History of Cloning and the Future Prospect of Cloning Humans

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History of Cloning and the Future Prospect of Cloning Humans

In the first article, the author describes cloning as the process of creating a cell, tissue line or even a complete organism from a single cell. He says that the concept of cloning was introduced in 1903 and plants were the first living organisms to be cloned. He gives examples such as trees sending up runners, worms dividing into smaller worms and says that all these are clones. He then explains the various threads and experiments used over the years and how they have contributed to the field of cloning.

The author states that the first research thread leading to experimental cloning involved laboratory stimulation of development through artificial fertilization. This was proven when artificial parthenogenesis of sea urchin eggs showed that fertilization was not necessary to make larval urchins. Transplantation was the second experimental manipulation of development. Nuclear transplantation was used to produce a clone from embryonic or adult cells. The third line of development was cell line and gene cloning. In this process, the scientists recombine the genetic material. Using nuclear transplantation, the first frog was cloned. After nuclear transplantation came recombinant DNA. This revolutionized the field of genetics presenting new techniques for cloning. Recombinant DNA showed that pieces of DNA could be transplanted from animals into bacteria. And after all this came the major breakthrough in the field of genetics and cloning. That was the cloning of the first sheep, Dolly.

Dolly was a result of reproductive technology. It is a fact that living wombs are required as incubators and they are available because of advances in reproductive technologies and agriculture. Implantation techniques were not new in Dolly, but this step is essential for the process to work. Ian Wilmut and his team used these various established research threads to produce Dolly. There was one detail new in Dolly in a technical fact. That the nucleus came from an adult somatic rather than embryonic cell was not sufficiently radical scientifically that it should have evoked such strong reactions.

The production of Dolly has raised mixed reactions all over the world.

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