit is closely related to the genes controlling the force. Currently, H5N1 does not pose a major threat to society, but about 300 people has become sick from the virus worldwide and almost 160 birds die each year.
In 2005, 10% of the bar-headed geese were killed by H5N1 flu. However, most of the birds that had been infected during these small outbreaks were located in a small decay poultry farms in central and southeastern Asia. Many of the bar-headed geese died, and the species is still trying to exist. They’re also not being eaten but humans, so therefore, the geese that are sick will not infect humans. The benefits of these countries are adopting more measures to contain this dangerous flu, such as examining the poultry farms more carefully and making sure they birds are living an a sanitary environment. The H5N1 flu has never been found in the United States. Nearly all of the bird in the United States has been vaccinated and not one bird has been recorded to have been infected or sick with H5N1 flu. Even though there is the possibility that the infected birds could and probably have migrate from Asia to Alaska, it is not thought to be a major problem for the human population since the migration of the birds are not commonly used as food. With human contact would be scarce with these birds. Many wild birds, such as geese, ducks, and hawks, will likely to be the most affected in this scenario. These wild birds almost never come in close contact with humans and the only plausible way to contract the H5N1 flu from a wild bird is
touch an infected one and not take sanitizing measure afterwards. One of the major worry is the food supply. H5N1 virus does appear in our food supply through a mistake, the USDA has devised a plan that will stop the spread of the virus. The method will be to kill and the bird that were infected with this virus plus all the other birds living near the vicinity. Even if the case does go undetected, if the virus is cook thoroughly the virus will be killed. But, however if the H5N1 virus does start to infect humans, the result will be vary appalling. Thus far, about 36 different cases of H5N1 flu have been recorded. Out of those cases, only 18 have been fatal. Although the virus will lose its potency after the mutation, scientist has even speculated that in a worst case scenario, 48% of those infected will die even after the mutation. Although this is very unlikely, this is considered as a possibility. More probable outcome is that the virus will mutate into a very transmissible virus, but also undergo another mutation, allowing it to regain its potency before the mutation. Therefore, a very possibility is that the virus will not mutate at all, only affecting the virus population. The H5N1 strain of the influenza has been a major concern to society. Despite the fact that it is a problem to be thinking of, the virus may not be as lethal as it is thought to be. The possibility that this virus will cause a pandemic is very slim and most governments are readily prepared. Even if things take a turn for the worse and the virus stays lethal and mutates into a deadly form, life on earth may not completely end because there may be certain individuals in each species who can resist the virus. The H5N1 virus should be of a small concern but in truth, there is not much that separates its more lethal than most other diseases. In 1997 the H5N1 virus jumped the species barrier from birds to human and chicken in china. This caused china to be very alarmed about this new virus, not only china but the whole world was threatened and worried because of how it had change the species barrier so fast. The virus begins to spread very rapidly and killed most of its human and animal victims. This cause many of the poultry chickens and birds in the surrounding areas to be killed, thousands of chickens killed because the H5N1 virus didn’t affect chickens the way it affected humans. The factories and business that produced the chicken were force to close down because they lost a lot of business. This virus really didn’t disappear completely after the accident; it took almost 4 years break then appeared in other countries in 2003. Many people died of this disease mainly because there were no symptoms that could tell that the poultry was infected. The virus reappeared in China, Cambodia and Indonesia in the month of May 2005. This was the first time ever the virus appeared in three areas in the same month and year. The spread of the virus worried other because they feared where the virus would hit next. The outbreaks lead to killings of many poultry and to the containment of traveling between the three countries that were affected. The spread of the H5N1 virus, its symptoms and how it affected humans alarmed many nations this is where the rumor of a pandemic started. There is different type of strands of H5N1 affects birds and humans differently. The most harmful strand to humans is not physically apparent in poultry and birds, but there certain type of strands of the H5N1 virus that are deadly to poultry. One of the strands that affect birds results in a slow painful death. The first signs are Respiratory Illness, over a couple of days; the respiratory illness soon leads to Intestinal Illness and Neurological Illness. The symptoms in humans are similar but they do have some variations. In humans many times the H5N1 virus is often mistaken for Pneumonia, the symptoms of Pneumonia and the H5N1 disease are very similar; the symptoms in both illnesses include severe shaking with chills, a high fever and headache, and a persistent cough. The incubation period in humans is about 2 to 4 days. The H5N1 virus is very transmissible; most of the incidents were caused by some type of transmission, blood or even eating poultry infected by the virus.
This summer we had an opportunity to dive into the world of bioweapons, through Richard Preston’s novel The Demon in the Freezer. His book explored the colorful world of smallpox and its use as a biological weapon. Earlier this week we were graced with this authors present for an ACES event. He discussed some of the found topics in his book such as animal testing, what small pox is, and even its eradication. One of the great things we had the chance of vocalizing were our many opinions on the gloom associated with this intriguing disease.
Other ways hepatitis A can be transmitted from person to person are through direct contact with an infected person, such as sexual contact, and sharing of needles for intravenous drug use. Hepatitis A can also be transmitted by coming in contact with contaminated food or water. Also, foods that are uncooked or undercooked and have been contaminated with Hepatitis A can transmit the virus. Bennett, A. J.,2016; World Health Organization, 2017) Hepatitis A can affect a person of any age group.
It has not taken human to human transmission yet, that we know of. So far all cases of the virus result from people coming into close contact with bird blood or droppings. If the transmission of the virus does take human to human form, it could unleash a global pandemic. This is the first time in history that humans have been able to prepare themselves for an epidemic. The bird flu virus travels with migrating birds.
However due to globalization, import and export viruses is more easily transmitted. Over the past century the global community especially Asian has been affected with new strains of the influenza virus. The changes in the virus can occur in two ways “antigenic drift” which are gradual changes in the virus over time. This change produces new strains that the antibody may not recognize. “Antigenic shift” On the other is a sudden change in the influenza virus which ‘’ results in a new influenza A subtype or a virus with a hemagglutinin or a hemagglutinin and neuraminidase combination that has emerged from an animal population,” as seen with H5N1 virus. This change leaves people defenseless against this new virus. (CDC, 2013) Currently there is no vaccine to combat all strains therefore “Planning and preparedness for implementing mitigation strategies during a pandemic requires participation by all levels o...
A few years before 1918, in the height of the First World War, a calamity occurred that stripped the globe of at least 50 million lives. (Taubenberger, 1918) This calamity was not the death toll of the war; albeit, some individuals may argue the globalization associated with the First World War perpetuated the persistence of this calamity. This calamity was referred to the Spanish Flu of 1918, but calling this devastating pestilence the “Spanish Flu” may be a historical inaccuracy, as research and historians suggest that the likelihood of this disease originating in Spain seams greatly improbable. Despite it’s misnomer, the Spanish Flu, or its virus name H1N1, still swept across the globe passing from human to human by exhaled drops of water that contained a deadly strand of RNA wrapped with a protein casing. Individuals who were unfortunate enough to come in contact with the contents of the protein casing generally developed severe respiratory inflammation, as the Immune system’s own response towards the infected lung cells would destroy much of the lungs, thus causing the lungs to flood with fluids. Due to this flooding, pneumonia was a common cause of death for those infected with Spanish Flu. Due its genetic similarity with Avian Flu, the Spanish Flu is thought to be descended from Avian Flu which is commonly known as “Bird Flu.” (Billings,1997) The Spanish Flu of 1918 has had a larger impact in terms of global significance than any other disease has had because it was the most deadly, easily transmitted across the entire globe, and occurred in an ideal time period for a disease to happen.
Silverstein, Arthur M. Pure Politics and Impure Science: The Swine Flu Affair. Baltimore and London: The John Hopkins University Press, 1981.
One of the most virulent strains of influenza in history ravaged the world and decimated the populations around the world. Present during World War I, the 1918 strain of pandemic influenza found many opportunities to spread through the war. At the time, science wasn’t advanced enough to study the virus, much less find a cure; medical personnel were helpless when it came to fighting the disease, and so the flu went on to infect millions and kill at a rate 25 times higher than the standard.
Selgelid, M. (2007). A Tale of Two Studies:Ethics, Bioterrorism, and the Censorship of Science. Project Muse, 3, 35-43. Retrieved February 13, 2011, from http://journals.ohiolink.edu/ejc/article.cgi?issn=1552146x&issue=v37i0003&article=35_atotsebatcos
Kamradt-Scott, Adam. "The Politics Of Medicine And The Global Governance Of Pandemic Influenza." International Journal Of Health Services: Planning, Administration, Evaluation 43.1 (2013): 105-121. MEDLINE with Full Text. Web. 15 Nov. 2013.
At no time was a search for the cure for influenza more frantic than after the devastating effects of the pandemic of 1918. The pandemic killed somewhere between twenty and a hundred million people, making it twenty five times more deadly than the ordinary cough and sneeze flu. The symptoms of this flu were like something straight out of a horror movie: the victim’s facial complexion changed to a dark, brownish purple, the feet turned black, and they began to cough up blood. Eventually, death was caused, literally by drowning, when the victim’s lungs filled with their own blood. The first scientist to claim to solve the enigma of influenza was Dr. Friedrich Johann Pfeiffer. He isolated a bacterium he named Hemophilus influenzae from the respiratory tract of those who had the flu in the pandemic of 1890. He was believed to be correct in his discovery until the pandemic of 1918, when scientists searched the respiratory tracts of influenza victims and only sometimes found his bacterium. Robert E. Shope and his mentor Paul Lewis were the next to attempt to crack the code of influenza. They chose to study the disease in pigs, a controversial choice because many people believed that the swine influenza pigs were contracting was not the same as the human flu. The first experiment they ran was ba...
Hvistendahl, M, Cohen, J et. al. 2013. ‘New Flu Virus in China Worries and Confuses’ Science 340: 129-130
Recent concerns regarding the risks of Avian flu and other exotic diseases prompted some local poultry farmers to adopt strict biosecurity protocols in order to keep their birds safe. ...
Recent research shows that, there are three major means by which infections can be transmitted and they include direct transmission, indirect transmission and airborne transmission (Hinman,Wasserheit and Kamb,1995). Direct transmission occurs when the physical contact between an infected person and s susceptible person takes place (division of public health, 2011). An example is a health care worker who attends to an Ebola patient, without gloves, gown and mask plus forget to wash his or her hand with soap and hot water and or a person having flu without the use of mask or washes his hand after sneezing easily passes the infection to the other through hand shake or surface touch, living the bacteria there for another vulnerable person to also touch if the surface is not disinfected with bleach. Studies makes it clear that, the spreads takes effect when disease-causing microorganisms pass from the infected person to the healthy person through direct physical contact such as touching of blood, body fluids, contact with oral secretion, bites kissing, contact with body lesions and even sexual contact. However, measles and chicken pox are said to be conditions spread by direct
The Flu was first founded in Seattle September, 1918. The avian flu can also be known as the “Bird Flu”. The bird flu is being passed around by migratory birds. It can be transmitted from birds to mammals and in some limited circumstances to humans. The flu will also be known as the H5N1 virus. The H5N1 virus has raised concerns about a potential human pandemic because its virulent (deadly; extremely dangerous) and it can evolve like other influenza viruses. As many other viruses and illnesses the flu can be a lot more deadlier. When you get the flu the lungs are severely harmed from infected cells called macrophages and T-cells. The virus can spread way beyond the lungs but generally do not. Many people catch the flu and think they have the common cold because of some of the same symptoms. But actually the flu can be more dangerous if you don’t treat it immediately.
The swine influenza or swine flu is a respiratory disease in pigs that is caused by the type A influenza viruses. These viruses are referred to as swine flu viruses but scientifically the main virus is called the swine triple reassortant (tr) H1N1 influenza virus. When the viruses infect humans they are called variant viruses. This infection has been caused in humans mainly by the H1N1v virus in the United States. The H1N1 virus originates in animals due to improper conditions and the food they ingest. The virus stays in latency form, thus harmless to the respective animal. The longer the animals survive the more likely the virus is to develop and strengthen making it immune to vaccines. The virus reproduced through the lytic cycle. The virus injects its own nucleic acids into a host cell and then they form a circle in the center of the cell. Rather than copying its own nucleic acids, the cell will copy the viral acids. The copies of viral acids then organize themselves as viruses inside of the cell. The membrane will eventually split leaving the viruses free to infect other cells.